ENSG00000189091

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000302516 ENSG00000189091 No_inf pgKDN_inf SF3B3 protein_coding protein_coding 67.11694 41.43282 79.00144 1.433602 2.701853 0.9309394 11.148199 6.992479 13.107577 0.4238462 0.6045819 0.9055635 0.16742500 0.170100 0.165975 -0.004125 1.0000000000 0.0001268763 FALSE  
ENST00000563739 ENSG00000189091 No_inf pgKDN_inf SF3B3 protein_coding retained_intron 67.11694 41.43282 79.00144 1.433602 2.701853 0.9309394 9.933940 5.138094 12.396567 1.3562786 2.5322639 1.2689936 0.14544167 0.126875 0.154475 0.027600 0.8461669181 0.0001268763 FALSE  
ENST00000566095 ENSG00000189091 No_inf pgKDN_inf SF3B3 protein_coding protein_coding 67.11694 41.43282 79.00144 1.433602 2.701853 0.9309394 2.917764 0.000000 4.642726 0.0000000 0.9851225 8.8619323 0.03685000 0.000000 0.060075 0.060075 0.0001268763 0.0001268763 FALSE  
ENST00000567635 ENSG00000189091 No_inf pgKDN_inf SF3B3 protein_coding nonsense_mediated_decay 67.11694 41.43282 79.00144 1.433602 2.701853 0.9309394 3.756247 4.466513 2.457769 1.8659187 1.4244048 -0.8591680 0.06511667 0.105900 0.032350 -0.073550 0.6919504420 0.0001268763    
ENST00000568539 ENSG00000189091 No_inf pgKDN_inf SF3B3 protein_coding retained_intron 67.11694 41.43282 79.00144 1.433602 2.701853 0.9309394 18.777031 12.156818 21.581297 1.5576219 1.7573698 0.8274980 0.27924167 0.291850 0.274950 -0.016900 0.9489620310 0.0001268763 FALSE  
ENST00000572365 ENSG00000189091 No_inf pgKDN_inf SF3B3 protein_coding retained_intron 67.11694 41.43282 79.00144 1.433602 2.701853 0.9309394 10.091071 3.536738 13.609829 1.2699671 1.8553328 1.9411437 0.14010833 0.084675 0.171550 0.086875 0.5713151242 0.0001268763 FALSE  
MSTRG.11430.11 ENSG00000189091 No_inf pgKDN_inf SF3B3 protein_coding   67.11694 41.43282 79.00144 1.433602 2.701853 0.9309394 4.864846 3.908514 5.107886 0.5532565 0.7715315 0.3852412 0.07639167 0.093800 0.065600 -0.028200 0.7901504009 0.0001268763 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000189091 E001 0.1170040 0.0116720130 0.881890214   16 70523791 70523812 22 + 0.077 0.000 -9.335
ENSG00000189091 E002 0.2340080 0.2372322379 0.505720754   16 70523813 70523815 3 + 0.143 0.000 -11.921
ENSG00000189091 E003 7.6690957 0.0333641075 0.557155463 0.79924781 16 70523816 70523892 77 + 0.903 0.969 0.249
ENSG00000189091 E004 9.2590494 0.0122208346 0.441484193 0.71696150 16 70523893 70523928 36 + 0.971 1.048 0.281
ENSG00000189091 E005 0.2438580 0.0163554717 0.720481607   16 70523929 70524055 127 + 0.077 0.117 0.663
ENSG00000189091 E006 0.6083631 0.0181899498 0.953327866 0.98854798 16 70524550 70524863 314 + 0.200 0.208 0.078
ENSG00000189091 E007 0.8354434 0.0305587567 0.166941395 0.43740258 16 70524864 70525017 154 + 0.336 0.117 -1.922
ENSG00000189091 E008 16.5324746 0.0150223199 0.811198656 0.93052452 16 70526587 70526726 140 + 1.229 1.246 0.060
ENSG00000189091 E009 0.0000000       16 70526901 70527014 114 +      
ENSG00000189091 E010 33.6686163 0.0024025494 0.260489579 0.55307465 16 70528873 70529199 327 + 1.556 1.494 -0.214
ENSG00000189091 E011 25.7377801 0.0052232807 0.906363982 0.97014835 16 70530745 70530917 173 + 1.416 1.424 0.027
ENSG00000189091 E012 21.8247410 0.0006765038 0.140594531 0.39890712 16 70532479 70532620 142 + 1.311 1.404 0.323
ENSG00000189091 E013 21.5467008 0.0009265548 0.403206167 0.68622661 16 70535308 70535420 113 + 1.323 1.376 0.186
ENSG00000189091 E014 19.1408051 0.0007538665 0.314155160 0.60725555 16 70538323 70538394 72 + 1.323 1.254 -0.242
ENSG00000189091 E015 18.5295642 0.0010969278 0.304374883 0.59777711 16 70538395 70538460 66 + 1.311 1.239 -0.253
ENSG00000189091 E016 23.0260249 0.0008341451 0.007083826 0.06357896 16 70539104 70539207 104 + 1.436 1.261 -0.606
