ENSG00000196586

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000369975 ENSG00000196586 No_inf pgKDN_inf MYO6 protein_coding protein_coding 37.21834 51.04322 34.96107 3.503637 3.096772 -0.5458398 6.502196 11.753466 4.4026644 1.2858811 0.8748987 -1.4145912 0.16614167 0.228250 0.135475 -0.092775 4.739135e-01 2.202911e-09 FALSE TRUE
ENST00000430435 ENSG00000196586 No_inf pgKDN_inf MYO6 protein_coding protein_coding 37.21834 51.04322 34.96107 3.503637 3.096772 -0.5458398 18.219667 23.393923 17.1319258 3.8114176 2.2710722 -0.4492212 0.49438333 0.448525 0.483450 0.034925 8.760021e-01 2.202911e-09 FALSE FALSE
ENST00000627432 ENSG00000196586 No_inf pgKDN_inf MYO6 protein_coding protein_coding 37.21834 51.04322 34.96107 3.503637 3.096772 -0.5458398 2.174499 0.000000 4.2767756 0.0000000 0.6297657 8.7437491 0.06820833 0.000000 0.120775 0.120775 2.202911e-09 2.202911e-09 FALSE TRUE
ENST00000672093 ENSG00000196586 No_inf pgKDN_inf MYO6 protein_coding protein_coding 37.21834 51.04322 34.96107 3.503637 3.096772 -0.5458398 5.049159 7.617272 5.0417216 0.3101267 2.2146410 -0.5943920 0.12733333 0.152350 0.130450 -0.021900 8.437912e-01 2.202911e-09 FALSE TRUE
ENST00000672162 ENSG00000196586 No_inf pgKDN_inf MYO6 protein_coding retained_intron 37.21834 51.04322 34.96107 3.503637 3.096772 -0.5458398 1.806492 3.697037 0.8011285 0.2523528 0.1113658 -2.1922640 0.04430833 0.074400 0.023000 -0.051400 1.767586e-01 2.202911e-09 FALSE TRUE
MSTRG.24940.5 ENSG00000196586 No_inf pgKDN_inf MYO6 protein_coding   37.21834 51.04322 34.96107 3.503637 3.096772 -0.5458398 2.468614 2.380468 2.7594747 1.2001834 1.3293328 0.2123191 0.07395000 0.045025 0.090300 0.045275 8.826398e-01 2.202911e-09 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000196586 E001 0.0000000       6 75749201 75749201 1 +      
ENSG00000196586 E002 0.0000000       6 75749202 75749204 3 +      
ENSG00000196586 E003 0.1268540 0.0123277228 1.000000e+00   6 75749205 75749215 11 + 0.000 0.070 8.736
ENSG00000196586 E004 0.4902590 0.0158324184 5.105055e-01   6 75749216 75749234 19 + 0.226 0.131 -0.956
ENSG00000196586 E005 0.4902590 0.0158324184 5.105055e-01   6 75749235 75749235 1 + 0.226 0.131 -0.956
ENSG00000196586 E006 0.4902590 0.0158324184 5.105055e-01   6 75749236 75749238 3 + 0.226 0.131 -0.956
ENSG00000196586 E007 0.4902590 0.0158324184 5.105055e-01   6 75749239 75749245 7 + 0.226 0.131 -0.956
ENSG00000196586 E008 0.8705354 0.0124572850 7.629136e-01 9.074708e-01 6 75749246 75749249 4 + 0.226 0.274 0.366
ENSG00000196586 E009 1.1051700 0.0109928568 5.191585e-01 7.739164e-01 6 75749250 75749261 12 + 0.374 0.274 -0.634
ENSG00000196586 E010 2.7178477 0.0236879142 8.149096e-01 9.323955e-01 6 75749262 75749314 53 + 0.571 0.539 -0.148
ENSG00000196586 E011 6.3863929 0.0313949208 1.845559e-01 4.617146e-01 6 75749315 75749423 109 + 0.946 0.785 -0.621
