ENSG00000186815

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000335509 ENSG00000186815 No_inf pgKDN_inf TPCN1 protein_coding protein_coding 39.03778 33.25591 34.09847 1.386986 1.407552 0.03608563 5.611890 0.0000000 11.3780174 0.0000000 1.0213379 10.1533009 0.15189167 0.000000 0.337900 0.337900 4.666524e-16 4.666524e-16 FALSE TRUE
ENST00000392569 ENSG00000186815 No_inf pgKDN_inf TPCN1 protein_coding protein_coding 39.03778 33.25591 34.09847 1.386986 1.407552 0.03608563 3.176575 0.9192756 3.4377917 0.9192756 2.1009088 1.8914943 0.07472500 0.028200 0.098375 0.070175 7.983911e-01 4.666524e-16 FALSE TRUE
ENST00000546787 ENSG00000186815 No_inf pgKDN_inf TPCN1 protein_coding protein_coding_CDS_not_defined 39.03778 33.25591 34.09847 1.386986 1.407552 0.03608563 8.171233 7.2479139 5.3011140 0.5349021 0.4092602 -0.4505405 0.20535000 0.218775 0.155675 -0.063100 6.858317e-01 4.666524e-16 FALSE TRUE
ENST00000550543 ENSG00000186815 No_inf pgKDN_inf TPCN1 protein_coding retained_intron 39.03778 33.25591 34.09847 1.386986 1.407552 0.03608563 1.471708 2.7390054 0.7263375 0.8436465 0.7263375 -1.9004706 0.04168333 0.083575 0.021425 -0.062150 1.955641e-01 4.666524e-16   FALSE
ENST00000550785 ENSG00000186815 No_inf pgKDN_inf TPCN1 protein_coding protein_coding 39.03778 33.25591 34.09847 1.386986 1.407552 0.03608563 6.905221 5.2280548 6.6493979 0.7378487 1.0280106 0.3463606 0.17725833 0.156000 0.195125 0.039125 8.416694e-01 4.666524e-16 FALSE TRUE
ENST00000551127 ENSG00000186815 No_inf pgKDN_inf TPCN1 protein_coding retained_intron 39.03778 33.25591 34.09847 1.386986 1.407552 0.03608563 2.734343 3.7613907 1.8672954 0.3123450 0.2426054 -1.0064409 0.07340000 0.113200 0.055100 -0.058100 4.248201e-01 4.666524e-16 TRUE TRUE
MSTRG.7244.11 ENSG00000186815 No_inf pgKDN_inf TPCN1 protein_coding   39.03778 33.25591 34.09847 1.386986 1.407552 0.03608563 4.739115 4.2019497 2.1334863 0.7343974 0.9123171 -0.9745290 0.11559167 0.128750 0.063650 -0.065100 6.461902e-01 4.666524e-16 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000186815 E001 0.0000000       12 113221050 113221073 24 +      
ENSG00000186815 E002 0.0000000       12 113221074 113221079 6 +      
ENSG00000186815 E003 0.0000000       12 113221080 113221231 152 +      
ENSG00000186815 E004 0.0000000       12 113221232 113221236 5 +      
ENSG00000186815 E005 0.0000000       12 113221237 113221378 142 +      
ENSG00000186815 E006 0.0000000       12 113221429 113221437 9 +      
ENSG00000186815 E007 0.0000000       12 113221438 113221445 8 +      
ENSG00000186815 E008 0.2543986 1.595636e-02 1.854893e-01   12 113221446 113221459 14 + 0.000 0.187 11.097
ENSG00000186815 E009 0.3730368 1.675971e-02 4.756292e-01   12 113221460 113221463 4 + 0.087 0.187 1.270
ENSG00000186815 E010 0.7460735 1.776591e-01 3.544824e-01 6.442246e-01 12 113221464 113221485 22 + 0.160 0.317 1.270
ENSG00000186815 E011 4.6162369 6.506841e-02 5.947851e-01 8.217649e-01 12 113221486 113221583 98 + 0.787 0.702 -0.347
