ENSG00000196323

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000357899 ENSG00000196323 No_inf pgKDN_inf ZBTB44 protein_coding protein_coding 12.11528 11.39854 13.18729 0.6155409 1.343421 0.2101281 0.2554452 0.7663355 0.0000000 0.4834073 0.0000000 -6.2786083 0.02283333 0.068500 0.000000 -0.068500 4.895254e-01 1.817971e-06 TRUE TRUE
ENST00000397753 ENSG00000196323 No_inf pgKDN_inf ZBTB44 protein_coding protein_coding 12.11528 11.39854 13.18729 0.6155409 1.343421 0.2101281 0.3381092 1.0143275 0.0000000 0.7052232 0.0000000 -6.6785333 0.02800000 0.084000 0.000000 -0.084000 4.831729e-01 1.817971e-06 TRUE TRUE
ENST00000525623 ENSG00000196323 No_inf pgKDN_inf ZBTB44 protein_coding retained_intron 12.11528 11.39854 13.18729 0.6155409 1.343421 0.2101281 1.0111725 0.2022626 2.8312550 0.2022626 1.9424918 3.7426063 0.06558333 0.016575 0.180175 0.163600 7.470696e-01 1.817971e-06 FALSE FALSE
ENST00000525842 ENSG00000196323 No_inf pgKDN_inf ZBTB44 protein_coding protein_coding 12.11528 11.39854 13.18729 0.6155409 1.343421 0.2101281 2.3240495 1.8019690 3.0964650 1.0713238 0.3611031 0.7777155 0.19980833 0.160025 0.246675 0.086650 7.431201e-01 1.817971e-06 FALSE TRUE
ENST00000527478 ENSG00000196323 No_inf pgKDN_inf ZBTB44 protein_coding protein_coding 12.11528 11.39854 13.18729 0.6155409 1.343421 0.2101281 0.5482424 0.0000000 0.6204445 0.0000000 0.6204445 5.9782974 0.04992500 0.000000 0.060800 0.060800 8.589759e-01 1.817971e-06 FALSE TRUE
ENST00000528448 ENSG00000196323 No_inf pgKDN_inf ZBTB44 protein_coding protein_coding 12.11528 11.39854 13.18729 0.6155409 1.343421 0.2101281 1.4479785 0.0000000 1.1840251 0.0000000 1.1840251 6.8996893 0.09510000 0.000000 0.085225 0.085225 8.500623e-01 1.817971e-06 FALSE FALSE
ENST00000530205 ENSG00000196323 No_inf pgKDN_inf ZBTB44 protein_coding protein_coding 12.11528 11.39854 13.18729 0.6155409 1.343421 0.2101281 0.5367074 0.0000000 0.7447258 0.0000000 0.4304359 6.2378806 0.04021667 0.000000 0.052975 0.052975 4.880187e-01 1.817971e-06 FALSE TRUE
MSTRG.5775.10 ENSG00000196323 No_inf pgKDN_inf ZBTB44 protein_coding   12.11528 11.39854 13.18729 0.6155409 1.343421 0.2101281 1.0342419 0.0000000 1.3173795 0.0000000 0.8126657 7.0524371 0.08485000 0.000000 0.116175 0.116175 5.358752e-01 1.817971e-06 TRUE TRUE
MSTRG.5775.6 ENSG00000196323 No_inf pgKDN_inf ZBTB44 protein_coding   12.11528 11.39854 13.18729 0.6155409 1.343421 0.2101281 2.1146506 3.4673053 2.2729337 1.3028965 0.8136141 -0.6070808 0.18034167 0.307600 0.160625 -0.146975 8.428872e-01 1.817971e-06 FALSE TRUE
MSTRG.5775.7 ENSG00000196323 No_inf pgKDN_inf ZBTB44 protein_coding   12.11528 11.39854 13.18729 0.6155409 1.343421 0.2101281 1.6764666 3.6631534 0.0000000 0.7706051 0.0000000 -8.5208754 0.15605000 0.322550 0.000000 -0.322550 1.817971e-06 1.817971e-06 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000196323 E001 0.0000000       11 130226677 130226677 1 -      
ENSG00000196323 E002 0.0000000       11 130226678 130226683 6 -      
ENSG00000196323 E003 0.0000000       11 130226684 130226684 1 -      
ENSG00000196323 E004 0.2537694 0.0160824090 4.517400e-01   11 130226685 130226707 23 - 0.000 0.142 10.133