ENSG00000196586 E012 0.1268540 0.0123277228 1.000000e+00   6 75757999 75758120 122 + 0.000 0.070 11.042
ENSG00000196586 E013 0.2363338 0.0156853787 8.567655e-02   6 75777453 75777570 118 + 0.226 0.000 -14.071
ENSG00000196586 E014 0.1268540 0.0123277228 1.000000e+00   6 75813599 75813688 90 + 0.000 0.070 11.042
ENSG00000196586 E015 3.6687650 0.0060724515 7.727352e-02 2.844050e-01 6 75817501 75817515 15 + 0.786 0.561 -0.956
ENSG00000196586 E016 4.1789792 0.0036409104 2.267169e-01 5.149176e-01 6 75817516 75817523 8 + 0.786 0.637 -0.615
ENSG00000196586 E017 4.4392038 0.0074257942 5.521101e-01 7.957277e-01 6 75817524 75817547 24 + 0.761 0.687 -0.304
ENSG00000196586 E018 12.9150911 0.0015065812 3.914443e-02 1.915630e-01 6 75817548 75817664 117 + 1.222 1.056 -0.597
ENSG00000196586 E019 0.1268540 0.0123277228 1.000000e+00   6 75819773 75819872 100 + 0.000 0.070 11.042
ENSG00000196586 E020 11.0363084 0.0012751486 3.886143e-03 4.160287e-02 6 75822782 75822851 70 + 1.204 0.958 -0.892
ENSG00000196586 E021 11.8098613 0.0012331694 2.959860e-02 1.617233e-01 6 75828540 75828613 74 + 1.195 1.013 -0.654
ENSG00000196586 E022 14.8169750 0.0009680522 2.247932e-04 4.606382e-03 6 75830416 75830545 130 + 1.338 1.062 -0.980
ENSG00000196586 E023 12.0020058 0.0012976743 5.996351e-04 1.005701e-02 6 75832842 75832947 106 + 1.256 0.975 -1.015
ENSG00000196586 E024 0.0000000       6 75834250 75834376 127 +      
ENSG00000196586 E025 9.7980517 0.0014364119 3.511968e-03 3.885200e-02 6 75835901 75835956 56 + 1.165 0.905 -0.956
ENSG00000196586 E026 12.9946561 0.0010389163 2.918360e-03 3.382012e-02 6 75840585 75840682 98 + 1.264 1.028 -0.847
ENSG00000196586 E027 17.3883362 0.0029180990 8.059549e-05 1.983951e-03 6 75841214 75841378 165 + 1.407 1.124 -0.996
ENSG00000196586 E028 9.3613212 0.0016641809 1.442658e-01 4.043973e-01 6 75844897 75844977 81 + 1.076 0.941 -0.496
ENSG00000196586 E029 0.1272623 0.0124087684 1.000000e+00   6 75844978 75844982 5 + 0.000 0.070 11.042
ENSG00000196586 E030 0.0000000       6 75846968 75846976 9 +      
ENSG00000196586 E031 17.7697895 0.0086688714 2.720605e-01 5.659023e-01 6 75848351 75848531 181 + 1.303 1.217 -0.304
ENSG00000196586 E032 16.9711928 0.0239449614 6.754425e-02 2.621759e-01 6 75855139 75855283 145 + 1.338 1.162 -0.620
ENSG00000196586 E033 21.9001468 0.0007389852 6.501738e-01 8.526542e-01 6 75857097 75857254 158 + 1.352 1.323 -0.100
ENSG00000196586 E034 13.8720613 0.0089335394 1.638569e-02 1.112610e-01 6 75858902 75858993 92 + 1.272 1.069 -0.725
ENSG00000196586 E035 17.9908486 0.0008426763 7.464769e-02 2.785661e-01 6 75861023 75861095 73 + 1.331 1.207 -0.436
ENSG00000196586 E036 25.1850780 0.0005442554 1.562667e-01 4.225429e-01 6 75862596 75862723 128 + 1.446 1.361 -0.294
ENSG00000196586 E037 21.3104487 0.0006384991 9.257350e-01 9.777267e-01 6 75866526 75866621 96 + 1.325 1.319 -0.018
