ENSG00000185728

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000517371 ENSG00000185728 No_inf pgKDN_inf YTHDF3 protein_coding protein_coding 36.39777 33.77253 41.31401 0.9297706 1.483451 0.2907028 5.444900 10.287509 5.248899 0.7189116 2.045550 -0.9694626 0.1507500 0.304225 0.123875 -0.18035 0.419624085 0.001751017   FALSE
ENST00000539294 ENSG00000185728 No_inf pgKDN_inf YTHDF3 protein_coding protein_coding 36.39777 33.77253 41.31401 0.9297706 1.483451 0.2907028 18.072697 5.307425 27.212772 3.0804490 2.497114 2.3560143 0.4861833 0.157875 0.664175 0.50630 0.276681377 0.001751017 FALSE TRUE
MSTRG.27733.1 ENSG00000185728 No_inf pgKDN_inf YTHDF3 protein_coding   36.39777 33.77253 41.31401 0.9297706 1.483451 0.2907028 3.762556 1.829965 3.818101 0.7843713 0.558950 1.0569504 0.1042417 0.053750 0.092750 0.03900 0.741233033 0.001751017 FALSE TRUE
MSTRG.27733.17 ENSG00000185728 No_inf pgKDN_inf YTHDF3 protein_coding   36.39777 33.77253 41.31401 0.9297706 1.483451 0.2907028 5.756382 14.033912 1.214043 3.1477648 1.214043 -3.5202183 0.1664667 0.415650 0.026550 -0.38910 0.001751017 0.001751017 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000185728 E001 0.6066988 0.0147800687 8.491857e-01 9.464293e-01 8 63168522 63168552 31 + 0.216 0.193 -0.201
ENSG00000185728 E002 0.6066988 0.0147800687 8.491857e-01 9.464293e-01 8 63168553 63168561 9 + 0.216 0.193 -0.201
ENSG00000185728 E003 1.4609998 0.0088158788 8.588598e-01 9.508461e-01 8 63168562 63168620 59 + 0.398 0.380 -0.102
ENSG00000185728 E004 1.8115686 0.0159559924 4.021041e-01 6.852375e-01 8 63168621 63168651 31 + 0.497 0.380 -0.616
ENSG00000185728 E005 2.4299379 0.0438305777 7.117767e-01 8.834798e-01 8 63168652 63168653 2 + 0.553 0.510 -0.201
ENSG00000185728 E006 2.6754300 0.0145146439 7.565310e-01 9.041647e-01 8 63168654 63168654 1 + 0.578 0.546 -0.146
ENSG00000185728 E007 3.7658712 0.0053664018 5.385829e-01 7.871968e-01 8 63168655 63168660 6 + 0.705 0.639 -0.279
ENSG00000185728 E008 5.2351131 0.0175220903 7.550468e-01 9.035894e-01 8 63168661 63168686 26 + 0.803 0.781 -0.090
ENSG00000185728 E009 11.9645069 0.0168282085 3.717199e-02 1.856297e-01 8 63168687 63168814 128 + 1.186 0.998 -0.682
ENSG00000185728 E010 14.4790259 0.0010238262 7.471271e-04 1.197227e-02 8 63168815 63168901 87 + 1.284 1.033 -0.896
ENSG00000185728 E011 0.2362687 0.0156678459 3.323954e-01   8 63168961 63169002 42 + 0.155 0.000 -13.126
ENSG00000185728 E012 0.1186381 0.0118035673 6.770831e-01   8 63169003 63169008 6 + 0.084 0.000 -12.191
ENSG00000185728 E013 0.1186381 0.0118035673 6.770831e-01   8 63169009 63169019 11 + 0.084 0.000 -12.191
ENSG00000185728 E014 0.1186381 0.0118035673 6.770831e-01   8 63169020 63169021 2 + 0.084 0.000 -12.191
ENSG00000185728 E015 0.6191283 0.3839469049 6.962429e-01 8.760405e-01 8 63169022 63169105 84 + 0.155 0.265 0.968
ENSG00000185728 E016 0.5004902 0.5358109429 4.743706e-01 7.411130e-01 8 63169106 63169111 6 + 0.084 0.265 1.969
ENSG00000185728 E017 9.2740405 0.0014944941 2.306636e-03 2.837731e-02 8 63169387 63169388 2 + 1.114 0.837 -1.031
ENSG00000185728 E018 11.4066265 0.0022350582 2.556276e-05 7.600342e-04 8 63169389 63169411 23 + 1.221 0.854 -1.347
ENSG00000185728 E019 0.1186381 0.0118035673 6.770831e-01   8 63169412 63169491 80 + 0.084 0.000 -12.191
ENSG00000185728 E020 0.2346346 0.0156148216 3.323413e-01   8 63170752 63170810 59 + 0.155 0.000 -13.126
ENSG00000185728 E021 1.2227732 0.0107968002 7.182223e-01 8.865872e-01 8 63172653 63172798 146 + 0.316 0.380 0.384
ENSG00000185728 E022 0.0000000       8 63173651 63173681 31 +      
ENSG00000185728 E023 8.7756501 0.0022435985 6.107816e-04 1.019557e-02 8 63175331 63175336 6 + 1.107 0.781 -1.228
ENSG00000185728 E024 18.3425688 0.0008152500 2.259389e-04 4.624588e-03 8 63175337 63175416 80 + 1.379 1.133 -0.866
ENSG00000185728 E025 1.4757533 0.0527991346 3.638868e-01 6.526553e-01 8 63175417 63175700 284 + 0.316 0.471 0.869
ENSG00000185728 E026 197.0820716 0.0001015051 1.995487e-03 2.552766e-02 8 63186147 63187529 1383 + 2.315 2.269 -0.153
ENSG00000185728 E027 49.6012140 0.0019880955 8.395680e-01 9.424368e-01 8 63187530 63187745 216 + 1.700 1.706 0.020
ENSG00000185728 E028 0.2542726 0.2169692330 2.156742e-01   8 63188735 63189042 308 + 0.000 0.193 12.098
ENSG00000185728 E029 604.4753620 0.0009370323 7.955293e-11 8.110789e-09 8 63209683 63212786 3104 + 2.746 2.818 0.241

Help

Please Click HERE to learn more details about the results from DEXseq.