ENSG00000186815 E012 6.1941042 2.699556e-03 3.801914e-01 6.667500e-01 12 113221584 113221626 43 + 0.898 0.805 -0.362
ENSG00000186815 E013 2.4589262 5.750656e-03 3.950116e-01 6.797879e-01 12 113225244 113225245 2 + 0.478 0.597 0.560
ENSG00000186815 E014 4.5551315 3.164450e-03 1.710748e-01 4.434652e-01 12 113225246 113225336 91 + 0.660 0.822 0.662
ENSG00000186815 E015 16.5021602 2.561077e-03 7.067539e-02 2.692524e-01 12 113226728 113226964 237 + 1.300 1.168 -0.467
ENSG00000186815 E016 0.3716209 1.675566e-02 4.756494e-01   12 113232549 113232607 59 + 0.087 0.187 1.270
ENSG00000186815 E017 0.1176306 1.169100e-02 6.456643e-01   12 113244261 113244361 101 + 0.087 0.000 -12.819
ENSG00000186815 E018 0.3724725 1.678526e-02 4.755138e-01   12 113244368 113244502 135 + 0.087 0.187 1.270
ENSG00000186815 E019 0.7456353 1.369722e-01 3.575816e-01 6.471965e-01 12 113244503 113244743 241 + 0.160 0.317 1.270
ENSG00000186815 E020 0.7443753 1.406872e-02 2.989980e-01 5.918772e-01 12 113245912 113246063 152 + 0.160 0.317 1.270
ENSG00000186815 E021 0.1268540 1.224310e-02 4.467786e-01   12 113260302 113260367 66 + 0.000 0.103 12.415
ENSG00000186815 E022 11.9569620 1.192329e-03 9.219131e-01 9.757480e-01 12 113260368 113260492 125 + 1.115 1.108 -0.025
ENSG00000186815 E023 15.0449632 1.601172e-03 5.720177e-01 8.081520e-01 12 113266180 113266356 177 + 1.184 1.227 0.153
ENSG00000186815 E024 11.0561021 5.259217e-03 2.883831e-01 5.819671e-01 12 113267843 113267956 114 + 1.122 1.028 -0.341
ENSG00000186815 E025 21.7121413 7.473053e-04 2.154098e-02 1.329735e-01 12 113268742 113268872 131 + 1.418 1.273 -0.506
ENSG00000186815 E026 19.1362344 7.310359e-04 1.151691e-02 8.828215e-02 12 113269757 113269845 89 + 1.375 1.206 -0.595
ENSG00000186815 E027 13.0650100 4.809179e-03 2.586260e-02 1.486422e-01 12 113272658 113272692 35 + 1.226 1.039 -0.670
ENSG00000186815 E028 15.7150616 9.810943e-04 4.538521e-03 4.628684e-02 12 113273232 113273290 59 + 1.309 1.099 -0.746
ENSG00000186815 E029 18.7118935 7.400379e-04 1.084105e-01 3.453563e-01 12 113273569 113273668 100 + 1.341 1.234 -0.378
ENSG00000186815 E030 0.0000000       12 113276918 113276918 1 +      
ENSG00000186815 E031 13.4847037 1.012952e-03 1.595009e-01 4.268817e-01 12 113276919 113277002 84 + 1.208 1.099 -0.391
ENSG00000186815 E032 8.1106206 1.667244e-03 6.836726e-02 2.638988e-01 12 113277003 113277035 33 + 1.034 0.856 -0.666
ENSG00000186815 E033 5.6316182 2.605403e-03 6.423920e-04 1.059534e-02 12 113277240 113277252 13 + 0.966 0.567 -1.617
ENSG00000186815 E034 16.7220845 1.009486e-03 3.046111e-02 1.642069e-01 12 113277253 113277364 112 + 1.314 1.160 -0.545
ENSG00000186815 E035 9.7303852 1.783359e-02 5.091014e-01 7.670898e-01 12 113278189 113278237 49 + 1.060 0.994 -0.240
ENSG00000186815 E036 9.9304633 1.471766e-03 6.797516e-02 2.631287e-01 12 113278772 113278835 64 + 1.108 0.944 -0.600
ENSG00000186815 E037 6.7122190 2.120090e-03 9.930287e-01 1.000000e+00 12 113280151 113280195 45 + 0.886 0.888 0.007
ENSG00000186815 E038 2.2248820 1.555827e-01 3.286833e-01 6.211573e-01 12 113280196 113280314 119 + 0.408 0.597 0.923
