ENSG00000196290

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000359683 ENSG00000196290 No_inf pgKDN_inf NIF3L1 protein_coding protein_coding 18.28236 20.48239 16.89939 2.170533 1.412653 -0.2772635 2.380803 0.8548430 3.961068 0.8548430 3.0424422 2.1990168 0.1641667 0.055275 0.282925 0.22765 0.81353703 0.04766753 FALSE TRUE
ENST00000409020 ENSG00000196290 No_inf pgKDN_inf NIF3L1 protein_coding protein_coding 18.28236 20.48239 16.89939 2.170533 1.412653 -0.2772635 1.980323 1.3867719 2.253473 0.5671864 1.4423055 0.6964415 0.1029500 0.063450 0.124200 0.06075 1.00000000 0.04766753 FALSE TRUE
ENST00000454952 ENSG00000196290 No_inf pgKDN_inf NIF3L1 protein_coding protein_coding 18.28236 20.48239 16.89939 2.170533 1.412653 -0.2772635 3.871705 6.2669024 1.623284 1.6812913 0.7984814 -1.9422771 0.1967750 0.290975 0.088425 -0.20255 0.22720769 0.04766753 FALSE FALSE
MSTRG.17460.1 ENSG00000196290 No_inf pgKDN_inf NIF3L1 protein_coding   18.28236 20.48239 16.89939 2.170533 1.412653 -0.2772635 2.250105 0.2542123 4.999637 0.2542123 2.5096901 4.2449364 0.1243833 0.011425 0.284925 0.27350 0.18671027 0.04766753 FALSE TRUE
MSTRG.17460.11 ENSG00000196290 No_inf pgKDN_inf NIF3L1 protein_coding   18.28236 20.48239 16.89939 2.170533 1.412653 -0.2772635 4.278327 6.1446012 3.790685 2.7470279 2.1885670 -0.6954060 0.2047167 0.265975 0.203025 -0.06295 0.84096775 0.04766753 FALSE TRUE
MSTRG.17460.3 ENSG00000196290 No_inf pgKDN_inf NIF3L1 protein_coding   18.28236 20.48239 16.89939 2.170533 1.412653 -0.2772635 3.375171 5.4085298 0.000000 2.2856951 0.0000000 -9.0817577 0.1990167 0.305400 0.000000 -0.30540 0.04766753 0.04766753 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000196290 E001 0.0000000       2 200889327 200889352 26 +      
ENSG00000196290 E002 0.2543986 0.0160639610 0.302923305   2 200889353 200889368 16 + 0.000 0.164 11.697
ENSG00000196290 E003 0.2543986 0.0160639610 0.302923305   2 200889369 200889370 2 + 0.000 0.164 11.699
ENSG00000196290 E004 0.7535987 0.0153660145 0.136264775 0.39259105 2 200889371 200889387 17 + 0.101 0.332 2.132
ENSG00000196290 E005 0.8804527 0.0163774345 0.079001506 0.28822751 2 200889388 200889391 4 + 0.101 0.376 2.395
ENSG00000196290 E006 0.6161368 0.0160639408 0.791025475 0.91993774 2 200889392 200889414 23 + 0.183 0.227 0.395
ENSG00000196290 E007 1.1058952 0.0117009955 0.929384789 0.97924199 2 200889415 200889446 32 + 0.311 0.332 0.132
ENSG00000196290 E008 4.8675243 0.0155598290 0.089964540 0.31157436 2 200889447 200889652 206 + 0.862 0.669 -0.775
ENSG00000196290 E009 0.7427115 0.0142781084 0.532995780 0.78349944 2 200890523 200890585 63 + 0.183 0.283 0.810
ENSG00000196290 E010 3.1242531 0.1160317662 0.040460025 0.19510938 2 200891736 200891789 54 + 0.363 0.747 1.810
ENSG00000196290 E011 5.1206350 0.1192721843 0.024303890 0.14291387 2 200891790 200891916 127 + 0.525 0.921 1.640
ENSG00000196290 E012 1.8753582 0.0083033225 0.037148710 0.18560246 2 200891917 200891917 1 + 0.251 0.574 1.810
ENSG00000196290 E013 4.2518989 0.0046205051 0.002123581 0.02674759 2 200891918 200891968 51 + 0.452 0.857 1.757
ENSG00000196290 E014 25.7831835 0.0006446950 0.937081329 0.98208705 2 200891969 200892379 411 + 1.421 1.430 0.030
ENSG00000196290 E015 9.5657742 0.0165524316 0.809337340 0.92963602 2 200893246 200893408 163 + 1.028 1.017 -0.042
ENSG00000196290 E016 0.3810317 0.0189343297 0.138682129   2 200894833 200894983 151 + 0.000 0.227 12.283
ENSG00000196290 E017 14.0325310 0.0119670660 0.566743220 0.80472643 2 200895264 200895390 127 + 1.140 1.201 0.218
ENSG00000196290 E018 0.0000000       2 200897074 200897075 2 +      
ENSG00000196290 E019 17.8334928 0.0007703553 0.056211362 0.23640858 2 200897076 200897214 139 + 1.330 1.220 -0.388
ENSG00000196290 E020 16.8774333 0.0009491648 0.124311473 0.37361966 2 200899385 200899468 84 + 1.297 1.207 -0.316
ENSG00000196290 E021 22.6622852 0.0012465770 0.273042648 0.56684529 2 200903494 200903669 176 + 1.399 1.349 -0.175
ENSG00000196290 E022 17.1349693 0.0013071010 0.236549532 0.52552055 2 200903670 200903961 292 + 1.291 1.226 -0.231

Help

Please Click HERE to learn more details about the results from DEXseq.