ENSG00000196405

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000392920 ENSG00000196405 No_inf pgKDN_inf EVL protein_coding protein_coding 157.5543 222.4971 115.7805 6.908209 6.556298 -0.9423351 79.524124 90.59020 68.987205 1.1241885 2.1640923 -0.3929764 0.53244167 0.407975 0.599375 0.19140 0.0001306264 0.0001306264 FALSE TRUE
ENST00000402714 ENSG00000196405 No_inf pgKDN_inf EVL protein_coding protein_coding 157.5543 222.4971 115.7805 6.908209 6.556298 -0.9423351 8.194335 13.19460 5.354037 0.9485170 0.9018890 -1.2996491 0.05062500 0.059700 0.047500 -0.01220 0.8324446378 0.0001306264 FALSE TRUE
ENST00000555848 ENSG00000196405 No_inf pgKDN_inf EVL protein_coding retained_intron 157.5543 222.4971 115.7805 6.908209 6.556298 -0.9423351 14.808160 30.83259 8.098088 0.5726723 0.6805563 -1.9274904 0.08346667 0.138775 0.071225 -0.06755 0.0502568237 0.0001306264   FALSE
MSTRG.9050.17 ENSG00000196405 No_inf pgKDN_inf EVL protein_coding   157.5543 222.4971 115.7805 6.908209 6.556298 -0.9423351 20.498191 36.25727 8.698749 1.3310301 0.2865703 -2.0581309 0.12095000 0.163900 0.075550 -0.08835 0.0034319969 0.0001306264 TRUE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000196405 E001 23.9036202 5.221514e-03 4.870285e-01 7.506900e-01 14 99971449 99972057 609 + 1.320 1.370 0.174
ENSG00000196405 E002 0.0000000       14 100019382 100019575 194 +      
ENSG00000196405 E003 0.0000000       14 100019576 100019687 112 +      
ENSG00000196405 E004 3.6784958 2.244750e-02 8.855471e-02 3.086382e-01 14 100065417 100065420 4 + 0.789 0.557 -0.987
ENSG00000196405 E005 3.6879988 7.089232e-03 1.535600e-01 4.182670e-01 14 100065421 100065421 1 + 0.763 0.576 -0.793
ENSG00000196405 E006 4.0682752 5.891479e-03 2.974660e-01 5.905800e-01 14 100065422 100065424 3 + 0.763 0.629 -0.558
ENSG00000196405 E007 7.1435877 1.035433e-02 1.029781e-01 3.354079e-01 14 100065425 100065429 5 + 0.993 0.815 -0.677
ENSG00000196405 E008 7.5074359 7.041550e-03 5.885989e-02 2.433026e-01 14 100065430 100065431 2 + 1.024 0.826 -0.751
ENSG00000196405 E009 10.9399229 1.047538e-02 1.697872e-02 1.137694e-01 14 100065432 100065444 13 + 1.187 0.960 -0.821
ENSG00000196405 E010 27.6521750 5.833866e-04 1.466867e-02 1.034711e-01 14 100065445 100065511 67 + 1.514 1.370 -0.498
ENSG00000196405 E011 0.5999024 1.509324e-02 2.453134e-02 1.437879e-01 14 100066437 100066487 51 + 0.393 0.065 -3.180
ENSG00000196405 E012 0.0000000       14 100074503 100074615 113 +      
ENSG00000196405 E013 76.7330061 3.481804e-03 3.606129e-03 3.957130e-02 14 100084687 100084830 144 + 1.935 1.809 -0.424
ENSG00000196405 E014 42.4104359 3.330640e-04 1.361872e-04 3.059193e-03 14 100084831 100084855 25 + 1.718 1.536 -0.619
ENSG00000196405 E015 0.9849963 2.069714e-01 7.993645e-01 9.247137e-01 14 100084856 100085098 243 + 0.323 0.258 -0.442
ENSG00000196405 E016 0.0000000       14 100096947 100097045 99 +      
ENSG00000196405 E017 129.1941205 1.569362e-04 2.093551e-05 6.400995e-04 14 100097481 100097658 178 + 2.154 2.035 -0.396
ENSG00000196405 E018 0.9769393 6.101660e-01 6.846656e-01 8.695604e-01 14 100097659 100097745 87 + 0.393 0.218 -1.174
ENSG00000196405 E019 3.1217919 2.528411e-02 4.891360e-01 7.521300e-01 14 100102304 100102379 76 + 0.507 0.612 0.483
ENSG00000196405 E020 0.8640214 1.574277e-02 5.028823e-01 7.624879e-01 14 100102380 100102425 46 + 0.323 0.218 -0.765
ENSG00000196405 E021 10.1919244 3.302958e-03 2.526594e-03 3.036512e-02 14 100106024 100106825 802 + 1.187 0.911 -1.006
