ENSG00000186298

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000335007 ENSG00000186298 No_inf pgKDN_inf PPP1CC protein_coding protein_coding 85.61524 85.44699 95.07473 2.18379 7.251395 0.1540153 47.102059 52.726010 48.367700 1.409932 2.478630 -0.1244462 0.55526667 0.617625 0.521300 -0.096325 0.571650812 0.006192202 FALSE TRUE
ENST00000546904 ENSG00000186298 No_inf pgKDN_inf PPP1CC protein_coding retained_intron 85.61524 85.44699 95.07473 2.18379 7.251395 0.1540153 15.471609 17.354377 14.544705 1.462925 1.716673 -0.2546450 0.18186667 0.202875 0.152400 -0.050475 0.626385660 0.006192202   FALSE
ENST00000550261 ENSG00000186298 No_inf pgKDN_inf PPP1CC protein_coding nonsense_mediated_decay 85.61524 85.44699 95.07473 2.18379 7.251395 0.1540153 6.556391 6.344413 7.515242 2.307843 4.360292 0.2439791 0.07393333 0.073700 0.071300 -0.002400 0.913619902 0.006192202 FALSE TRUE
MSTRG.7175.2 ENSG00000186298 No_inf pgKDN_inf PPP1CC protein_coding   85.61524 85.44699 95.07473 2.18379 7.251395 0.1540153 8.862236 1.759278 16.594423 1.759278 1.702433 3.2303346 0.10245833 0.021925 0.176825 0.154900 0.006192202 0.006192202 FALSE TRUE
MSTRG.7175.6 ENSG00000186298 No_inf pgKDN_inf PPP1CC protein_coding   85.61524 85.44699 95.07473 2.18379 7.251395 0.1540153 4.651517 3.161610 5.315522 3.161610 3.313772 0.7477078 0.05178333 0.035725 0.049400 0.013675 0.839167787 0.006192202 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000186298 E001 18.9596037 0.0049665409 0.078315263 0.28649904 12 110719680 110719907 228 - 1.229 1.356 0.444
ENSG00000186298 E002 34.7059896 0.0026251877 0.495427498 0.75658710 12 110719908 110719982 75 - 1.533 1.569 0.123
ENSG00000186298 E003 133.7445523 0.0001270916 0.092486694 0.31582503 12 110719983 110720204 222 - 2.107 2.149 0.139
ENSG00000186298 E004 102.3665014 0.0001760675 0.455692399 0.72810884 12 110720205 110720365 161 - 2.003 2.024 0.070
ENSG00000186298 E005 188.2208601 0.0001068538 0.006991581 0.06299878 12 110720366 110720729 364 - 2.247 2.302 0.185
ENSG00000186298 E006 40.8944900 0.0004990518 0.224570401 0.51207864 12 110720730 110720747 18 - 1.592 1.648 0.190
ENSG00000186298 E007 108.7122444 0.0001697741 0.628479288 0.84047612 12 110720748 110720920 173 - 2.047 2.033 -0.049
ENSG00000186298 E008 116.3058684 0.0001601145 0.635211862 0.84424634 12 110720921 110721104 184 - 2.076 2.062 -0.046
ENSG00000186298 E009 67.1323373 0.0052684773 0.895114190 0.96529080 12 110721105 110721165 61 - 1.838 1.828 -0.031
ENSG00000186298 E010 1.1339079 0.0172759028 0.014942175 0.10477528 12 110721301 110721769 469 - 0.095 0.470 2.990
ENSG00000186298 E011 5.0429036 0.0026830907 0.448467111 0.72247155 12 110721770 110722134 365 - 0.734 0.820 0.344
ENSG00000186298 E012 85.2485781 0.0017069451 0.852246708 0.94779211 12 110722135 110722269 135 - 1.939 1.931 -0.026
ENSG00000186298 E013 10.6289195 0.0014170866 0.019320600 0.12421745 12 110722270 110722471 202 - 0.947 1.151 0.745
ENSG00000186298 E014 45.2015299 0.0004951490 0.994357421 1.00000000 12 110722472 110722528 57 - 1.665 1.664 -0.002
ENSG00000186298 E015 54.5661154 0.0012758069 0.084121104 0.29945137 12 110722529 110722623 95 - 1.781 1.708 -0.249
ENSG00000186298 E016 47.8183015 0.0009331632 0.034219162 0.17650014 12 110722624 110722695 72 - 1.735 1.640 -0.320
ENSG00000186298 E017 63.9191277 0.0002402074 0.011472043 0.08803830 12 110724660 110724764 105 - 1.859 1.764 -0.319
ENSG00000186298 E018 1.2243452 0.0171525103 0.993551313 1.00000000 12 110724765 110726679 1915 - 0.348 0.346 -0.010
ENSG00000186298 E019 0.1187032 0.0118422661 0.535655596   12 110730525 110730528 4 - 0.095 0.000 -8.236
ENSG00000186298 E020 60.1351042 0.0002513539 0.252295027 0.54378456 12 110730529 110730650 122 - 1.809 1.764 -0.150
ENSG00000186298 E021 46.2063057 0.0073674463 0.453040850 0.72589362 12 110730651 110730759 109 - 1.696 1.652 -0.147
ENSG00000186298 E022 24.4904840 0.0110044264 0.088008565 0.30768991 12 110731770 110731815 46 - 1.466 1.342 -0.429
ENSG00000186298 E023 33.4314012 0.0004251409 0.107528098 0.34375211 12 110731816 110731901 86 - 1.578 1.495 -0.284
ENSG00000186298 E024 1.2604123 0.0097584516 0.007549992 0.06650356 12 110731902 110732983 1082 - 0.095 0.505 3.160
ENSG00000186298 E025 0.3719991 0.0166848817 0.586563028   12 110734718 110734986 269 - 0.095 0.173 0.990
ENSG00000186298 E026 25.2423063 0.0005335922 0.807040675 0.92881232 12 110742653 110742939 287 - 1.412 1.425 0.046

Help

Please Click HERE to learn more details about the results from DEXseq.