ENSG00000196369

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000619678 ENSG00000196369 No_inf pgKDN_inf SRGAP2B protein_coding nonsense_mediated_decay 25.63463 39.17647 22.41682 6.335587 2.723539 -0.8051307 1.018432 0.000000 1.9886263 0.0000000 0.6950667 7.6428649 0.05623333 0.000000 0.081650 0.081650 0.00873224 0.00873224 FALSE TRUE
ENST00000621582 ENSG00000196369 No_inf pgKDN_inf SRGAP2B protein_coding nonsense_mediated_decay 25.63463 39.17647 22.41682 6.335587 2.723539 -0.8051307 10.365541 15.505862 9.5786299 5.7042448 2.0585128 -0.6943472 0.36192500 0.343400 0.413000 0.069600 0.86238863 0.00873224   FALSE
ENST00000641863 ENSG00000196369 No_inf pgKDN_inf SRGAP2B protein_coding protein_coding 25.63463 39.17647 22.41682 6.335587 2.723539 -0.8051307 4.109929 3.364213 7.2218312 1.2148741 0.5071376 1.0998098 0.19131667 0.094350 0.334950 0.240600 0.20721521 0.00873224 FALSE TRUE
MSTRG.1697.1 ENSG00000196369 No_inf pgKDN_inf SRGAP2B protein_coding   25.63463 39.17647 22.41682 6.335587 2.723539 -0.8051307 5.206859 10.398050 2.0545825 0.5872050 0.1560889 -2.3337778 0.20848333 0.287575 0.095375 -0.192200 0.04366354 0.00873224 FALSE TRUE
MSTRG.1697.3 ENSG00000196369 No_inf pgKDN_inf SRGAP2B protein_coding   25.63463 39.17647 22.41682 6.335587 2.723539 -0.8051307 1.472626 4.272318 0.1455612 0.6184105 0.1455612 -4.7828376 0.04409167 0.122550 0.009725 -0.112825 0.03087201 0.00873224 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000196369 E001 0.0000000       1 144885107 144885746 640 -      
ENSG00000196369 E002 0.7416416 0.0211583447 0.968029122 0.99359956 1 144885747 144887102 1356 - 0.231 0.226 -0.046
ENSG00000196369 E003 0.3810317 0.0235268365 0.349544844   1 144887103 144887264 162 - 0.000 0.179 10.752
ENSG00000196369 E004 0.3810317 0.0235268365 0.349544844   1 144887265 144887287 23 - 0.000 0.179 10.752
ENSG00000196369 E005 19.1190876 0.0011652586 0.001357317 0.01895736 1 144887288 144889280 1993 - 1.113 1.328 0.761
ENSG00000196369 E006 6.6679271 0.0274615499 0.331847169 0.62400269 1 144889281 144892381 3101 - 0.924 0.821 -0.394
ENSG00000196369 E007 0.0000000       1 144893408 144893509 102 -      
ENSG00000196369 E008 0.0000000       1 144897116 144897235 120 -      
ENSG00000196369 E009 0.0000000       1 144897236 144897337 102 -      
ENSG00000196369 E010 0.0000000       1 144897338 144897340 3 -      
ENSG00000196369 E011 15.2940018 0.0009480749 0.036271949 0.18298487 1 144905091 144905219 129 - 1.269 1.134 -0.480
ENSG00000196369 E012 14.9130961 0.0009814478 0.020461600 0.12874194 1 144905859 144906039 181 - 1.269 1.117 -0.540
ENSG00000196369 E013 0.0000000       1 144906040 144906074 35 -      
ENSG00000196369 E014 0.0000000       1 144914692 144914754 63 -      
ENSG00000196369 E015 0.0000000       1 144930270 144930313 44 -      
ENSG00000196369 E016 2.1322076 0.0375980016 0.195303511 0.47556337 1 144955439 144955601 163 - 0.313 0.530 1.176
ENSG00000196369 E017 0.1272623 0.0126294835 1.000000000   1 144957548 144957673 126 - 0.000 0.068 9.362
ENSG00000196369 E018 3.6269483 0.0042912447 0.155043289 0.42073212 1 144960338 144960398 61 - 0.493 0.692 0.893
ENSG00000196369 E019 3.3548304 0.0137233134 0.753038789 0.90279517 1 144995008 144995200 193 - 0.581 0.627 0.202
ENSG00000196369 E020 0.0000000       1 145092835 145092986 152 -      
ENSG00000196369 E021 0.0000000       1 145092987 145093042 56 -      
ENSG00000196369 E022 0.0000000       1 145093043 145093052 10 -      
ENSG00000196369 E023 0.0000000       1 145093053 145093443 391 -      
ENSG00000196369 E024 0.0000000       1 145094873 145094894 22 -      
ENSG00000196369 E025 0.5000168 0.0190012366 0.803118459 0.92686947 1 145094895 145095222 328 - 0.131 0.179 0.539
ENSG00000196369 E026 0.1186381 0.0120220775 0.239511045   1 145095223 145095390 168 - 0.131 0.000 -11.719
ENSG00000196369 E027 0.0000000       1 145095391 145095528 138 -      

Help

Please Click HERE to learn more details about the results from DEXseq.