ENSG00000196405 E022 16.6793296 9.525014e-04 8.136930e-02 2.931970e-01 14 100106826 100108106 1281 + 1.296 1.166 -0.460
ENSG00000196405 E023 0.0000000       14 100114530 100114591 62 +      
ENSG00000196405 E024 67.3017498 4.969369e-04 8.284376e-03 7.078695e-02 14 100123539 100123602 64 + 1.865 1.760 -0.352
ENSG00000196405 E025 58.7540747 3.524236e-04 1.046640e-04 2.463815e-03 14 100126707 100126771 65 + 1.842 1.683 -0.539
ENSG00000196405 E026 38.3317194 3.527900e-04 9.639212e-05 2.302397e-03 14 100128519 100128586 68 + 1.683 1.488 -0.664
ENSG00000196405 E027 20.1303183 6.647898e-04 9.088250e-01 9.711026e-01 14 100128587 100128620 34 + 1.280 1.287 0.026
ENSG00000196405 E028 62.2450741 6.897999e-04 2.558977e-01 5.479863e-01 14 100128621 100128748 128 + 1.793 1.745 -0.163
ENSG00000196405 E029 96.7371713 1.847278e-04 9.119491e-06 3.153054e-04 14 100129563 100129684 122 + 2.044 1.902 -0.477
ENSG00000196405 E030 93.6072176 1.879623e-03 1.128993e-03 1.645706e-02 14 100132719 100132779 61 + 2.016 1.896 -0.403
ENSG00000196405 E031 1.3709945 1.119649e-02 8.081414e-01 9.291769e-01 14 100134653 100134867 215 + 0.323 0.362 0.235
ENSG00000196405 E032 2.5213925 1.650223e-02 3.132990e-02 1.670701e-01 14 100135008 100135522 515 + 0.240 0.594 1.990
ENSG00000196405 E033 1.2182375 1.227172e-02 5.961653e-02 2.448491e-01 14 100135771 100135904 134 + 0.507 0.218 -1.765
ENSG00000196405 E034 85.5149671 2.103941e-04 4.083510e-03 4.304926e-02 14 100135905 100135968 64 + 1.964 1.865 -0.334
ENSG00000196405 E035 3.2424797 6.563210e-02 4.675308e-01 7.358371e-01 14 100137106 100137577 472 + 0.507 0.629 0.557
ENSG00000196405 E036 89.2614080 1.758819e-04 1.938862e-04 4.080007e-03 14 100137578 100137644 67 + 1.999 1.874 -0.419
ENSG00000196405 E037 97.1988723 1.719734e-04 1.690987e-04 3.652451e-03 14 100137740 100137802 63 + 2.033 1.912 -0.406
ENSG00000196405 E038 105.6505840 1.475290e-04 1.027096e-27 5.109974e-25 14 100137803 100138567 765 + 1.666 2.071 1.366
ENSG00000196405 E039 37.6812414 4.037897e-04 3.753498e-10 3.472404e-08 14 100138568 100138811 244 + 1.245 1.628 1.323
ENSG00000196405 E040 23.6281238 5.830001e-04 2.323797e-07 1.242137e-05 14 100138812 100138897 86 + 1.039 1.434 1.396
ENSG00000196405 E041 59.5718386 2.598664e-04 2.358749e-07 1.257083e-05 14 100138898 100139333 436 + 1.561 1.798 0.805
ENSG00000196405 E042 17.5791013 1.404425e-03 5.759725e-05 1.496373e-03 14 100139334 100139369 36 + 0.959 1.305 1.243
ENSG00000196405 E043 139.7465333 1.393130e-04 7.755851e-23 2.698736e-20 14 100139370 100140292 923 + 1.873 2.176 1.014
ENSG00000196405 E044 198.1711590 1.020197e-04 2.723631e-33 1.859447e-30 14 100140293 100141179 887 + 2.019 2.327 1.030
ENSG00000196405 E045 126.0941832 1.368054e-04 8.434463e-02 2.999501e-01 14 100141180 100141246 67 + 2.097 2.048 -0.167
ENSG00000196405 E046 137.1193203 5.408319e-04 8.998061e-02 3.115939e-01 14 100141736 100141793 58 + 2.133 2.084 -0.164
ENSG00000196405 E047 10.1817378 1.507664e-03 9.723284e-01 9.947660e-01 14 100141794 100142235 442 + 1.009 1.012 0.009
ENSG00000196405 E048 229.0411421 8.534168e-05 1.918639e-01 4.716063e-01 14 100143701 100143890 190 + 2.340 2.312 -0.093
ENSG00000196405 E049 55.8278136 2.506361e-04 4.916214e-01 7.539127e-01 14 100143891 100144013 123 + 1.693 1.722 0.100
ENSG00000196405 E050 0.0000000       14 100144014 100144236 223 +      

Help

Please Click HERE to learn more details about the results from DEXseq.