ENSG00000186517

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000368013 ENSG00000186517 No_inf pgKDN_inf ARHGAP30 protein_coding protein_coding 118.5689 99.23061 127.8338 0.5048846 1.143482 0.36538 54.694697 34.194203 70.087853 3.363581 4.034974 1.035197 0.45310000 0.345100 0.548800 0.203700 0.02085322 0.01468779 FALSE TRUE
ENST00000368015 ENSG00000186517 No_inf pgKDN_inf ARHGAP30 protein_coding protein_coding 118.5689 99.23061 127.8338 0.5048846 1.143482 0.36538 14.698262 14.057124 15.958750 2.961262 5.483205 0.182924 0.12480000 0.141225 0.124500 -0.016725 0.88556404 0.01468779 FALSE TRUE
MSTRG.2107.13 ENSG00000186517 No_inf pgKDN_inf ARHGAP30 protein_coding   118.5689 99.23061 127.8338 0.5048846 1.143482 0.36538 4.033877 7.569916 1.182530 1.570327 0.565852 -2.668156 0.03725000 0.076475 0.009150 -0.067325 0.01468779 0.01468779 FALSE TRUE
MSTRG.2107.3 ENSG00000186517 No_inf pgKDN_inf ARHGAP30 protein_coding   118.5689 99.23061 127.8338 0.5048846 1.143482 0.36538 9.316216 4.597714 13.283195 3.313591 5.347503 1.528565 0.07612500 0.046000 0.104025 0.058025 0.80670460 0.01468779 FALSE TRUE
MSTRG.2107.4 ENSG00000186517 No_inf pgKDN_inf ARHGAP30 protein_coding   118.5689 99.23061 127.8338 0.5048846 1.143482 0.36538 12.209567 9.117959 12.265402 1.905114 2.363941 0.427406 0.10219167 0.091725 0.096250 0.004525 0.98670488 0.01468779 FALSE TRUE
MSTRG.2107.5 ENSG00000186517 No_inf pgKDN_inf ARHGAP30 protein_coding   118.5689 99.23061 127.8338 0.5048846 1.143482 0.36538 10.860511 14.785070 5.628037 3.699835 4.439910 -1.391852 0.09594167 0.149325 0.043575 -0.105750 0.22981057 0.01468779 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000186517 E001 0.1271363 1.234239e-02 4.559883e-01   1 161046865 161046879 15 - 0.000 0.103 10.087
ENSG00000186517 E002 0.2539903 1.601567e-02 1.910242e-01   1 161046880 161046893 14 - 0.000 0.187 13.051
ENSG00000186517 E003 0.3808443 2.814346e-02 7.663896e-02   1 161046894 161046941 48 - 0.000 0.256 13.441
ENSG00000186517 E004 0.4986009 2.266064e-02 2.483037e-01   1 161046942 161046945 4 - 0.088 0.256 1.851
ENSG00000186517 E005 0.6156049 1.574131e-02 5.310434e-01 7.817801e-01 1 161046946 161046946 1 - 0.160 0.256 0.851
ENSG00000186517 E006 1.4877812 9.293542e-03 1.527982e-01 4.169712e-01 1 161046947 161046947 1 - 0.277 0.498 1.266
ENSG00000186517 E007 1.9690079 8.679261e-03 4.143340e-01 6.946193e-01 1 161046948 161046948 1 - 0.409 0.533 0.628
ENSG00000186517 E008 2.4665738 3.920582e-02 2.519769e-01 5.432354e-01 1 161046949 161046955 7 - 0.445 0.625 0.851
ENSG00000186517 E009 1092.6243448 6.443486e-04 1.140958e-07 6.574403e-06 1 161046956 161048355 1400 - 3.008 3.070 0.208
ENSG00000186517 E010 155.5085779 1.243079e-04 6.532371e-01 8.542397e-01 1 161048356 161048488 133 - 2.185 2.204 0.063
ENSG00000186517 E011 176.6163900 9.913761e-05 6.248463e-02 2.511676e-01 1 161048489 161048650 162 - 2.264 2.231 -0.113
ENSG00000186517 E012 164.5394865 1.230493e-04 4.101299e-01 6.921467e-01 1 161048651 161048789 139 - 2.224 2.212 -0.037
