ENSG00000186111

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000335312 ENSG00000186111 No_inf pgKDN_inf PIP5K1C protein_coding protein_coding 43.05221 32.78403 36.99348 0.9183495 1.964211 0.1742279 5.7740235 3.722546 7.438487 0.7499067 1.0860719 0.9967874 0.15566667 0.115250 0.205075 0.089825 0.5596505275 0.0002253028 FALSE  
ENST00000539785 ENSG00000186111 No_inf pgKDN_inf PIP5K1C protein_coding protein_coding 43.05221 32.78403 36.99348 0.9183495 1.964211 0.1742279 1.2702266 0.000000 2.259133 0.0000000 2.2591334 7.8259976 0.02959167 0.000000 0.052850 0.052850 0.8464350541 0.0002253028 FALSE  
ENST00000592530 ENSG00000186111 No_inf pgKDN_inf PIP5K1C protein_coding protein_coding_CDS_not_defined 43.05221 32.78403 36.99348 0.9183495 1.964211 0.1742279 0.9432148 2.312046 0.000000 0.5817053 0.0000000 -7.8592530 0.02827500 0.071375 0.000000 -0.071375 0.0002253028 0.0002253028 FALSE  
ENST00000636612 ENSG00000186111 No_inf pgKDN_inf PIP5K1C protein_coding protein_coding_CDS_not_defined 43.05221 32.78403 36.99348 0.9183495 1.964211 0.1742279 7.0749195 0.000000 0.000000 0.0000000 0.0000000 0.0000000 0.05900000 0.000000 0.000000 0.000000   0.0002253028    
MSTRG.14300.1 ENSG00000186111 No_inf pgKDN_inf PIP5K1C protein_coding   43.05221 32.78403 36.99348 0.9183495 1.964211 0.1742279 2.2645651 3.321014 1.592369 0.9507713 0.6647992 -1.0557550 0.05870833 0.100875 0.042825 -0.058050 0.6092024692 0.0002253028 FALSE  
MSTRG.14300.6 ENSG00000186111 No_inf pgKDN_inf PIP5K1C protein_coding   43.05221 32.78403 36.99348 0.9183495 1.964211 0.1742279 5.2351710 3.751086 6.325826 2.1670796 1.5368340 0.7523834 0.12790000 0.116675 0.175600 0.058925 0.6976414627 0.0002253028 FALSE  
MSTRG.14300.8 ENSG00000186111 No_inf pgKDN_inf PIP5K1C protein_coding   43.05221 32.78403 36.99348 0.9183495 1.964211 0.1742279 15.3137466 14.062507 16.484947 1.4376304 2.0907217 0.2291447 0.39966667 0.426875 0.441725 0.014850 0.9779255563 0.0002253028 FALSE  
MSTRG.14300.9 ENSG00000186111 No_inf pgKDN_inf PIP5K1C protein_coding   43.05221 32.78403 36.99348 0.9183495 1.964211 0.1742279 3.5348778 3.234298 1.857199 2.0441130 1.8571988 -0.7970310 0.09748333 0.095875 0.052825 -0.043050 0.8087513828 0.0002253028 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000186111 E001 0.1272623 0.0122945111 4.970989e-01   19 3630182 3630182 1 - 0.000 0.098 9.929
ENSG00000186111 E002 0.2448930 0.0162525178 9.510387e-01   19 3630183 3630192 10 - 0.092 0.098 0.113
ENSG00000186111 E003 0.3717469 0.0165268631 5.355097e-01   19 3630193 3630194 2 - 0.092 0.179 1.113
ENSG00000186111 E004 0.7353431 0.0425690515 9.254067e-01 9.775645e-01 19 3630195 3630195 1 - 0.232 0.246 0.113
ENSG00000186111 E005 1.0886809 0.0124220330 3.786549e-01 6.656064e-01 19 3630196 3630221 26 - 0.382 0.246 -0.887
ENSG00000186111 E006 443.5640630 0.0001404016 3.987924e-02 1.935345e-01 19 3630222 3632875 2654 - 2.638 2.658 0.065
ENSG00000186111 E007 53.5922048 0.0009386206 8.712728e-01 9.557633e-01 19 3632876 3633155 280 - 1.734 1.740 0.021
ENSG00000186111 E008 14.0573985 0.0009766836 8.213959e-01 9.351762e-01 19 3633156 3633169 14 - 1.186 1.169 -0.063
ENSG00000186111 E009 2.9617966 0.1014387454 4.056322e-01 6.883337e-01 19 3633170 3633436 267 - 0.526 0.659 0.597
ENSG00000186111 E010 9.3126197 0.0041659621 5.745353e-01 8.095035e-01 19 3633437 3633520 84 - 0.987 1.039 0.189
