ENSG00000187994

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000591812 ENSG00000187994 No_inf pgKDN_inf RINL protein_coding protein_coding 6.161453 6.706428 4.558533 0.2296383 0.3065487 -0.5559632 2.9890404 2.1799819 3.7484413 0.2991942 0.2828423 0.7792155 0.52955000 0.329750 0.832325 0.502575 0.01835745 0.01835745 FALSE TRUE
ENST00000593424 ENSG00000187994 No_inf pgKDN_inf RINL protein_coding protein_coding 6.161453 6.706428 4.558533 0.2296383 0.3065487 -0.5559632 1.7933556 1.9084223 0.4899814 0.7231179 0.4899814 -1.9399741 0.26593333 0.295625 0.093150 -0.202475 0.51486984 0.01835745 FALSE FALSE
ENST00000593809 ENSG00000187994 No_inf pgKDN_inf RINL protein_coding protein_coding 6.161453 6.706428 4.558533 0.2296383 0.3065487 -0.5559632 0.1492543 0.4477629 0.0000000 0.4477629 0.0000000 -5.5165286 0.02022500 0.060675 0.000000 -0.060675 0.89157716 0.01835745   FALSE
MSTRG.15124.4 ENSG00000187994 No_inf pgKDN_inf RINL protein_coding   6.161453 6.706428 4.558533 0.2296383 0.3065487 -0.5559632 0.3223204 0.9669613 0.0000000 0.9669613 0.0000000 -6.6102295 0.04367500 0.131025 0.000000 -0.131025 0.90141699 0.01835745 FALSE FALSE
MSTRG.15124.5 ENSG00000187994 No_inf pgKDN_inf RINL protein_coding   6.161453 6.706428 4.558533 0.2296383 0.3065487 -0.5559632 0.3386145 0.6912955 0.0000000 0.6912955 0.0000000 -6.1319505 0.04794167 0.104750 0.000000 -0.104750 0.90777506 0.01835745 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000187994 E001 0.1272623 0.012645477 0.59005187   19 38867830 38867833 4 - 0.000 0.092 10.541
ENSG00000187994 E002 1.1149017 0.012580023 0.38511440 0.67121261 19 38867834 38867886 53 - 0.247 0.382 0.885
ENSG00000187994 E003 12.9795792 0.004937155 0.62348451 0.83785787 19 38867887 38868359 473 - 1.161 1.129 -0.115
ENSG00000187994 E004 20.6244704 0.003214950 0.01060573 0.08348070 19 38868360 38868981 622 - 1.244 1.398 0.535
ENSG00000187994 E005 4.0310051 0.041839210 0.47667100 0.74309258 19 38868982 38869166 185 - 0.747 0.656 -0.379
ENSG00000187994 E006 0.4886562 0.039956577 0.92524816   19 38869167 38869230 64 - 0.179 0.167 -0.115
ENSG00000187994 E007 0.1186381 0.011956103 0.48991622   19 38869231 38869246 16 - 0.099 0.000 -13.620
ENSG00000187994 E008 3.1637990 0.012183748 0.30989352 0.60316842 19 38869247 38869283 37 - 0.683 0.555 -0.563
ENSG00000187994 E009 4.2705818 0.003709224 0.42998844 0.70799233 19 38869284 38869410 127 - 0.766 0.678 -0.363
ENSG00000187994 E010 5.6763209 0.002823821 0.23064240 0.51906811 19 38869573 38869704 132 - 0.747 0.880 0.522
ENSG00000187994 E011 0.0000000       19 38869705 38869834 130 -      
ENSG00000187994 E012 0.1271363 0.012615925 0.59007001   19 38869835 38869925 91 - 0.000 0.092 12.637
ENSG00000187994 E013 4.4192440 0.004070740 0.94734313 0.98606193 19 38869943 38870069 127 - 0.727 0.738 0.045
ENSG00000187994 E014 1.4622246 0.009455111 0.46661522 0.73530139 19 38870070 38870260 191 - 0.445 0.338 -0.601
ENSG00000187994 E015 0.1265070 0.012419483 0.59038081   19 38870570 38870651 82 - 0.000 0.092 12.637
ENSG00000187994 E016 0.0000000       19 38870652 38870747 96 -      
ENSG00000187994 E017 4.6583727 0.031075064 0.79073929 0.91982600 19 38870748 38870992 245 - 0.767 0.738 -0.116
ENSG00000187994 E018 5.3274207 0.002829588 0.01326849 0.09653618 19 38871078 38871227 150 - 0.924 0.656 -1.066
ENSG00000187994 E019 0.2530140 0.162304014 0.31211831   19 38871228 38871465 238 - 0.000 0.167 13.376
ENSG00000187994 E020 0.2539903 0.016413603 0.27543493   19 38871466 38871646 181 - 0.000 0.167 13.500
ENSG00000187994 E021 2.4305033 0.006965496 0.27198281 0.56578552 19 38871647 38871711 65 - 0.608 0.460 -0.700
ENSG00000187994 E022 0.1272623 0.012645477 0.59005187   19 38871712 38871797 86 - 0.000 0.092 12.637
ENSG00000187994 E023 2.0934689 0.112023470 0.68495789 0.86966545 19 38871798 38871870 73 - 0.445 0.525 0.399
ENSG00000187994 E024 0.0000000       19 38873751 38873885 135 -      
ENSG00000187994 E025 1.8574794 0.011987357 0.26474037 0.55779776 19 38873886 38873988 103 - 0.357 0.525 0.885
ENSG00000187994 E026 1.1001379 0.011802783 0.64219933 0.84824477 19 38876331 38876474 144 - 0.357 0.288 -0.437
ENSG00000187994 E027 0.4818909 0.018299534 0.27723612   19 38876475 38876490 16 - 0.247 0.092 -1.700
ENSG00000187994 E028 0.2448930 0.016972241 0.94299973   19 38876491 38876692 202 - 0.099 0.092 -0.115
ENSG00000187994 E029 0.7264094 0.014172224 0.35351165 0.64324059 19 38876693 38876781 89 - 0.305 0.167 -1.115
ENSG00000187994 E030 0.3543453 0.015839426 0.08635305   19 38878232 38878275 44 - 0.247 0.000 -14.918

Help

Please Click HERE to learn more details about the results from DEXseq.