ENSG00000186908

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000426126 ENSG00000186908 No_inf pgKDN_inf ZDHHC17 protein_coding protein_coding 17.46292 20.90421 15.80405 1.713342 1.07362 -0.4032772 3.4953521 2.496650 2.3367009 0.9292084 0.5486429 -0.09512635 0.21784167 0.130875 0.155950 0.025075 8.847642e-01 4.809737e-05 FALSE TRUE
ENST00000547604 ENSG00000186908 No_inf pgKDN_inf ZDHHC17 protein_coding nonsense_mediated_decay 17.46292 20.90421 15.80405 1.713342 1.07362 -0.4032772 0.8756803 0.000000 0.0000000 0.0000000 0.0000000 0.00000000 0.05360833 0.000000 0.000000 0.000000   4.809737e-05 FALSE FALSE
ENST00000549010 ENSG00000186908 No_inf pgKDN_inf ZDHHC17 protein_coding protein_coding_CDS_not_defined 17.46292 20.90421 15.80405 1.713342 1.07362 -0.4032772 1.0181092 1.768516 0.5945754 0.5381057 0.3834112 -1.55667951 0.05628333 0.084075 0.037700 -0.046375 6.949971e-01 4.809737e-05   FALSE
ENST00000550163 ENSG00000186908 No_inf pgKDN_inf ZDHHC17 protein_coding nonsense_mediated_decay 17.46292 20.90421 15.80405 1.713342 1.07362 -0.4032772 0.5513067 0.000000 1.6539200 0.0000000 1.6539200 7.37844222 0.02985833 0.000000 0.089575 0.089575 8.290051e-01 4.809737e-05 FALSE FALSE
ENST00000550244 ENSG00000186908 No_inf pgKDN_inf ZDHHC17 protein_coding retained_intron 17.46292 20.90421 15.80405 1.713342 1.07362 -0.4032772 1.3094019 3.218553 0.0000000 0.5299512 0.0000000 -8.33474393 0.06959167 0.157675 0.000000 -0.157675 4.809737e-05 4.809737e-05 FALSE TRUE
ENST00000552693 ENSG00000186908 No_inf pgKDN_inf ZDHHC17 protein_coding retained_intron 17.46292 20.90421 15.80405 1.713342 1.07362 -0.4032772 1.9958352 3.038605 1.3496636 0.1130171 0.1784899 -1.16489963 0.11257500 0.147425 0.085700 -0.061725 6.125576e-01 4.809737e-05   FALSE
MSTRG.6885.14 ENSG00000186908 No_inf pgKDN_inf ZDHHC17 protein_coding   17.46292 20.90421 15.80405 1.713342 1.07362 -0.4032772 1.3239702 1.812710 1.6461903 0.7007166 1.4895702 -0.13821690 0.07200000 0.092825 0.090275 -0.002550 8.159843e-01 4.809737e-05 FALSE TRUE
MSTRG.6885.16 ENSG00000186908 No_inf pgKDN_inf ZDHHC17 protein_coding   17.46292 20.90421 15.80405 1.713342 1.07362 -0.4032772 4.5922958 5.261593 5.7476039 1.9243565 0.9916953 0.12722956 0.26017500 0.239800 0.374100 0.134300 8.099013e-01 4.809737e-05 FALSE FALSE
MSTRG.6885.5 ENSG00000186908 No_inf pgKDN_inf ZDHHC17 protein_coding   17.46292 20.90421 15.80405 1.713342 1.07362 -0.4032772 1.6220156 1.849901 2.4753924 1.3847496 1.0512013 0.41824785 0.09198333 0.076050 0.166650 0.090600 8.069323e-01 4.809737e-05 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000186908 E001 0.0000000       12 76764103 76764108 6 +      
ENSG00000186908 E002 0.1271363 0.012298693 0.780479093   12 76764109 76764114 6 + 0.000 0.081 9.818
ENSG00000186908 E003 0.1271363 0.012298693 0.780479093   12 76764115 76764195 81 + 0.000 0.081 11.946
ENSG00000186908 E004 0.1265070 0.012298340 0.780383032   12 76764196 76764222 27 + 0.000 0.081 11.946
ENSG00000186908 E005 0.1265070 0.012298340 0.780383032   12 76764223 76764243 21 + 0.000 0.081 11.946
ENSG00000186908 E006 0.1265070 0.012298340 0.780383032   12 76764244 76764252 9 + 0.000 0.081 11.946
ENSG00000186908 E007 0.1265070 0.012298340 0.780383032   12 76764253 76764253 1 + 0.000 0.081 11.946
ENSG00000186908 E008 0.2435110 0.016210521 0.776379140   12 76764254 76764257 4 + 0.112 0.081 -0.520
ENSG00000186908 E009 2.2297973 0.006722833 0.510676959 0.76808754 12 76764258 76764297 40 + 0.441 0.538 0.480
ENSG00000186908 E010 2.4756978 0.006070199 0.588978300 0.81775238 12 76764298 76764329 32 + 0.485 0.563 0.373
ENSG00000186908 E011 0.0000000       12 76764573 76764812 240 +      
ENSG00000186908 E012 0.0000000       12 76769073 76769201 129 +      
ENSG00000186908 E013 0.1271363 0.012298693 0.780479093   12 76781625 76781628 4 + 0.000 0.081 11.946
ENSG00000186908 E014 0.0000000       12 76781629 76781683 55 +      
ENSG00000186908 E015 4.5742935 0.004524660 0.702473550 0.87897199 12 76797434 76797518 85 + 0.708 0.756 0.196