ENSG00000189091 E017 16.8244409 0.0020676409 0.001523552 0.02073192 16 70541669 70541738 70 + 1.327 1.082 -0.867
ENSG00000189091 E018 17.6082336 0.0007532490 0.983663179 0.99869026 16 70541739 70541834 96 + 1.263 1.261 -0.005
ENSG00000189091 E019 15.2488837 0.0009491067 0.230633328 0.51906811 16 70544438 70544533 96 + 1.165 1.254 0.315
ENSG00000189091 E020 10.8139984 0.0012723574 0.905003265 0.96954500 16 70548370 70548442 73 + 1.061 1.071 0.037
ENSG00000189091 E021 0.8437879 0.0135173278 0.577768228 0.81131629 16 70548443 70548512 70 + 0.295 0.208 -0.659
ENSG00000189091 E022 1.8019279 0.0525429196 0.364489794 0.65318198 16 70550203 70550567 365 + 0.497 0.349 -0.796
ENSG00000189091 E023 0.5079160 0.2149466873 0.029867479 0.16258303 16 70550568 70550649 82 + 0.000 0.349 12.947
ENSG00000189091 E024 1.4871806 0.0125197744 0.054311483 0.23209219 16 70550650 70550678 29 + 0.250 0.540 1.663
ENSG00000189091 E025 1.1066483 0.0650078216 0.347947223 0.63847759 16 70554106 70554445 340 + 0.250 0.405 0.985
ENSG00000189091 E026 21.5832295 0.0022527939 0.666875413 0.86144329 16 70554446 70554597 152 + 1.358 1.329 -0.100
ENSG00000189091 E027 30.8676487 0.0004643242 0.727739714 0.89131928 16 70555051 70555206 156 + 1.488 1.507 0.064
ENSG00000189091 E028 39.5086286 0.0009022017 0.806031540 0.92815130 16 70556179 70556334 156 + 1.595 1.607 0.041
ENSG00000189091 E029 0.3810317 0.0314198534 0.042117627   16 70556335 70556597 263 + 0.000 0.284 13.207
ENSG00000189091 E030 33.1796401 0.0035248920 0.884813314 0.96117789 16 70556886 70557029 144 + 1.522 1.531 0.029
ENSG00000189091 E031 0.3542802 0.0260635151 0.229444652   16 70560350 70560468 119 + 0.200 0.000 -13.270
ENSG00000189091 E032 37.4212107 0.0076785395 0.987700658 0.99983114 16 70560469 70560591 123 + 1.577 1.576 -0.005
ENSG00000189091 E033 0.1170040 0.0116720130 0.881890214   16 70561349 70561629 281 + 0.077 0.000 -11.873
ENSG00000189091 E034 45.0547743 0.0003270583 0.948861778 0.98676200 16 70561630 70561784 155 + 1.657 1.654 -0.010
ENSG00000189091 E035 0.0000000       16 70563729 70563875 147 +      
ENSG00000189091 E036 45.7719099 0.0003233994 0.922997062 0.97632951 16 70563876 70564050 175 + 1.664 1.660 -0.015
ENSG00000189091 E037 44.5590137 0.0003999614 0.910167477 0.97153943 16 70565065 70565270 206 + 1.653 1.648 -0.018
ENSG00000189091 E038 39.4861801 0.0053717418 0.315938085 0.60880363 16 70565368 70565524 157 + 1.622 1.565 -0.193
ENSG00000189091 E039 0.3624961 0.0165860843 0.921337750   16 70565525 70565720 196 + 0.143 0.117 -0.337
ENSG00000189091 E040 46.2272928 0.0044037167 0.270699438 0.56437835 16 70567411 70567536 126 + 1.643 1.699 0.188
ENSG00000189091 E041 0.2537694 0.0160189857 0.121001965   16 70567537 70567541 5 + 0.000 0.208 12.770
ENSG00000189091 E042 75.0809247 0.0003107692 0.419875670 0.69931369 16 70568283 70568495 213 + 1.885 1.856 -0.095
ENSG00000189091 E043 36.7828959 0.0055178981 0.131618737 0.38488088 16 70569043 70569141 99 + 1.603 1.515 -0.301
ENSG00000189091 E044 0.6047813 0.2852816792 0.854753632 0.94876572 16 70569915 70570005 91 + 0.199 0.208 0.080
ENSG00000189091 E045 50.0168656 0.0003400888 0.803188768 0.92688412 16 70570006 70570149 144 + 1.704 1.693 -0.037
ENSG00000189091 E046 41.3357243 0.0075052101 0.357187876 0.64683111 16 70571095 70571199 105 + 1.639 1.586 -0.181
ENSG00000189091 E047 194.9713042 0.0002173671 0.001430725 0.01971001 16 70571673 70576300 4628 + 2.257 2.322 0.218
ENSG00000189091 E048 0.8596806 0.0152012278 0.330062009 0.62257329 16 70576301 70576348 48 + 0.200 0.349 1.078
ENSG00000189091 E049 9.3347742 0.0890705194 0.927213542 0.97834951 16 70576349 70577317 969 + 1.014 0.997 -0.062
ENSG00000189091 E050 2.7887511 0.0086224390 0.703574936 0.87942747 16 70577318 70577670 353 + 0.593 0.540 -0.244

Help

Please Click HERE to learn more details about the results from DEXseq.