ENSG00000186350

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000481739 ENSG00000186350 No_inf pgKDN_inf RXRA protein_coding protein_coding 60.51039 38.78478 67.07503 0.1106396 0.5807597 0.7901284 42.555488 21.8140563 53.648100 1.6791322 3.360174 1.297877 0.68370833 0.562525 0.799700 0.237175 0.021574548 0.009906711 FALSE TRUE
MSTRG.29485.10 ENSG00000186350 No_inf pgKDN_inf RXRA protein_coding   60.51039 38.78478 67.07503 0.1106396 0.5807597 0.7901284 8.841650 16.0279532 3.294796 1.5607569 2.587366 -2.278857 0.18613333 0.413175 0.049375 -0.363800 0.009906711 0.009906711 FALSE TRUE
MSTRG.29485.11 ENSG00000186350 No_inf pgKDN_inf RXRA protein_coding   60.51039 38.78478 67.07503 0.1106396 0.5807597 0.7901284 2.870769 0.2027951 4.939328 0.2027951 1.638745 4.539696 0.04148333 0.005225 0.073600 0.068375 0.038561921 0.009906711 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000186350 E001 0.0000000       9 134317098 134317502 405 +      
ENSG00000186350 E002 0.0000000       9 134319438 134319484 47 +      
ENSG00000186350 E003 25.3388322 4.453065e-03 9.523927e-03 7.792225e-02 9 134326455 134326659 205 + 1.476 1.301 -0.606
ENSG00000186350 E004 0.0000000       9 134371971 134372139 169 +      
ENSG00000186350 E005 0.1170040 1.170319e-02 8.714378e-01   9 134373080 134373093 14 + 0.078 0.000 -11.077
ENSG00000186350 E006 0.5916865 1.530966e-02 6.521958e-02 2.571123e-01 9 134373094 134373180 87 + 0.296 0.000 -13.285
ENSG00000186350 E007 1.4316644 2.207758e-01 6.658584e-02 2.599512e-01 9 134374007 134374130 124 + 0.499 0.116 -2.812
ENSG00000186350 E008 0.0000000       9 134379295 134379410 116 +      
ENSG00000186350 E009 0.2352613 2.426319e-01 5.001696e-01   9 134379411 134380163 753 + 0.143 0.000 -10.944
ENSG00000186350 E010 0.4720409 1.585886e-02 1.188058e-01   9 134382530 134382582 53 + 0.251 0.000 -12.960
ENSG00000186350 E011 0.0000000       9 134386122 134386390 269 +      
ENSG00000186350 E012 0.2357071 1.567347e-02 4.404265e-01   9 134391609 134391659 51 + 0.143 0.000 -11.979
ENSG00000186350 E013 0.7177503 1.350422e-02 2.461977e-01 5.368803e-01 9 134401396 134401540 145 + 0.296 0.116 -1.672
ENSG00000186350 E014 49.6061347 2.983307e-04 2.199394e-04 4.520659e-03 9 134401632 134401882 251 + 1.757 1.591 -0.561
ENSG00000186350 E015 11.7761855 5.255013e-03 3.217277e-07 1.671682e-05 9 134401883 134406394 4512 + 0.861 1.308 1.627
ENSG00000186350 E016 2.4812217 5.447777e-02 8.820290e-04 1.363467e-02 9 134407158 134407492 335 + 0.691 0.116 -3.671
ENSG00000186350 E017 34.6081483 7.986749e-04 6.615466e-02 2.590001e-01 9 134408149 134408299 151 + 1.581 1.483 -0.335
ENSG00000186350 E018 46.2696051 1.720552e-03 1.764785e-01 4.506389e-01 9 134408940 134409119 180 + 1.693 1.627 -0.222
ENSG00000186350 E019 73.9033125 2.578820e-04 2.659238e-03 3.150776e-02 9 134417158 134417327 170 + 1.908 1.799 -0.368
ENSG00000186350 E020 63.7154219 2.449375e-04 6.250831e-02 2.511676e-01 9 134421676 134421805 130 + 1.831 1.759 -0.245
ENSG00000186350 E021 49.0437473 1.268840e-03 6.144602e-01 8.325244e-01 9 134429108 134429240 133 + 1.701 1.678 -0.080
ENSG00000186350 E022 44.5765394 3.613048e-04 1.288832e-01 3.808450e-01 9 134431905 134431996 92 + 1.679 1.608 -0.240
ENSG00000186350 E023 54.8836978 2.662186e-04 3.844490e-03 4.132369e-02 9 134434102 134434207 106 + 1.785 1.663 -0.413
ENSG00000186350 E024 327.8011034 1.137763e-04 2.205709e-01 5.075202e-01 9 134436467 134438254 1788 + 2.517 2.497 -0.066
ENSG00000186350 E025 815.1580928 4.568668e-05 2.002312e-13 2.841913e-11 9 134438255 134440585 2331 + 2.881 2.936 0.185

Help

Please Click HERE to learn more details about the results from DEXseq.