ENSG00000187555

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000381886 ENSG00000187555 No_inf pgKDN_inf USP7 protein_coding protein_coding 59.77422 60.6156 64.11074 4.361733 2.383589 0.08086408 3.602699 0.000000 8.011368 0.0000000 1.081420 9.6477044 0.05853333 0.00000 0.12570 0.12570 1.893197e-11 1.893197e-11 FALSE TRUE
ENST00000563961 ENSG00000187555 No_inf pgKDN_inf USP7 protein_coding nonsense_mediated_decay 59.77422 60.6156 64.11074 4.361733 2.383589 0.08086408 3.754238 1.727682 6.164711 0.9986102 1.068854 1.8292076 0.06228333 0.03000 0.09550 0.06550 3.674590e-01 1.893197e-11 FALSE TRUE
ENST00000565883 ENSG00000187555 No_inf pgKDN_inf USP7 protein_coding retained_intron 59.77422 60.6156 64.11074 4.361733 2.383589 0.08086408 2.938498 6.283404 2.532090 2.1914712 1.504710 -1.3078256 0.04545000 0.09920 0.03715 -0.06205 4.676784e-01 1.893197e-11 FALSE FALSE
ENST00000567113 ENSG00000187555 No_inf pgKDN_inf USP7 protein_coding retained_intron 59.77422 60.6156 64.11074 4.361733 2.383589 0.08086408 1.559698 4.161887 0.000000 2.6928451 0.000000 -8.7045564 0.02744167 0.07325 0.00000 -0.07325 4.975082e-01 1.893197e-11   FALSE
MSTRG.10611.3 ENSG00000187555 No_inf pgKDN_inf USP7 protein_coding   59.77422 60.6156 64.11074 4.361733 2.383589 0.08086408 36.025069 32.514395 38.199492 0.1365480 2.045986 0.2324089 0.61026667 0.54425 0.60010 0.05585 8.281822e-01 1.893197e-11 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000187555 E001 10.0378581 0.0549679839 8.871441e-03 7.421627e-02 16 8892097 8892771 675 - 0.844 1.193 1.288
ENSG00000187555 E002 203.3520666 0.0001020210 3.310448e-07 1.716786e-05 16 8892772 8893787 1016 - 2.257 2.362 0.348
ENSG00000187555 E003 77.3001169 0.0047020404 1.980857e-01 4.794943e-01 16 8893788 8893939 152 - 1.866 1.922 0.187
ENSG00000187555 E004 97.3468366 0.0001828354 4.073615e-03 4.297855e-02 16 8893940 8894104 165 - 1.949 2.036 0.291
ENSG00000187555 E005 69.6381575 0.0005959640 3.948048e-01 6.796056e-01 16 8894550 8894640 91 - 1.833 1.865 0.105
ENSG00000187555 E006 51.8806865 0.0037934447 8.212096e-01 9.350721e-01 16 8894784 8894855 72 - 1.717 1.728 0.036
ENSG00000187555 E007 31.2294818 0.0077455100 8.311042e-01 9.389900e-01 16 8895031 8895044 14 - 1.514 1.499 -0.052
ENSG00000187555 E008 30.8866315 0.0093314170 9.666744e-01 9.933055e-01 16 8895045 8895058 14 - 1.502 1.503 0.001
ENSG00000187555 E009 36.0509463 0.0145337713 1.274441e-01 3.785214e-01 16 8895059 8895083 25 - 1.517 1.619 0.346
ENSG00000187555 E010 49.6632979 0.0003266947 1.899870e-01 4.689377e-01 16 8895084 8895150 67 - 1.677 1.732 0.188
ENSG00000187555 E011 59.9246040 0.0002472496 1.632097e-01 4.318787e-01 16 8895642 8895741 100 - 1.758 1.812 0.182
ENSG00000187555 E012 49.2908076 0.0002945426 1.764341e-01 4.505800e-01 16 8896999 8897063 65 - 1.673 1.730 0.195
ENSG00000187555 E013 37.7587274 0.0004618074 5.805928e-01 8.129737e-01 16 8897064 8897099 36 - 1.575 1.601 0.091
ENSG00000187555 E014 0.4984749 0.0336340025 2.369510e-01   16 8897100 8897254 155 - 0.087 0.258 1.873
