ENSG00000196365

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000360614 ENSG00000196365 No_inf pgKDN_inf LONP1 protein_coding protein_coding 36.1728 26.62359 39.08966 2.301778 2.601252 0.553909 10.3135890 5.698692 9.549733 2.5137857 3.000827 0.7438101 0.27768333 0.217725 0.24920 0.031475 0.91011832 0.01003393 FALSE TRUE
ENST00000585374 ENSG00000196365 No_inf pgKDN_inf LONP1 protein_coding protein_coding 36.1728 26.62359 39.08966 2.301778 2.601252 0.553909 10.7645557 2.516846 17.621304 2.5168461 2.599611 2.8027295 0.27445833 0.081875 0.45310 0.371225 0.01003393 0.01003393 FALSE TRUE
ENST00000589473 ENSG00000196365 No_inf pgKDN_inf LONP1 protein_coding protein_coding 36.1728 26.62359 39.08966 2.301778 2.601252 0.553909 2.5209093 2.544896 3.396927 2.5448960 3.396927 0.4152067 0.06564167 0.082775 0.07610 -0.006675 1.00000000 0.01003393 FALSE FALSE
ENST00000590558 ENSG00000196365 No_inf pgKDN_inf LONP1 protein_coding nonsense_mediated_decay 36.1728 26.62359 39.08966 2.301778 2.601252 0.553909 0.6978006 1.827416 0.000000 0.6170504 0.000000 -7.5215347 0.02643333 0.073450 0.00000 -0.073450 0.03058068 0.01003393 FALSE TRUE
ENST00000593119 ENSG00000196365 No_inf pgKDN_inf LONP1 protein_coding protein_coding 36.1728 26.62359 39.08966 2.301778 2.601252 0.553909 0.7382683 2.214805 0.000000 2.2148049 0.000000 -7.7975350 0.03470000 0.104100 0.00000 -0.104100 0.83804119 0.01003393 FALSE TRUE
MSTRG.14367.8 ENSG00000196365 No_inf pgKDN_inf LONP1 protein_coding   36.1728 26.62359 39.08966 2.301778 2.601252 0.553909 6.6574775 7.462958 4.646337 1.8473070 1.831435 -0.6824840 0.19412500 0.279875 0.12245 -0.157425 0.56755593 0.01003393 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000196365 E001 0.0000000       19 5691834 5691834 1 -      
ENSG00000196365 E002 6.3295532 0.0076222079 7.657119e-01 0.9089250813 19 5691835 5691954 120 - 0.845 0.880 0.133
ENSG00000196365 E003 8.5016264 0.0143644280 7.879945e-01 0.9186938689 19 5691955 5691992 38 - 0.983 0.958 -0.091
ENSG00000196365 E004 32.8890497 0.0004417070 9.440111e-06 0.0003245524 19 5691993 5692208 216 - 1.415 1.642 0.775
ENSG00000196365 E005 0.0000000       19 5692209 5692242 34 -      
ENSG00000196365 E006 34.9074376 0.0037121956 1.053233e-03 0.0155833446 19 5693298 5693462 165 - 1.466 1.645 0.611
ENSG00000196365 E007 51.5654941 0.0128712404 8.481127e-01 0.9462614188 19 5693552 5693769 218 - 1.709 1.723 0.045
ENSG00000196365 E008 35.0174973 0.0004399529 7.166075e-02 0.2713145556 19 5694387 5694552 166 - 1.511 1.601 0.309
ENSG00000196365 E009 25.4895968 0.0005592894 1.974879e-01 0.4787538039 19 5694761 5694901 141 - 1.384 1.460 0.262
ENSG00000196365 E010 26.9257944 0.0098264785 4.737777e-01 0.7407231955 19 5696054 5696170 117 - 1.460 1.412 -0.163
ENSG00000196365 E011 32.2990050 0.0004428066 2.781398e-02 0.1557432661 19 5696249 5696371 123 - 1.561 1.446 -0.395
ENSG00000196365 E012 1.7410735 0.0078891157 1.926820e-02 0.1240552683 19 5696372 5696669 298 - 0.255 0.601 1.903
ENSG00000196365 E013 14.8138227 0.0027521237 5.888592e-01 0.8177016575 19 5696670 5696686 17 - 1.210 1.169 -0.144
ENSG00000196365 E014 22.6456900 0.0085077713 7.914589e-01 0.9201471079 19 5696687 5696757 71 - 1.358 1.381 0.079
ENSG00000196365 E015 32.1609505 0.0004242242 4.143498e-01 0.6946193155 19 5699027 5699205 179 - 1.532 1.490 -0.142