ENSG00000186815 E039 12.3197496 1.843066e-03 9.749808e-01 9.954114e-01 12 113284581 113284624 44 + 1.122 1.126 0.012
ENSG00000186815 E040 10.8786408 1.345476e-03 5.830340e-01 8.143312e-01 12 113284625 113284637 13 + 1.051 1.099 0.173
ENSG00000186815 E041 0.6256424 1.506875e-02 1.181576e-01 3.630969e-01 12 113284716 113284717 2 + 0.087 0.317 2.270
ENSG00000186815 E042 14.4818486 9.666410e-04 4.620122e-01 7.325640e-01 12 113284718 113284771 54 + 1.214 1.160 -0.195
ENSG00000186815 E043 22.0162500 4.134992e-03 2.014405e-01 4.838771e-01 12 113285889 113285961 73 + 1.399 1.314 -0.295
ENSG00000186815 E044 27.7835865 1.949416e-02 5.926985e-02 2.443386e-01 12 113286987 113287094 108 + 1.523 1.373 -0.518
ENSG00000186815 E045 2.1402063 8.016007e-03 2.496233e-04 5.019830e-03 12 113287095 113287404 310 + 0.160 0.702 3.177
ENSG00000186815 E046 19.3168702 3.787401e-03 6.242538e-01 8.383800e-01 12 113288163 113288234 72 + 1.290 1.326 0.124
ENSG00000186815 E047 5.7304510 2.590548e-03 1.027687e-04 2.427825e-03 12 113288235 113288494 260 + 0.565 1.006 1.773
ENSG00000186815 E048 2.0146408 4.538719e-02 1.144352e-03 1.660911e-02 12 113288495 113288526 32 + 0.160 0.678 3.077
ENSG00000186815 E049 3.1644064 4.750862e-02 7.748525e-07 3.711447e-05 12 113288527 113288596 70 + 0.087 0.872 4.855
ENSG00000186815 E050 6.5028714 2.161259e-03 9.944862e-07 4.639846e-05 12 113288597 113288757 161 + 0.538 1.080 2.168
ENSG00000186815 E051 20.8232741 6.649004e-04 3.883503e-01 6.742023e-01 12 113288758 113288847 90 + 1.363 1.309 -0.189
ENSG00000186815 E052 0.2543986 1.595636e-02 1.854893e-01   12 113290049 113290127 79 + 0.000 0.187 13.360
ENSG00000186815 E053 23.5137013 5.646990e-04 5.052584e-01 7.641303e-01 12 113290128 113290243 116 + 1.407 1.368 -0.136
ENSG00000186815 E054 15.7794479 8.791454e-04 5.448929e-01 7.910820e-01 12 113290952 113290998 47 + 1.202 1.247 0.158
ENSG00000186815 E055 17.1112271 8.336278e-04 6.792560e-01 8.674905e-01 12 113291609 113291677 69 + 1.243 1.273 0.105
ENSG00000186815 E056 0.3731628 1.670927e-01 5.128953e-01   12 113291678 113291873 196 + 0.087 0.187 1.270
ENSG00000186815 E057 21.3712385 9.062707e-04 2.356435e-02 1.403468e-01 12 113291874 113291958 85 + 1.275 1.419 0.503
ENSG00000186815 E058 15.5096835 9.696849e-04 1.061275e-06 4.908990e-05 12 113291959 113292933 975 + 1.006 1.373 1.305
ENSG00000186815 E059 16.8729430 8.999992e-04 5.681274e-01 8.057161e-01 12 113292934 113293018 85 + 1.232 1.273 0.145
ENSG00000186815 E060 12.2120873 1.156926e-03 9.037925e-01 9.690691e-01 12 113293019 113293073 55 + 1.115 1.126 0.039
ENSG00000186815 E061 16.8231333 8.867846e-04 7.802794e-01 9.152660e-01 12 113293269 113293349 81 + 1.259 1.240 -0.066
ENSG00000186815 E062 1.9800518 2.162984e-02 1.889413e-01 4.675334e-01 12 113294106 113294228 123 + 0.369 0.567 1.007
ENSG00000186815 E063 390.4486510 6.654975e-05 3.620616e-02 1.827553e-01 12 113295960 113298610 2651 + 2.580 2.605 0.086

Help

Please Click HERE to learn more details about the results from DEXseq.