ENSG00000187555 E015 45.1309620 0.0003370069 8.687837e-01 9.548707e-01 16 8898360 8898437 78 - 1.667 1.659 -0.026
ENSG00000187555 E016 1.3671255 0.0732246543 9.342121e-02 3.177711e-01 16 8898438 8898530 93 - 0.221 0.500 1.702
ENSG00000187555 E017 46.7016960 0.0003444905 8.026274e-01 9.264812e-01 16 8898531 8898593 63 - 1.683 1.672 -0.038
ENSG00000187555 E018 42.6049054 0.0003315762 7.589167e-01 9.053720e-01 16 8898594 8898639 46 - 1.632 1.646 0.047
ENSG00000187555 E019 0.6237260 0.0598604817 1.243968e-01 3.737518e-01 16 8898640 8898720 81 - 0.087 0.318 2.288
ENSG00000187555 E020 26.7339872 0.0117262353 1.819599e-01 4.579766e-01 16 8899121 8899149 29 - 1.484 1.390 -0.324
ENSG00000187555 E021 26.4633388 0.0048263999 9.278940e-01 9.786230e-01 16 8899150 8899174 25 - 1.441 1.435 -0.019
ENSG00000187555 E022 21.8145271 0.0126905330 8.491023e-01 9.464293e-01 16 8899175 8899188 14 - 1.365 1.350 -0.052
ENSG00000187555 E023 1.3801528 0.0395689897 1.677389e-02 1.129717e-01 16 8899307 8899579 273 - 0.159 0.536 2.457
ENSG00000187555 E024 0.8714819 0.0131982167 1.621696e-01 4.306478e-01 16 8899580 8899603 24 - 0.159 0.371 1.609
ENSG00000187555 E025 57.2471235 0.0003599589 7.233017e-01 8.888660e-01 16 8899604 8899757 154 - 1.758 1.772 0.047
ENSG00000187555 E026 2.4934442 0.0056786267 7.138468e-03 6.386963e-02 16 8899758 8900131 374 - 0.324 0.704 1.873
ENSG00000187555 E027 46.1327080 0.0012114347 1.296826e-01 3.820188e-01 16 8900530 8900630 101 - 1.639 1.708 0.234
ENSG00000187555 E028 2.3232235 0.0060307247 8.401232e-01 9.425882e-01 16 8900631 8900920 290 - 0.507 0.536 0.136
ENSG00000187555 E029 38.9432402 0.0003614349 7.643629e-02 2.826932e-01 16 8900990 8901057 68 - 1.559 1.643 0.288
ENSG00000187555 E030 45.0429492 0.0003290037 9.286888e-01 9.789172e-01 16 8901142 8901234 93 - 1.660 1.664 0.013
ENSG00000187555 E031 1.2507806 0.0099090220 2.477948e-02 1.447008e-01 16 8901933 8902081 149 - 0.159 0.500 2.288
ENSG00000187555 E032 36.6689542 0.0004182634 3.849429e-01 6.711116e-01 16 8902082 8902138 57 - 1.595 1.552 -0.147
ENSG00000187555 E033 18.7986680 0.0010029448 7.911903e-01 9.199736e-01 16 8902139 8902142 4 - 1.288 1.305 0.062
ENSG00000187555 E034 30.5429196 0.0030025873 5.208190e-01 7.749780e-01 16 8902143 8902187 45 - 1.481 1.517 0.126
ENSG00000187555 E035 1.4866751 0.0471465874 1.605275e-01 4.283751e-01 16 8902188 8902380 193 - 0.276 0.500 1.288
ENSG00000187555 E036 39.5019916 0.0028047228 8.516077e-01 9.475268e-01 16 8902381 8902482 102 - 1.611 1.601 -0.034
ENSG00000187555 E037 47.0026822 0.0037784959 3.787496e-01 6.656177e-01 16 8903268 8903402 135 - 1.701 1.657 -0.149
ENSG00000187555 E038 36.6126492 0.0004425055 1.178634e-01 3.626412e-01 16 8904435 8904504 70 - 1.609 1.531 -0.265
ENSG00000187555 E039 20.5370454 0.0021408484 1.296055e-01 3.818915e-01 16 8904505 8904524 20 - 1.377 1.275 -0.354
ENSG00000187555 E040 23.7840995 0.0092678601 4.601388e-02 2.102790e-01 16 8904525 8904565 41 - 1.454 1.311 -0.497
ENSG00000187555 E041 49.1582602 0.0022252602 8.118183e-02 2.927562e-01 16 8905187 8905331 145 - 1.736 1.654 -0.277