ENSG00000196365 E016 22.9053871 0.0191733153 5.254891e-01 0.7782126729 19 5700789 5700884 96 - 1.351 1.402 0.179
ENSG00000196365 E017 13.0862582 0.0011020386 7.761408e-02 0.2850315502 19 5700885 5700908 24 - 1.079 1.219 0.500
ENSG00000196365 E018 10.6265761 0.0013905668 1.896564e-01 0.4684861903 19 5700909 5700927 19 - 1.009 1.123 0.415
ENSG00000196365 E019 0.9913483 0.0151695659 2.103300e-01 0.4947841050 19 5704109 5704237 129 - 0.204 0.397 1.318
ENSG00000196365 E020 23.6774944 0.0006283609 6.283537e-01 0.8403707131 19 5705772 5705910 139 - 1.398 1.370 -0.097
ENSG00000196365 E021 12.1702933 0.0011648519 9.309218e-03 0.0767594190 19 5705911 5705947 37 - 1.193 0.972 -0.802
ENSG00000196365 E022 13.3275821 0.0011206716 3.124611e-01 0.6058356006 19 5705948 5705992 45 - 1.182 1.103 -0.284
ENSG00000196365 E023 15.2080355 0.0016748106 8.860482e-01 0.9618994013 19 5707060 5707143 84 - 1.199 1.211 0.044
ENSG00000196365 E024 14.7196505 0.0010041091 7.930522e-01 0.9210504017 19 5707697 5707811 115 - 1.182 1.203 0.075
ENSG00000196365 E025 7.9882972 0.0130888147 4.227716e-01 0.7020463629 19 5707812 5707826 15 - 0.982 0.897 -0.322
ENSG00000196365 E026 2.0967058 0.0321900879 1.453666e-01 0.4057446782 19 5707827 5708032 206 - 0.380 0.601 1.095
ENSG00000196365 E027 13.6775227 0.0015261707 2.220877e-01 0.5093587090 19 5708342 5708403 62 - 1.199 1.103 -0.343
ENSG00000196365 E028 3.8218656 0.0056310047 4.881035e-02 0.2176799273 19 5708404 5708958 555 - 0.557 0.805 1.050
ENSG00000196365 E029 12.9386254 0.0228891567 2.014765e-01 0.4838901940 19 5711771 5711818 48 - 1.188 1.060 -0.460
ENSG00000196365 E030 22.5049253 0.0013881626 5.813465e-02 0.2413357810 19 5711819 5711950 132 - 1.412 1.291 -0.419
ENSG00000196365 E031 11.4791982 0.0011780590 8.467621e-02 0.3006337034 19 5711951 5712002 52 - 1.146 0.999 -0.535
ENSG00000196365 E032 0.1265070 0.0123761055 3.562800e-01   19 5712003 5712070 68 - 0.000 0.114 10.516
ENSG00000196365 E033 0.1268540 0.0123068528 3.564206e-01   19 5712463 5712468 6 - 0.000 0.114 10.516
ENSG00000196365 E034 17.9475707 0.0009153896 2.346967e-03 0.0287659008 19 5713134 5713253 120 - 1.351 1.133 -0.768
ENSG00000196365 E035 12.1485191 0.0011610672 2.460455e-03 0.0297538474 19 5714183 5714271 89 - 1.204 0.944 -0.948
ENSG00000196365 E036 0.0000000       19 5714903 5715040 138 -      
ENSG00000196365 E037 1.0880881 0.0181960011 6.809036e-01 0.8681671485 19 5717355 5717616 262 - 0.343 0.278 -0.419
ENSG00000196365 E038 10.0537050 0.0087261465 4.846902e-01 0.7487639142 19 5719704 5719816 113 - 1.065 0.999 -0.240
ENSG00000196365 E039 3.7531007 0.0462855690 6.241077e-01 0.8382672891 19 5719817 5719833 17 - 0.699 0.633 -0.281
ENSG00000196365 E040 5.4825756 0.0708288199 7.778372e-01 0.9148012809 19 5719834 5719932 99 - 0.793 0.825 0.128
ENSG00000196365 E041 3.0385265 0.0050728954 9.872753e-01 0.9996377914 19 5719933 5720008 76 - 0.602 0.601 -0.004
ENSG00000196365 E042 2.5488019 0.0156465027 8.539725e-01 0.9484206272 19 5720009 5720042 34 - 0.557 0.531 -0.120
ENSG00000196365 E043 2.8967837 0.0076054126 2.709052e-01 0.5646109793 19 5720043 5720165 123 - 0.644 0.491 -0.699
ENSG00000196365 E044 0.2363338 0.0157471144 4.122432e-01   19 5720219 5720572 354 - 0.146 0.000 -10.460

Help

Please Click HERE to learn more details about the results from DEXseq.