ENSG00000188191

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000400758 ENSG00000188191 No_inf pgKDN_inf PRKAR1B protein_coding protein_coding 14.19735 11.23237 16.16994 2.704984 1.612679 0.5252601 3.2470840 0.19839300 4.7438152 0.19839300 0.9290444 4.5117071 0.20433333 0.014950 0.290475 0.275525 0.001760386 0.001760386 FALSE TRUE
ENST00000403562 ENSG00000188191 No_inf pgKDN_inf PRKAR1B protein_coding protein_coding 14.19735 11.23237 16.16994 2.704984 1.612679 0.5252601 0.6463296 0.06968726 1.0139731 0.06968726 0.6725401 3.6836849 0.04485833 0.008475 0.067750 0.059275 0.817908529 0.001760386 FALSE TRUE
ENST00000537384 ENSG00000188191 No_inf pgKDN_inf PRKAR1B protein_coding protein_coding 14.19735 11.23237 16.16994 2.704984 1.612679 0.5252601 3.3109031 1.57404124 3.1593768 0.56189640 0.4383574 1.0005893 0.25135000 0.187800 0.203875 0.016075 0.906701231 0.001760386 FALSE TRUE
ENST00000703504 ENSG00000188191 No_inf pgKDN_inf PRKAR1B protein_coding protein_coding_CDS_not_defined 14.19735 11.23237 16.16994 2.704984 1.612679 0.5252601 0.7797082 2.33912457 0.0000000 2.33912457 0.0000000 -7.8759794 0.04379167 0.131375 0.000000 -0.131375 0.819462967 0.001760386   FALSE
MSTRG.25713.13 ENSG00000188191 No_inf pgKDN_inf PRKAR1B protein_coding   14.19735 11.23237 16.16994 2.704984 1.612679 0.5252601 0.4298843 1.02949844 0.2601544 1.02949844 0.2601544 -1.9440317 0.03001667 0.077575 0.012475 -0.065100 0.968004951 0.001760386 FALSE FALSE
MSTRG.25713.4 ENSG00000188191 No_inf pgKDN_inf PRKAR1B protein_coding   14.19735 11.23237 16.16994 2.704984 1.612679 0.5252601 4.5217873 4.56711422 5.3670257 0.77774564 0.5713341 0.2323701 0.33906667 0.442225 0.345500 -0.096725 0.830466730 0.001760386 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000188191 E001 0.0000000       7 549197 549197 1 -      
ENSG00000188191 E002 0.0000000       7 549198 549199 2 -      
ENSG00000188191 E003 24.0870331 0.006573841 0.0488593540 0.21776594 7 549200 549741 542 - 1.337 1.463 0.436
ENSG00000188191 E004 1.9780447 0.172842232 0.1554450534 0.42130256 7 549742 549749 8 - 0.344 0.600 1.305
ENSG00000188191 E005 17.7297344 0.003068064 0.1228678375 0.37101625 7 549750 550269 520 - 1.217 1.328 0.389
ENSG00000188191 E006 15.2498982 0.001064036 0.0737091013 0.27639760 7 550270 550602 333 - 1.253 1.131 -0.432
ENSG00000188191 E007 5.9438954 0.002870141 0.5622079899 0.80212379 7 551389 551470 82 - 0.859 0.804 -0.216
ENSG00000188191 E008 10.0476260 0.001707410 0.1781728065 0.45294426 7 579256 579377 122 - 1.081 0.971 -0.406
ENSG00000188191 E009 8.0732505 0.008648587 0.0405697643 0.19538259 7 584508 584568 61 - 1.027 0.824 -0.769
ENSG00000188191 E010 4.4975747 0.003951522 0.9783955303 0.99704463 7 596146 596179 34 - 0.734 0.738 0.015
ENSG00000188191 E011 7.9663384 0.016127774 0.1670772009 0.43758613 7 596180 596232 53 - 1.002 0.861 -0.531
ENSG00000188191 E012 9.7568347 0.015350585 0.0339270810 0.17540058 7 596233 596304 72 - 1.102 0.895 -0.766
ENSG00000188191 E013 2.2970698 0.008405320 0.4135470251 0.69425235 7 601453 601540 88 - 0.558 0.445 -0.548
ENSG00000188191 E014 1.4260574 0.009678084 0.0120937776 0.09100960 7 602553 602683 131 - 0.507 0.113 -2.891
ENSG00000188191 E015 5.0008542 0.003431994 0.6806610471 0.86816715 7 606193 606239 47 - 0.750 0.804 0.214
ENSG00000188191 E016 2.0975298 0.007898737 0.1374680097 0.39464521 7 607391 607395 5 - 0.382 0.600 1.083
ENSG00000188191 E017 3.1053708 0.008766480 0.0068966104 0.06249358 7 607396 607452 57 - 0.416 0.783 1.655
ENSG00000188191 E018 0.4680160 0.761212833 0.4780358209   7 613541 613571 31 - 0.256 0.000 -12.687
ENSG00000188191 E019 0.1265070 0.012343256 0.3643120652   7 675892 675942 51 - 0.000 0.113 11.731
ENSG00000188191 E020 4.4418497 0.018908136 0.0211855943 0.13166381 7 677229 677320 92 - 0.581 0.878 1.220
ENSG00000188191 E021 6.2085857 0.035848643 0.9580683601 0.98998140 7 680556 680726 171 - 0.847 0.861 0.053
ENSG00000188191 E022 0.0000000       7 691540 691794 255 -      
ENSG00000188191 E023 0.1186381 0.011940160 0.7942528045   7 696713 697102 390 - 0.080 0.000 -10.863
ENSG00000188191 E024 0.2533610 0.016040992 0.1380740254   7 705344 705719 376 - 0.000 0.203 12.714
ENSG00000188191 E025 0.0000000       7 707287 707407 121 -      
ENSG00000188191 E026 4.4686061 0.159767218 0.3315122988 0.62363998 7 711329 711527 199 - 0.780 0.660 -0.492
ENSG00000188191 E027 0.0000000       7 712414 712572 159 -      
ENSG00000188191 E028 0.1271363 0.013078026 0.3638388823   7 712848 712921 74 - 0.000 0.113 11.731
ENSG00000188191 E029 0.0000000       7 712922 713054 133 -      
ENSG00000188191 E030 0.0000000       7 713055 713207 153 -      
ENSG00000188191 E031 0.8877537 0.012906019 0.0009530126 0.01445032 7 716619 716846 228 - 0.000 0.489 14.477
ENSG00000188191 E032 0.1265070 0.012343256 0.3643120652   7 726604 727209 606 - 0.000 0.113 11.731
ENSG00000188191 E033 0.0000000       7 727210 727341 132 -      
ENSG00000188191 E034 0.2448930 0.016617863 0.7707906763   7 727590 727650 61 - 0.080 0.113 0.568

Help

Please Click HERE to learn more details about the results from DEXseq.