ENSG00000188092

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000314163 ENSG00000188092 No_inf pgKDN_inf GPR89B protein_coding protein_coding 9.011999 10.32785 9.340627 1.413919 0.7051169 -0.1448014 0.9075659 0.0000000 1.1602831 0.0000000 1.1602831 6.870714 0.10110833 0.000000 0.155175 0.155175 0.84855848 0.01760849 FALSE TRUE
ENST00000461786 ENSG00000188092 No_inf pgKDN_inf GPR89B protein_coding nonsense_mediated_decay 9.011999 10.32785 9.340627 1.413919 0.7051169 -0.1448014 0.5036062 0.0000000 0.8619594 0.0000000 0.8619594 6.446189 0.05048333 0.000000 0.089925 0.089925 0.83748868 0.01760849   TRUE
ENST00000478307 ENSG00000188092 No_inf pgKDN_inf GPR89B protein_coding retained_intron 9.011999 10.32785 9.340627 1.413919 0.7051169 -0.1448014 2.4163354 4.5552783 0.9411712 0.3454465 0.3934259 -2.262926 0.28667500 0.459725 0.099250 -0.360475 0.01760849 0.01760849 TRUE TRUE
ENST00000488165 ENSG00000188092 No_inf pgKDN_inf GPR89B protein_coding nonsense_mediated_decay 9.011999 10.32785 9.340627 1.413919 0.7051169 -0.1448014 3.3579817 2.9825691 4.8661366 1.0231708 1.5229541 0.704354 0.35591667 0.256875 0.509775 0.252900 0.71093192 0.01760849 FALSE TRUE
ENST00000488603 ENSG00000188092 No_inf pgKDN_inf GPR89B protein_coding retained_intron 9.011999 10.32785 9.340627 1.413919 0.7051169 -0.1448014 0.5624083 1.1601784 0.3222050 0.1565883 0.2027742 -1.816583 0.06372500 0.127725 0.034250 -0.093475 0.45190376 0.01760849 FALSE TRUE
ENST00000490955 ENSG00000188092 No_inf pgKDN_inf GPR89B protein_coding retained_intron 9.011999 10.32785 9.340627 1.413919 0.7051169 -0.1448014 0.6139246 1.4192907 0.1974740 0.3943742 0.1422622 -2.784297 0.06950000 0.139025 0.020675 -0.118350 0.17442580 0.01760849 FALSE TRUE
ENST00000491975 ENSG00000188092 No_inf pgKDN_inf GPR89B protein_coding nonsense_mediated_decay 9.011999 10.32785 9.340627 1.413919 0.7051169 -0.1448014 0.6501772 0.2105352 0.9913975 0.2105352 0.9913975 2.182934 0.07257500 0.016600 0.090950 0.074350 0.99564166 0.01760849 TRUE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000188092 E001 0.0000000       1 147928393 147928419 27 +      
ENSG00000188092 E002 0.7358125 0.015690376 4.754534e-01 0.742052362 1 147928420 147928435 16 + 0.294 0.192 -0.804
ENSG00000188092 E003 3.8620422 0.004267672 4.837958e-05 0.001295583 1 147928436 147928578 143 + 0.909 0.455 -1.941
ENSG00000188092 E004 0.7263755 0.152169180 1.524572e-01 0.416440945 1 147936627 147936686 60 + 0.361 0.137 -1.804
ENSG00000188092 E005 0.0000000       1 147938714 147938817 104 +      
ENSG00000188092 E006 0.0000000       1 147943438 147943544 107 +      
ENSG00000188092 E007 0.0000000       1 147943977 147943996 20 +      
ENSG00000188092 E008 0.0000000       1 147943997 147944081 85 +      
ENSG00000188092 E009 0.0000000       1 147944082 147944098 17 +      
ENSG00000188092 E010 0.0000000       1 147953345 147953432 88 +      
ENSG00000188092 E011 0.0000000       1 147953433 147953465 33 +      
ENSG00000188092 E012 0.0000000       1 147954322 147954402 81 +      
ENSG00000188092 E013 0.5074127 0.024476074 1.509098e-01 0.413785980 1 147966554 147966663 110 + 0.000 0.241 10.770
ENSG00000188092 E014 2.3752520 0.053550146 1.790965e-01 0.454138770 1 147966771 147968331 1561 + 0.360 0.577 1.103
ENSG00000188092 E015 0.0000000       1 147968332 147968357 26 +      
ENSG00000188092 E016 2.0074020 0.008872081 1.304192e-01 0.383137877 1 147968358 147968428 71 + 0.295 0.533 1.312
ENSG00000188092 E017 5.2723558 0.004166508 3.307083e-03 0.037190206 1 147968429 147968874 446 + 0.514 0.874 1.518
ENSG00000188092 E018 0.4988833 0.016177384 6.809847e-01   1 147968875 147968894 20 + 0.122 0.192 0.781
ENSG00000188092 E019 0.9989000 0.012998918 5.174615e-01 0.772946261 1 147968895 147968934 40 + 0.217 0.325 0.781
ENSG00000188092 E020 0.3812526 0.016694796 2.750186e-01   1 147968935 147968963 29 + 0.000 0.192 10.442
ENSG00000188092 E021 1.6425161 0.009897555 1.723689e-02 0.114867573 1 147968964 147969866 903 + 0.122 0.508 2.781
ENSG00000188092 E022 0.1186381 0.012243545 2.881569e-01   1 147969867 147969959 93 + 0.122 0.000 -11.066
ENSG00000188092 E023 0.0000000       1 147986199 147986294 96 +      
ENSG00000188092 E024 0.0000000       1 147988432 147988521 90 +      
ENSG00000188092 E025 0.0000000       1 147992502 147992567 66 +      
ENSG00000188092 E026 9.3438523 0.001674799 4.678054e-02 0.212392325 1 147992711 147993592 882 + 1.079 0.944 -0.499

Help

Please Click HERE to learn more details about the results from DEXseq.