ENSG00000186517 E013 140.1106884 2.474002e-04 5.517986e-02 2.340039e-01 1 161048790 161048988 199 - 2.168 2.127 -0.139
ENSG00000186517 E014 121.7736323 1.432233e-04 2.169124e-01 5.031590e-01 1 161048989 161049334 346 - 2.100 2.075 -0.086
ENSG00000186517 E015 5.3850423 1.361040e-02 6.819815e-06 2.448868e-04 1 161049335 161049423 89 - 0.445 1.017 2.395
ENSG00000186517 E016 69.2227636 2.076549e-04 1.891845e-01 4.677491e-01 1 161049424 161049594 171 - 1.864 1.824 -0.133
ENSG00000186517 E017 59.2160529 3.322437e-04 2.063898e-01 4.899826e-01 1 161049595 161049689 95 - 1.798 1.757 -0.141
ENSG00000186517 E018 32.5490204 3.982897e-03 1.533352e-17 3.281737e-15 1 161049690 161051313 1624 - 1.197 1.727 1.828
ENSG00000186517 E019 232.6961089 8.859713e-05 1.232982e-03 1.758784e-02 1 161051314 161051715 402 - 2.393 2.338 -0.183
ENSG00000186517 E020 69.3012793 2.607892e-03 4.873239e-01 7.508879e-01 1 161052286 161052363 78 - 1.856 1.835 -0.071
ENSG00000186517 E021 0.3730368 1.662608e-02 4.863791e-01   1 161052364 161052439 76 - 0.088 0.187 1.265
ENSG00000186517 E022 85.4466362 6.971290e-04 7.613562e-01 9.068280e-01 1 161052440 161052543 104 - 1.937 1.935 -0.007
ENSG00000186517 E023 106.2054429 9.093126e-04 9.584018e-01 9.900487e-01 1 161052626 161052797 172 - 2.025 2.035 0.033
ENSG00000186517 E024 7.0675879 3.068414e-03 1.958879e-03 2.516991e-02 1 161052798 161053257 460 - 0.719 1.049 1.266
ENSG00000186517 E025 62.9214229 3.625414e-03 9.882156e-02 3.281114e-01 1 161053258 161053374 117 - 1.835 1.769 -0.225
ENSG00000186517 E026 25.0511153 2.944369e-02 3.331873e-01 6.252435e-01 1 161053375 161053385 11 - 1.458 1.362 -0.332
ENSG00000186517 E027 36.3807350 2.267410e-02 3.550107e-01 6.447604e-01 1 161054366 161054401 36 - 1.608 1.528 -0.272
ENSG00000186517 E028 45.1787565 7.010580e-03 2.386955e-02 1.414393e-01 1 161054402 161054473 72 - 1.717 1.595 -0.414
ENSG00000186517 E029 59.9915159 2.511054e-04 7.376006e-01 8.959078e-01 1 161054623 161054705 83 - 1.774 1.796 0.071
ENSG00000186517 E030 53.4963057 3.428246e-04 8.466514e-01 9.456191e-01 1 161056388 161056447 60 - 1.728 1.744 0.054
ENSG00000186517 E031 57.6939592 2.906347e-04 6.007091e-02 2.459100e-01 1 161056448 161056528 81 - 1.798 1.731 -0.226
ENSG00000186517 E032 25.9823285 5.212868e-04 1.867743e-02 1.212942e-01 1 161056529 161056532 4 - 1.487 1.357 -0.450
ENSG00000186517 E033 64.9297186 2.621619e-04 7.174497e-03 6.410625e-02 1 161059614 161059716 103 - 1.860 1.767 -0.315
ENSG00000186517 E034 1.7573192 1.463688e-02 2.376420e-03 2.900427e-02 1 161060156 161060262 107 - 0.160 0.625 2.850
ENSG00000186517 E035 1.0051969 8.342827e-02 2.312964e-02 1.387007e-01 1 161060263 161060439 177 - 0.088 0.459 3.073
ENSG00000186517 E036 62.8660994 2.500782e-03 2.271048e-02 1.371939e-01 1 161069528 161069619 92 - 1.845 1.754 -0.306
ENSG00000186517 E037 50.5254423 4.935924e-03 2.405435e-02 1.420194e-01 1 161069620 161069970 351 - 1.759 1.651 -0.369

Help

Please Click HERE to learn more details about the results from DEXseq.