ENSG00000186908 E016 1.8453634 0.067247880 0.689874813 0.87258057 12 76797519 76797537 19 + 0.485 0.421 -0.328
ENSG00000186908 E017 4.8148072 0.048779970 0.974149926 0.99538773 12 76805317 76805439 123 + 0.755 0.756 0.003
ENSG00000186908 E018 3.2155125 0.007236304 0.513612823 0.77039781 12 76809043 76809120 78 + 0.561 0.651 0.398
ENSG00000186908 E019 1.9631926 0.169847891 0.925700938 0.97772510 12 76809713 76809734 22 + 0.484 0.453 -0.156
ENSG00000186908 E020 3.0889497 0.084956040 0.640098441 0.84708795 12 76809735 76809779 45 + 0.561 0.631 0.312
ENSG00000186908 E021 4.6462881 0.003115145 0.149972908 0.41248206 12 76809780 76809857 78 + 0.836 0.670 -0.672
ENSG00000186908 E022 0.0000000       12 76813313 76813449 137 +      
ENSG00000186908 E023 3.9815509 0.162382684 0.035938845 0.18185125 12 76815146 76815210 65 + 0.889 0.483 -1.721
ENSG00000186908 E024 2.0539006 0.318414023 0.315444592 0.60835450 12 76815857 76815897 41 + 0.625 0.347 -1.393
ENSG00000186908 E025 4.7523393 0.003532161 0.054593424 0.23279626 12 76815898 76816019 122 + 0.872 0.651 -0.892
ENSG00000186908 E026 1.2506242 0.065035302 0.183347937 0.46015298 12 76821058 76821129 72 + 0.200 0.421 1.480
ENSG00000186908 E027 0.8794452 0.149710442 0.181739660 0.45773544 12 76821130 76821167 38 + 0.112 0.348 2.065
ENSG00000186908 E028 5.7622409 0.022292070 0.319826926 0.61262015 12 76822406 76822531 126 + 0.889 0.771 -0.458
ENSG00000186908 E029 1.4626963 0.077830542 0.279461863 0.57275101 12 76826908 76826917 10 + 0.485 0.306 -1.006
ENSG00000186908 E030 6.8552462 0.002589350 0.104546441 0.33792447 12 76826918 76827050 133 + 0.978 0.814 -0.623
ENSG00000186908 E031 7.8562453 0.068669820 0.373611291 0.66138285 12 76828390 76828490 101 + 1.004 0.889 -0.430
ENSG00000186908 E032 1.4769535 0.009920840 0.961309381 0.99148828 12 76840059 76840297 239 + 0.392 0.386 -0.034
ENSG00000186908 E033 0.7538164 0.014947796 0.209534376 0.49392601 12 76840298 76840390 93 + 0.112 0.306 1.802
ENSG00000186908 E034 1.2520704 0.010101570 0.161972924 0.43029493 12 76840391 76840483 93 + 0.200 0.421 1.480
ENSG00000186908 E035 0.2543986 0.016004733 0.395645035   12 76840965 76841106 142 + 0.000 0.149 12.864
ENSG00000186908 E036 4.3252137 0.062025563 0.971989510 0.99474919 12 76841982 76842024 43 + 0.708 0.724 0.065
ENSG00000186908 E037 7.1316436 0.012656814 0.573436148 0.80884236 12 76842025 76842106 82 + 0.936 0.877 -0.220
ENSG00000186908 E038 6.2284336 0.002991751 0.088166257 0.30793673 12 76842919 76842981 63 + 0.950 0.771 -0.690
ENSG00000186908 E039 1.8345060 0.013084802 0.343243603 0.63442428 12 76842982 76843069 88 + 0.524 0.386 -0.712
ENSG00000186908 E040 11.0732340 0.001299739 0.011303645 0.08719262 12 76843914 76844874 961 + 0.920 1.149 0.836
ENSG00000186908 E041 2.2032644 0.006236472 0.443481382 0.71832317 12 76844875 76844947 73 + 0.561 0.453 -0.520
ENSG00000186908 E042 10.5823062 0.001304044 0.007327103 0.06512525 12 76844948 76845708 761 + 0.889 1.136 0.911
ENSG00000186908 E043 9.1519782 0.003201926 0.438282858 0.71449485 12 76845709 76845802 94 + 0.950 1.026 0.280
ENSG00000186908 E044 1.2688803 0.009801100 0.002803303 0.03278260 12 76846291 76846595 305 + 0.000 0.483 14.853
ENSG00000186908 E045 6.9682667 0.002036086 0.054859350 0.23328741 12 76846596 76846679 84 + 0.755 0.963 0.802
ENSG00000186908 E046 4.1916229 0.006108113 0.979654331 0.99760412 12 76848233 76848237 5 + 0.708 0.707 -0.005
ENSG00000186908 E047 12.8059880 0.001291570 0.780096816 0.91525707 12 76848238 76848390 153 + 1.143 1.123 -0.072
ENSG00000186908 E048 9.3079341 0.001545656 0.111716299 0.35108419 12 76849376 76849470 95 + 1.084 0.943 -0.520
ENSG00000186908 E049 0.3811266 0.022971920 0.196976655   12 76849471 76849669 199 + 0.000 0.208 13.375
ENSG00000186908 E050 178.6307843 0.002858788 0.718129704 0.88657055 12 76850847 76853696 2850 + 2.239 2.248 0.031

Help

Please Click HERE to learn more details about the results from DEXseq.