ENSG00000187555 E042 52.2549209 0.0029620692 2.696847e-02 1.526219e-01 16 8906426 8906582 157 - 1.771 1.667 -0.354
ENSG00000187555 E043 42.7232149 0.0011056972 7.891665e-03 6.848793e-02 16 8908341 8908450 110 - 1.695 1.568 -0.432
ENSG00000187555 E044 36.9041874 0.0054474054 3.998467e-01 6.835317e-01 16 8910745 8910827 83 - 1.600 1.552 -0.164
ENSG00000187555 E045 30.5355367 0.0058687295 1.859530e-01 4.639015e-01 16 8915254 8915344 91 - 1.534 1.452 -0.283
ENSG00000187555 E046 25.7784061 0.0005590020 1.504046e-01 4.129786e-01 16 8915445 8915525 81 - 1.464 1.380 -0.292
ENSG00000187555 E047 20.4335757 0.0006436312 2.378924e-01 5.268761e-01 16 8916502 8916556 55 - 1.365 1.288 -0.269
ENSG00000187555 E048 31.3525225 0.0005060406 5.826264e-02 2.416786e-01 16 8917026 8917156 131 - 1.554 1.452 -0.349
ENSG00000187555 E049 24.8571388 0.0005784389 1.008495e-02 8.078055e-02 16 8919031 8919139 109 - 1.477 1.322 -0.536
ENSG00000187555 E050 15.9524322 0.0011578570 4.896971e-01 7.526178e-01 16 8920359 8920404 46 - 1.251 1.201 -0.179
ENSG00000187555 E051 13.9507257 0.0034663086 7.678780e-02 2.833133e-01 16 8920405 8920442 38 - 1.235 1.092 -0.510
ENSG00000187555 E052 9.6770055 0.0017426928 2.434247e-02 1.430784e-01 16 8920443 8920447 5 - 1.113 0.905 -0.767
ENSG00000187555 E053 9.5606281 0.0062346500 3.793414e-02 1.879301e-01 16 8921157 8921159 3 - 1.105 0.905 -0.740
ENSG00000187555 E054 12.9508746 0.0015326087 1.841957e-02 1.200823e-01 16 8921160 8921176 17 - 1.223 1.031 -0.692
ENSG00000187555 E055 23.5862420 0.0006874316 1.374210e-01 3.945524e-01 16 8921177 8921295 119 - 1.430 1.339 -0.316
ENSG00000187555 E056 23.0074776 0.0005876345 3.012017e-01 5.942085e-01 16 8923215 8923306 92 - 1.408 1.344 -0.221
ENSG00000187555 E057 15.7034938 0.0009151733 4.730989e-01 7.401620e-01 16 8923307 8923353 47 - 1.246 1.193 -0.186
ENSG00000187555 E058 12.6225071 0.0010398725 1.239520e-01 3.729554e-01 16 8923354 8923413 60 - 1.188 1.062 -0.449
ENSG00000187555 E059 0.5992382 0.0142508694 2.510519e-01 5.422596e-01 16 8929369 8929543 175 - 0.276 0.104 -1.712
ENSG00000187555 E060 15.8816775 0.0009889872 5.451883e-02 2.325691e-01 16 8930293 8930397 105 - 1.288 1.146 -0.502
ENSG00000187555 E061 0.1265070 0.0123600355 4.399497e-01   16 8931940 8932053 114 - 0.000 0.104 11.253
ENSG00000187555 E062 0.2362687 0.0157067127 3.185301e-01   16 8935643 8935758 116 - 0.159 0.000 -12.661
ENSG00000187555 E063 0.0000000       16 8935801 8935856 56 -      
ENSG00000187555 E064 0.0000000       16 8936583 8936729 147 -      
ENSG00000187555 E065 0.1268540 0.0123702192 4.399600e-01   16 8949554 8949653 100 - 0.000 0.104 11.253
ENSG00000187555 E066 0.0000000       16 8956308 8956380 73 -      
ENSG00000187555 E067 0.1186381 0.0118638675 6.555408e-01   16 8962476 8962612 137 - 0.087 0.000 -11.730
ENSG00000187555 E068 17.6589773 0.0249917566 3.877064e-02 1.904759e-01 16 8963207 8963906 700 - 1.352 1.154 -0.697
ENSG00000187555 E069 0.0000000       16 8964394 8964514 121 -      
ENSG00000187555 E070 0.0000000       16 8975094 8975328 235 -      

Help

Please Click HERE to learn more details about the results from DEXseq.