ENSG00000196586 E038 33.6287442 0.0016165372 2.891204e-01 5.827885e-01 6 75866932 75867105 174 + 1.549 1.492 -0.196
ENSG00000196586 E039 0.0000000       6 75867431 75867523 93 +      
ENSG00000196586 E040 14.9671295 0.0009093278 5.819535e-01 8.138723e-01 6 75870647 75870685 39 + 1.204 1.162 -0.148
ENSG00000196586 E041 0.1272623 0.0124087684 1.000000e+00   6 75871295 75871392 98 + 0.000 0.070 11.042
ENSG00000196586 E042 21.1824840 0.0006525163 2.156734e-02 1.330146e-01 6 75873207 75873300 94 + 1.413 1.265 -0.516
ENSG00000196586 E043 25.0682331 0.0005173033 1.846696e-01 4.619437e-01 6 75879820 75879950 131 + 1.441 1.361 -0.275
ENSG00000196586 E044 15.6312721 0.0013442224 5.998314e-01 8.245853e-01 6 75880043 75880120 78 + 1.165 1.207 0.149
ENSG00000196586 E045 21.5344520 0.0006872041 7.631576e-01 9.076506e-01 6 75881689 75881818 130 + 1.338 1.319 -0.066
ENSG00000196586 E046 21.5761928 0.0017009636 6.249471e-01 8.385803e-01 6 75886004 75886094 91 + 1.303 1.337 0.120
ENSG00000196586 E047 41.0089966 0.0003617563 9.607715e-01 9.912235e-01 6 75886844 75886994 151 + 1.593 1.596 0.012
ENSG00000196586 E048 43.8448317 0.0089525458 1.997876e-01 4.815581e-01 6 75890057 75890209 153 + 1.672 1.598 -0.251
ENSG00000196586 E049 29.2047289 0.0005743227 6.000161e-01 8.247640e-01 6 75890210 75890265 56 + 1.472 1.443 -0.100
ENSG00000196586 E050 33.8467522 0.0004371426 7.270087e-01 8.908843e-01 6 75891228 75891306 79 + 1.501 1.521 0.068
ENSG00000196586 E051 54.1296568 0.0002716855 1.505354e-01 4.131112e-01 6 75892530 75892690 161 + 1.753 1.693 -0.201
ENSG00000196586 E052 13.8494135 0.0014292488 2.908541e-02 1.599890e-01 6 75893931 75894813 883 + 1.009 1.198 0.682
ENSG00000196586 E053 7.8200334 0.0244883200 5.426089e-01 7.897738e-01 6 75894814 75894840 27 + 0.874 0.941 0.256
ENSG00000196586 E054 5.2933141 0.0027047864 2.358340e-04 4.783555e-03 6 75894841 75895230 390 + 0.374 0.885 2.292
ENSG00000196586 E055 11.5853434 0.0072605429 2.305762e-01 5.190056e-01 6 75895231 75895260 30 + 1.145 1.035 -0.396
ENSG00000196586 E056 13.1203509 0.0013028436 3.900801e-03 4.171011e-02 6 75898373 75898411 39 + 1.264 1.035 -0.821
ENSG00000196586 E057 41.9255719 0.0003328155 3.674260e-01 6.560101e-01 6 75907605 75907708 104 + 1.633 1.591 -0.143
ENSG00000196586 E058 43.8778039 0.0004332184 9.075719e-02 3.128730e-01 6 75908496 75908627 132 + 1.566 1.649 0.284
ENSG00000196586 E059 1.6419817 0.0089141117 2.641620e-02 1.506770e-01 6 75911672 75911698 27 + 0.127 0.493 2.629
ENSG00000196586 E060 68.8398815 0.0059352039 4.979833e-04 8.717374e-03 6 75914063 75914281 219 + 1.688 1.866 0.601
ENSG00000196586 E061 467.1001378 0.0001033151 5.381510e-18 1.224668e-15 6 75914813 75919537 4725 + 2.563 2.675 0.371

Help

Please Click HERE to learn more details about the results from DEXseq.