ENSG00000186111 E011 5.7705768 0.0024599619 1.407319e-06 6.247104e-05 19 3636601 3637535 935 - 0.460 1.028 2.361
ENSG00000186111 E012 1.1252538 0.0121187036 7.067339e-02 2.692524e-01 19 3637536 3637613 78 - 0.168 0.444 1.921
ENSG00000186111 E013 3.2380456 0.0105762739 1.186360e-02 8.986711e-02 19 3637614 3638006 393 - 0.423 0.766 1.554
ENSG00000186111 E014 29.5601032 0.0005792093 6.809892e-01 8.681671e-01 19 3638884 3639016 133 - 1.496 1.474 -0.078
ENSG00000186111 E015 0.4901058 0.0158045467 9.375493e-01   19 3639017 3639036 20 - 0.168 0.179 0.113
ENSG00000186111 E016 12.9816628 0.0012524855 2.797149e-02 1.562218e-01 19 3641705 3641809 105 - 1.224 1.049 -0.631
ENSG00000186111 E017 5.4981039 0.0026752034 8.582132e-01 9.505500e-01 19 3642907 3642939 33 - 0.823 0.802 -0.080
ENSG00000186111 E018 0.5003641 0.0239074832 2.853174e-01 5.790085e-01 19 3642940 3642991 52 - 0.092 0.246 1.698
ENSG00000186111 E019 15.3761597 0.0413370602 5.969036e-01 8.229447e-01 19 3643243 3643381 139 - 1.243 1.183 -0.209
ENSG00000186111 E020 6.0043813 0.0066039279 6.840882e-01 8.692355e-01 19 3644087 3644088 2 - 0.823 0.867 0.172
ENSG00000186111 E021 19.9775585 0.0006903776 4.579169e-01 7.298038e-01 19 3644089 3644251 163 - 1.297 1.345 0.166
ENSG00000186111 E022 11.9527961 0.0101577647 4.630211e-01 7.331076e-01 19 3645974 3646058 85 - 1.144 1.077 -0.242
ENSG00000186111 E023 7.9201058 0.0017358601 4.287549e-01 7.071703e-01 19 3647338 3647386 49 - 0.987 0.910 -0.289
ENSG00000186111 E024 9.4131792 0.0015920913 9.950612e-01 1.000000e+00 19 3648625 3648708 84 - 1.018 1.018 0.001
ENSG00000186111 E025 0.0000000       19 3649355 3649429 75 -      
ENSG00000186111 E026 0.0000000       19 3649891 3650023 133 -      
ENSG00000186111 E027 17.4072255 0.0008324610 1.471534e-01 4.083018e-01 19 3651826 3652031 206 - 1.312 1.211 -0.355
ENSG00000186111 E028 28.3795638 0.0004987667 9.355399e-01 9.815051e-01 19 3653290 3653589 300 - 1.466 1.470 0.014
ENSG00000186111 E029 18.3124286 0.0086287519 5.689760e-01 8.061353e-01 19 3656405 3656557 153 - 1.308 1.263 -0.157
ENSG00000186111 E030 0.1186381 0.0118143323 5.822983e-01   19 3656558 3656592 35 - 0.092 0.000 -12.574
ENSG00000186111 E031 15.7458941 0.0015970320 6.089940e-01 8.298505e-01 19 3660966 3661083 118 - 1.242 1.205 -0.133
ENSG00000186111 E032 0.3706473 0.0165314490 5.354779e-01   19 3661373 3661526 154 - 0.092 0.179 1.113
ENSG00000186111 E033 11.3527371 0.0015998401 7.341576e-01 8.944241e-01 19 3661871 3661929 59 - 1.106 1.077 -0.104
ENSG00000186111 E034 12.6577492 0.0470998119 4.383735e-01 7.145994e-01 19 3661930 3662001 72 - 1.179 1.086 -0.334
ENSG00000186111 E035 6.9011082 0.0364158905 1.041625e-01 3.372293e-01 19 3664822 3664856 35 - 0.987 0.785 -0.774
ENSG00000186111 E036 6.4227669 0.0020975389 7.653574e-02 2.828874e-01 19 3664857 3664914 58 - 0.954 0.766 -0.726
ENSG00000186111 E037 5.3131570 0.0042263579 1.431404e-02 1.017413e-01 19 3667322 3667353 32 - 0.919 0.634 -1.141
ENSG00000186111 E038 0.0000000       19 3667430 3667472 43 -      
ENSG00000186111 E039 0.2533610 0.0160082841 2.161532e-01   19 3668404 3668440 37 - 0.000 0.179 12.844
ENSG00000186111 E040 0.1186381 0.0118143323 5.822983e-01   19 3669673 3669904 232 - 0.092 0.000 -12.574
ENSG00000186111 E041 6.0294566 0.0023651219 1.033005e-02 8.201691e-02 19 3700297 3700468 172 - 0.966 0.683 -1.109

Help

Please Click HERE to learn more details about the results from DEXseq.