ENSG00000185917

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000332131 ENSG00000185917 No_inf pgKDN_inf SETD4 protein_coding protein_coding 9.548573 11.40174 8.561794 1.359727 1.4486 -0.4128496 0.3913036 0.0000000 1.1739109 0.0000000 0.6897889 6.8874167 0.04626667 0.000000 0.138800 0.138800 0.41095753 0.04274353 FALSE TRUE
ENST00000399201 ENSG00000185917 No_inf pgKDN_inf SETD4 protein_coding protein_coding 9.548573 11.40174 8.561794 1.359727 1.4486 -0.4128496 0.3127411 0.9382232 0.0000000 0.9382232 0.0000000 -6.5671548 0.02161667 0.064850 0.000000 -0.064850 0.87076307 0.04274353 FALSE TRUE
ENST00000399205 ENSG00000185917 No_inf pgKDN_inf SETD4 protein_coding protein_coding 9.548573 11.40174 8.561794 1.359727 1.4486 -0.4128496 0.3375266 1.0125797 0.0000000 0.6038133 0.0000000 -6.6760695 0.02920000 0.087600 0.000000 -0.087600 0.55466747 0.04274353 FALSE TRUE
ENST00000399207 ENSG00000185917 No_inf pgKDN_inf SETD4 protein_coding protein_coding 9.548573 11.40174 8.561794 1.359727 1.4486 -0.4128496 0.6031848 0.0000000 0.8961453 0.0000000 0.8961453 6.5016706 0.06224167 0.000000 0.078925 0.078925 0.81953317 0.04274353 FALSE TRUE
ENST00000399208 ENSG00000185917 No_inf pgKDN_inf SETD4 protein_coding protein_coding 9.548573 11.40174 8.561794 1.359727 1.4486 -0.4128496 0.8473330 0.0000000 1.5780299 0.0000000 0.6379198 7.3110942 0.09930833 0.000000 0.206225 0.206225 0.04274353 0.04274353 FALSE TRUE
ENST00000399212 ENSG00000185917 No_inf pgKDN_inf SETD4 protein_coding protein_coding 9.548573 11.40174 8.561794 1.359727 1.4486 -0.4128496 0.1948577 0.5845731 0.0000000 0.5845731 0.0000000 -5.8937822 0.01726667 0.051800 0.000000 -0.051800 0.88488539 0.04274353 FALSE TRUE
ENST00000446166 ENSG00000185917 No_inf pgKDN_inf SETD4 protein_coding protein_coding 9.548573 11.40174 8.561794 1.359727 1.4486 -0.4128496 0.4834567 0.0000000 0.7172142 0.0000000 0.7172142 6.1843085 0.04664167 0.000000 0.063175 0.063175 0.81715726 0.04274353 FALSE FALSE
ENST00000469482 ENSG00000185917 No_inf pgKDN_inf SETD4 protein_coding protein_coding_CDS_not_defined 9.548573 11.40174 8.561794 1.359727 1.4486 -0.4128496 0.9111290 1.7664988 0.9668883 0.6282501 0.5583609 -0.8627711 0.07570000 0.139350 0.087750 -0.051600 0.84787797 0.04274353 FALSE TRUE
ENST00000481477 ENSG00000185917 No_inf pgKDN_inf SETD4 protein_coding protein_coding_CDS_not_defined 9.548573 11.40174 8.561794 1.359727 1.4486 -0.4128496 0.4670968 0.4164116 0.0000000 0.2443565 0.0000000 -5.4141749 0.05674167 0.032175 0.000000 -0.032175 0.58314681 0.04274353 TRUE FALSE
ENST00000487297 ENSG00000185917 No_inf pgKDN_inf SETD4 protein_coding retained_intron 9.548573 11.40174 8.561794 1.359727 1.4486 -0.4128496 0.5217468 0.8211139 0.2504201 0.1324784 0.1488553 -1.6742055 0.05944167 0.079900 0.037875 -0.042025 0.70598194 0.04274353 FALSE TRUE
MSTRG.18767.7 ENSG00000185917 No_inf pgKDN_inf SETD4 protein_coding   9.548573 11.40174 8.561794 1.359727 1.4486 -0.4128496 0.6608073 1.1723818 0.0000000 0.6912314 0.0000000 -6.8855522 0.07580000 0.119625 0.000000 -0.119625 0.59836033 0.04274353 TRUE TRUE
MSTRG.18767.8 ENSG00000185917 No_inf pgKDN_inf SETD4 protein_coding   9.548573 11.40174 8.561794 1.359727 1.4486 -0.4128496 1.2957389 1.3446286 1.0535560 0.5814794 0.3693393 -0.3490014 0.15090000 0.140150 0.147275 0.007125 0.97182665 0.04274353 TRUE TRUE
MSTRG.18767.9 ENSG00000185917 No_inf pgKDN_inf SETD4 protein_coding   9.548573 11.40174 8.561794 1.359727 1.4486 -0.4128496 1.4024813 2.0501916 0.7453760 0.4563551 0.3474933 -1.4475117 0.14434167 0.182450 0.097550 -0.084900 0.66291509 0.04274353   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000185917 E001 0.0000000       21 36034541 36034541 1 -      
ENSG00000185917 E002 0.0000000       21 36034542 36034542 1 -      
ENSG00000185917 E003 0.1268540 0.012602704 1.000000000   21 36034543 36034543 1 - 0.000 0.074 8.500