ENSG00000196323 E005 93.5026845 0.0002934653 1.680779e-06 7.310577e-05 11 130226708 130228356 1649 - 1.862 2.008 0.493
ENSG00000196323 E006 69.9364542 0.0024143425 7.224427e-03 6.443257e-02 11 130228357 130229828 1472 - 1.765 1.872 0.360
ENSG00000196323 E007 8.0758643 0.0043728703 1.297819e-01 3.821152e-01 11 130229829 130229974 146 - 0.837 0.996 0.601
ENSG00000196323 E008 28.0700567 0.0005639043 7.715487e-03 6.745454e-02 11 130229975 130230978 1004 - 1.343 1.500 0.542
ENSG00000196323 E009 33.3865569 0.0083699037 6.461719e-01 8.502474e-01 11 130230979 130231638 660 - 1.500 1.533 0.114
ENSG00000196323 E010 7.0055421 0.0056822622 2.795651e-01 5.728149e-01 11 130231639 130231665 27 - 0.956 0.845 -0.421
ENSG00000196323 E011 7.6479987 0.0058868410 7.657122e-01 9.089251e-01 11 130231666 130231715 50 - 0.941 0.912 -0.109
ENSG00000196323 E012 60.9149965 0.0002717205 3.627824e-01 6.519203e-01 11 130231716 130233307 1592 - 1.796 1.765 -0.107
ENSG00000196323 E013 0.6268712 0.0154177241 3.907633e-01 6.761266e-01 11 130233308 130233334 27 - 0.117 0.249 1.325
ENSG00000196323 E014 0.6251720 0.0154304399 3.907960e-01 6.761266e-01 11 130233335 130233382 48 - 0.117 0.249 1.326
ENSG00000196323 E015 10.6605475 0.0080514628 3.136951e-02 1.671161e-01 11 130233383 130234155 773 - 1.165 0.970 -0.708
ENSG00000196323 E016 2.3309763 0.0073300143 4.353788e-01 7.122315e-01 11 130234156 130234273 118 - 0.578 0.468 -0.523
ENSG00000196323 E017 0.7171887 0.0140504060 2.543734e-02 1.469828e-01 11 130236110 130236216 107 - 0.406 0.077 -2.996
ENSG00000196323 E018 0.3634051 0.0167901157 3.320590e-01   11 130236631 130236792 162 - 0.209 0.077 -1.675
ENSG00000196323 E019 7.9582630 0.0051335961 5.046401e-02 2.220005e-01 11 130236793 130237009 217 - 1.049 0.857 -0.719
ENSG00000196323 E020 6.6228746 0.0022459144 1.480789e-01 4.097107e-01 11 130237010 130237093 84 - 0.956 0.808 -0.568
ENSG00000196323 E021 10.6982360 0.0255771798 3.756851e-01 6.630972e-01 11 130238444 130238553 110 - 1.106 1.021 -0.308
ENSG00000196323 E022 3.8111066 0.2073507855 6.131704e-01 8.318104e-01 11 130238554 130238556 3 - 0.727 0.633 -0.397
ENSG00000196323 E023 5.4018855 0.0669857386 4.259630e-01 7.048154e-01 11 130238557 130238607 51 - 0.856 0.752 -0.412
ENSG00000196323 E024 1.1420295 0.1625365943 2.167853e-02 1.335477e-01 11 130238815 130239811 997 - 0.000 0.438 13.814
ENSG00000196323 E025 7.6251895 0.0019421212 4.105045e-01 6.923340e-01 11 130239812 130239896 85 - 0.971 0.891 -0.300
ENSG00000196323 E026 13.8550116 0.0055034918 3.543977e-02 1.802195e-01 11 130260856 130261029 174 - 1.255 1.088 -0.598
ENSG00000196323 E027 17.4659569 0.0014336565 1.953729e-04 4.101690e-03 11 130261030 130261255 226 - 1.395 1.139 -0.897
ENSG00000196323 E028 30.4183734 0.0005757031 1.119802e-03 1.636288e-02 11 130261256 130261929 674 - 1.581 1.412 -0.581
ENSG00000196323 E029 0.0000000       11 130261930 130261931 2 -      
ENSG00000196323 E030 6.5825145 0.0023265896 1.146814e-02 8.802085e-02 11 130314375 130314917 543 - 1.012 0.752 -0.996

Help

Please Click HERE to learn more details about the results from DEXseq.