ENSG00000196214

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000439461 ENSG00000196214 No_inf pgKDN_inf ZNF766 protein_coding protein_coding 10.88393 10.55803 12.86151 0.6253794 0.8993208 0.2844747 2.6648605 3.076941 2.6619702 0.1425017 0.1281976 -0.2082739 0.2502417 0.2964 0.208525 -0.087875 0.76899153 0.04029477 FALSE TRUE
ENST00000595000 ENSG00000196214 No_inf pgKDN_inf ZNF766 protein_coding protein_coding 10.88393 10.55803 12.86151 0.6253794 0.8993208 0.2844747 1.2917705 0.000000 2.5974801 0.0000000 0.9930429 8.0265124 0.1104250 0.0000 0.197475 0.197475 0.04029477 0.04029477 FALSE TRUE
ENST00000599581 ENSG00000196214 No_inf pgKDN_inf ZNF766 protein_coding protein_coding 10.88393 10.55803 12.86151 0.6253794 0.8993208 0.2844747 5.8595303 6.054662 6.9050006 0.3025644 0.6174878 0.1893022 0.5413083 0.5756 0.541625 -0.033975 0.91617279 0.04029477 FALSE TRUE
ENST00000600016 ENSG00000196214 No_inf pgKDN_inf ZNF766 protein_coding retained_intron 10.88393 10.55803 12.86151 0.6253794 0.8993208 0.2844747 0.6108738 1.113160 0.4099687 0.3820079 0.4099687 -1.4192090 0.0552250 0.0997 0.031900 -0.067800 0.50312561 0.04029477   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000196214 E001 0.2442663 0.0162650921 0.9623319373   19 52269587 52269592 6 + 0.098 0.093 -0.083
ENSG00000196214 E002 3.4113637 0.0087575515 0.3667077287 0.65537493 19 52269593 52269631 39 + 0.702 0.586 -0.498
ENSG00000196214 E003 0.1271363 0.0124458153 0.5732014715   19 52274462 52274474 13 + 0.000 0.093 10.258
ENSG00000196214 E004 0.1271363 0.0124458153 0.5732014715   19 52274475 52274513 39 + 0.000 0.093 10.258
ENSG00000196214 E005 0.2539903 0.0161625953 0.2646515222   19 52274514 52274582 69 + 0.000 0.169 11.188
ENSG00000196214 E006 0.2444846 0.0163320027 0.9618483047   19 52274583 52274669 87 + 0.098 0.093 -0.083
ENSG00000196214 E007 0.0000000       19 52275578 52275607 30 +      
ENSG00000196214 E008 0.1265070 0.0123463617 0.5733262850   19 52277154 52277541 388 + 0.000 0.093 10.258
ENSG00000196214 E009 7.3038143 0.0020089529 0.1229802954 0.37112910 19 52282111 52282237 127 + 0.992 0.842 -0.569
ENSG00000196214 E010 0.3713386 0.1653078041 0.6575975846   19 52282238 52282574 337 + 0.098 0.169 0.917
ENSG00000196214 E011 8.6351933 0.0062993411 0.0793432030 0.28887660 19 52283285 52283413 129 + 1.064 0.897 -0.618
ENSG00000196214 E012 0.7340550 0.4317256451 0.8500354576 0.94685583 19 52288042 52288115 74 + 0.244 0.234 -0.081
ENSG00000196214 E013 59.8567816 0.0003475269 0.0211678309 0.13157379 19 52290066 52291124 1059 + 1.821 1.748 -0.248
ENSG00000196214 E014 61.3364863 0.0002773408 0.6481174121 0.85142528 19 52291125 52292148 1024 + 1.785 1.801 0.055
ENSG00000196214 E015 51.9960706 0.0003088952 0.0005986788 0.01005266 19 52292149 52296046 3898 + 1.652 1.778 0.428

Help

Please Click HERE to learn more details about the results from DEXseq.