ENSG00000186001

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000414675 ENSG00000186001 No_inf pgKDN_inf LRCH3 protein_coding protein_coding 12.50953 11.83738 10.08062 0.7409876 0.5274587 -0.2315531 0.4883001 0.000000 1.4649004 0.0000000 0.2965059 7.2044737 0.05000000 0.000000 0.150000 0.150000 0.001045368 0.001045368 FALSE TRUE
ENST00000425562 ENSG00000186001 No_inf pgKDN_inf LRCH3 protein_coding protein_coding 12.50953 11.83738 10.08062 0.7409876 0.5274587 -0.2315531 2.8387911 1.828476 4.2442283 1.0731958 1.4408567 1.2103872 0.24101667 0.145575 0.434600 0.289025 0.610712077 0.001045368 FALSE TRUE
ENST00000433298 ENSG00000186001 No_inf pgKDN_inf LRCH3 protein_coding protein_coding 12.50953 11.83738 10.08062 0.7409876 0.5274587 -0.2315531 1.0886695 1.373478 1.1928518 0.7945004 0.7311464 -0.2018405 0.10175833 0.128025 0.117375 -0.010650 1.000000000 0.001045368 FALSE TRUE
ENST00000476664 ENSG00000186001 No_inf pgKDN_inf LRCH3 protein_coding retained_intron 12.50953 11.83738 10.08062 0.7409876 0.5274587 -0.2315531 2.2772587 2.017466 0.4337647 1.1801101 0.4337647 -2.1918107 0.14942500 0.155675 0.039050 -0.116625 0.817908529 0.001045368   FALSE
ENST00000493726 ENSG00000186001 No_inf pgKDN_inf LRCH3 protein_coding protein_coding_CDS_not_defined 12.50953 11.83738 10.08062 0.7409876 0.5274587 -0.2315531 1.1133779 1.778285 0.4259985 0.2377126 0.2462994 -2.0361818 0.08468333 0.149350 0.039175 -0.110175 0.309552564 0.001045368   FALSE
MSTRG.21381.9 ENSG00000186001 No_inf pgKDN_inf LRCH3 protein_coding   12.50953 11.83738 10.08062 0.7409876 0.5274587 -0.2315531 2.3094413 2.704714 1.3328816 1.2080316 1.3328816 -1.0154679 0.19334167 0.244450 0.125400 -0.119050 0.513803385 0.001045368 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000186001 E001 0.0000000       3 197791226 197791234 9 +      
ENSG00000186001 E002 0.0000000       3 197791235 197791242 8 +      
ENSG00000186001 E003 0.0000000       3 197791243 197791253 11 +      
ENSG00000186001 E004 0.2454921 0.0165256753 0.9005030864   3 197791254 197791263 10 + 0.088 0.103 0.243
ENSG00000186001 E005 0.6079882 0.2349494051 0.8078364445 0.929104442 3 197791264 197791273 10 + 0.224 0.185 -0.342
ENSG00000186001 E006 1.1078789 0.1696502948 0.6035928664 0.827045822 3 197791274 197791281 8 + 0.279 0.368 0.565
ENSG00000186001 E007 5.1366524 0.0028557220 0.8347900409 0.940519633 3 197791282 197791540 259 + 0.775 0.801 0.106
ENSG00000186001 E008 5.2998730 0.0029689829 0.0111203489 0.086197887 3 197814908 197815052 145 + 0.914 0.623 -1.172
ENSG00000186001 E009 6.7248029 0.0021882302 0.0004118065 0.007485801 3 197817176 197817302 127 + 1.028 0.649 -1.483
ENSG00000186001 E010 2.6310569 0.0066545109 0.0066226471 0.060653057 3 197820325 197820332 8 + 0.703 0.315 -1.927
ENSG00000186001 E011 5.4301584 0.0029434823 0.0194061781 0.124527401 3 197820333 197820430 98 + 0.914 0.649 -1.057
ENSG00000186001 E012 0.0000000       3 197822831 197823465 635 +      
ENSG00000186001 E013 5.5851089 0.0026394823 0.2165081706 0.502653854 3 197826878 197827014 137 + 0.876 0.742 -0.527
ENSG00000186001 E014 2.6924858 0.0052640979 0.7110317764 0.883205616 3 197829564 197829673 110 + 0.541 0.594 0.243
ENSG00000186001 E015 0.0000000       3 197830770 197830863 94 +      
ENSG00000186001 E016 2.3334517 0.0058783742 0.5664117053 0.804695352 3 197832197 197832317 121 + 0.481 0.564 0.395
ENSG00000186001 E017 3.8770512 0.0040050683 0.1853208016 0.463057314 3 197835674 197835738 65 + 0.758 0.594 -0.690