ENSG00000185917 E004 0.6066337 0.014701209 0.281665267 0.5750069 21 36034544 36034551 8 - 0.293 0.138 -1.364
ENSG00000185917 E005 10.9702117 0.001992253 0.023241016 0.1392447 21 36034552 36034932 381 - 0.906 1.125 0.806
ENSG00000185917 E006 26.8935069 0.021221065 0.020845501 0.1301505 21 36034933 36035960 1028 - 1.292 1.485 0.667
ENSG00000185917 E007 1.8780326 0.007195655 0.175855752 0.4499932 21 36035961 36036084 124 - 0.293 0.511 1.221
ENSG00000185917 E008 6.3912077 0.002370604 0.225025743 0.5126526 21 36036085 36036251 167 - 0.923 0.807 -0.444
ENSG00000185917 E009 3.5880449 0.055857608 0.883105920 0.9606058 21 36036518 36036827 310 - 0.624 0.658 0.148
ENSG00000185917 E010 7.6483164 0.020839983 0.546232559 0.7920556 21 36038150 36038273 124 - 0.955 0.898 -0.213
ENSG00000185917 E011 4.8571695 0.049798455 0.378001265 0.6651498 21 36040575 36040655 81 - 0.656 0.795 0.569
ENSG00000185917 E012 3.9642530 0.028631937 0.874738490 0.9571545 21 36041807 36041888 82 - 0.656 0.692 0.154
ENSG00000185917 E013 4.7391321 0.110479054 0.207914668 0.4916120 21 36041889 36043373 1485 - 0.589 0.807 0.910
ENSG00000185917 E014 4.7200351 0.003549882 0.556257167 0.7986248 21 36043401 36043651 251 - 0.685 0.768 0.337
ENSG00000185917 E015 0.3712740 0.017172750 1.000000000   21 36043686 36043697 12 - 0.121 0.138 0.221
ENSG00000185917 E016 1.0902228 0.010841138 0.065100785 0.2570284 21 36043698 36043781 84 - 0.466 0.193 -1.779
ENSG00000185917 E017 8.3463656 0.001771051 0.060474245 0.2467931 21 36043782 36043956 175 - 1.051 0.888 -0.609
ENSG00000185917 E018 5.4642178 0.003156631 0.547652745 0.7930914 21 36045582 36045613 32 - 0.739 0.820 0.321
ENSG00000185917 E019 5.0782410 0.051848521 0.975535597 0.9956858 21 36045614 36045630 17 - 0.764 0.768 0.014
ENSG00000185917 E020 9.5005424 0.006994896 0.466432709 0.7351212 21 36045631 36045782 152 - 1.039 0.982 -0.209
ENSG00000185917 E021 5.3773069 0.053959321 0.088072531 0.3078486 21 36045783 36045863 81 - 0.923 0.692 -0.909
ENSG00000185917 E022 5.1029560 0.003320702 0.002078999 0.0263213 21 36045864 36045964 101 - 0.955 0.621 -1.335
ENSG00000185917 E023 3.5652004 0.006013150 0.336535584 0.6284654 21 36045965 36046011 47 - 0.713 0.601 -0.479
ENSG00000185917 E024 2.9406911 0.041602347 0.207546492 0.4911153 21 36048308 36048321 14 - 0.686 0.511 -0.779
ENSG00000185917 E025 4.8280068 0.055005358 0.985654540 0.9990658 21 36048322 36048396 75 - 0.740 0.754 0.057
ENSG00000185917 E026 0.0000000       21 36052917 36053582 666 -      
ENSG00000185917 E027 3.2267186 0.028346130 0.602762536 0.8266431 21 36053583 36053588 6 - 0.552 0.640 0.391
ENSG00000185917 E028 3.9621606 0.083199415 0.909036163 0.9711391 21 36053589 36053620 32 - 0.656 0.692 0.154
ENSG00000185917 E029 5.0608839 0.003179433 0.699897252 0.8776315 21 36057109 36057204 96 - 0.787 0.754 -0.135
ENSG00000185917 E030 0.0000000       21 36057205 36057301 97 -      
ENSG00000185917 E031 1.7604332 0.031725183 0.077134786 0.2840882 21 36057384 36057477 94 - 0.215 0.511 1.806
ENSG00000185917 E032 4.6747487 0.003423602 0.274596688 0.5681520 21 36058816 36058924 109 - 0.810 0.692 -0.474
ENSG00000185917 E033 2.1113436 0.025258385 0.578862797 0.8118088 21 36058925 36058973 49 - 0.415 0.511 0.484
ENSG00000185917 E034 0.3806233 0.015969364 0.271566101   21 36058974 36059821 848 - 0.000 0.193 12.311
ENSG00000185917 E035 0.0000000       21 36059822 36060106 285 -      
ENSG00000185917 E036 0.0000000       21 36060107 36060261 155 -      
ENSG00000185917 E037 0.1265070 0.012420469 1.000000000   21 36060282 36060346 65 - 0.000 0.074 10.912
ENSG00000185917 E038 2.0701793 0.006876276 0.059206190 0.2442406 21 36060347 36060527 181 - 0.624 0.363 -1.293
ENSG00000185917 E039 0.0000000       21 36079305 36079389 85 -      

Help

Please Click HERE to learn more details about the results from DEXseq.