ENSG00000186001 E018 4.4756267 0.0052906983 0.0977003109 0.325812686 3 197835739 197835796 58 + 0.821 0.623 -0.816
ENSG00000186001 E019 3.7480900 0.0039238683 0.1217137809 0.369259366 3 197835797 197835822 26 + 0.758 0.564 -0.827
ENSG00000186001 E020 5.2270884 0.0049762430 0.3988546480 0.682693022 3 197839321 197839397 77 + 0.836 0.742 -0.370
ENSG00000186001 E021 4.0200575 0.0051153498 0.6835904721 0.869034025 3 197847409 197847460 52 + 0.722 0.675 -0.197
ENSG00000186001 E022 0.0000000       3 197847845 197847871 27 +      
ENSG00000186001 E023 5.2658029 0.0283715964 0.5645721308 0.803759722 3 197847872 197847958 87 + 0.758 0.836 0.310
ENSG00000186001 E024 4.4164321 0.0085338310 0.4277996844 0.706332958 3 197847959 197848000 42 + 0.683 0.782 0.404
ENSG00000186001 E025 4.0902877 0.0236070913 0.0271131600 0.153072459 3 197848001 197848021 21 + 0.541 0.836 1.243
ENSG00000186001 E026 0.9972659 0.0274332309 0.1030715149 0.335533248 3 197848022 197848499 478 + 0.161 0.415 1.828
ENSG00000186001 E027 0.1271363 0.0123920809 0.4582455730   3 197852328 197852560 233 + 0.000 0.103 12.004
ENSG00000186001 E028 5.1817393 0.0047053170 0.0831607490 0.297150645 3 197852561 197852620 60 + 0.683 0.884 0.800
ENSG00000186001 E029 0.0000000       3 197854390 197854391 2 +      
ENSG00000186001 E030 3.0959596 0.0049394621 0.0731089711 0.274720055 3 197854392 197854445 54 + 0.481 0.721 1.073
ENSG00000186001 E031 0.0000000       3 197858818 197858820 3 +      
ENSG00000186001 E032 0.0000000       3 197858821 197858821 1 +      
ENSG00000186001 E033 0.0000000       3 197858822 197858833 12 +      
ENSG00000186001 E034 2.1862093 0.0073713443 0.5471016573 0.792621105 3 197858834 197858905 72 + 0.541 0.457 -0.409
ENSG00000186001 E035 0.5070043 0.0157145039 0.0306894041 0.164783584 3 197858906 197859439 534 + 0.000 0.315 13.795
ENSG00000186001 E036 3.5480757 0.0232165163 0.8244372290 0.936267108 3 197865423 197865471 49 + 0.641 0.675 0.144
ENSG00000186001 E037 6.1327171 0.0022197526 0.3973516659 0.681488369 3 197866112 197866219 108 + 0.806 0.899 0.359
ENSG00000186001 E038 9.3326822 0.0016196464 0.1649433614 0.434424697 3 197870160 197870278 119 + 0.948 1.076 0.471
ENSG00000186001 E039 9.6327586 0.0014748202 0.7594204129 0.905588424 3 197871325 197871422 98 + 1.037 1.014 -0.087
ENSG00000186001 E040 5.3512553 0.0039844923 0.4997095597 0.759920357 3 197871423 197871462 40 + 0.836 0.763 -0.287
ENSG00000186001 E041 0.2352613 0.2353995072 0.3562308788   3 197871463 197871585 123 + 0.161 0.000 -12.990
ENSG00000186001 E042 0.1176306 0.0117964168 0.6300228533   3 197875694 197875697 4 + 0.088 0.000 -12.507
ENSG00000186001 E043 6.9195855 0.0346142778 0.3536883566 0.643357727 3 197875698 197875775 78 + 0.948 0.836 -0.427
ENSG00000186001 E044 0.6346136 0.0144000510 0.0127459505 0.094015330 3 197875776 197876340 565 + 0.000 0.368 14.071
ENSG00000186001 E045 0.8880360 0.0124054022 0.0023636879 0.028913452 3 197880512 197880757 246 + 0.000 0.457 14.476
ENSG00000186001 E046 4.8019994 0.0029644599 0.1948413030 0.474877800 3 197880758 197883376 2619 + 0.683 0.836 0.615
ENSG00000186001 E047 32.3586939 0.0025503798 0.9918635375 1.000000000 3 197883541 197884249 709 + 1.521 1.525 0.014
ENSG00000186001 E048 49.2623578 0.0112748840 0.5165234376 0.772272200 3 197884250 197885517 1268 + 1.715 1.685 -0.101
ENSG00000186001 E049 48.8289226 0.0005631596 0.0093708392 0.077055472 3 197885518 197888436 2919 + 1.643 1.749 0.359

Help

Please Click HERE to learn more details about the results from DEXseq.