ENSG00000196843

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000357485 ENSG00000196843 No_inf pgKDN_inf ARID5A protein_coding protein_coding 21.68295 32.84394 17.05114 0.7521101 0.7041459 -0.9453529 6.063056 6.503097 6.0629371 3.236898 2.66098761 -0.1009493 0.31766667 0.204225 0.369100 0.164875 0.83695530 0.03982515 FALSE TRUE
ENST00000412735 ENSG00000196843 No_inf pgKDN_inf ARID5A protein_coding nonsense_mediated_decay 21.68295 32.84394 17.05114 0.7521101 0.7041459 -0.9453529 11.286534 17.516450 9.4229399 1.690022 2.34225249 -0.8937545 0.50834167 0.530850 0.543600 0.012750 0.99324466 0.03982515 FALSE TRUE
ENST00000497920 ENSG00000196843 No_inf pgKDN_inf ARID5A protein_coding retained_intron 21.68295 32.84394 17.05114 0.7521101 0.7041459 -0.9453529 1.463316 3.564150 0.1137496 1.167758 0.06663471 -4.8521046 0.05340000 0.107825 0.006800 -0.101025 0.03982515 0.03982515 FALSE TRUE
MSTRG.16693.7 ENSG00000196843 No_inf pgKDN_inf ARID5A protein_coding   21.68295 32.84394 17.05114 0.7521101 0.7041459 -0.9453529 1.505218 2.815013 0.2695592 1.324515 0.26955919 -3.3370320 0.06373333 0.083150 0.014575 -0.068575 0.50741839 0.03982515 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000196843 E001 0.2452102 0.0163384322 0.568165663   2 96536743 96536751 9 + 0.130 0.069 -1.030
ENSG00000196843 E002 0.9711764 0.0114991193 0.085342853 0.30218497 2 96536752 96536766 15 + 0.439 0.180 -1.767
ENSG00000196843 E003 5.4220508 0.0028397431 0.244574706 0.53489756 2 96536767 96536830 64 + 0.863 0.737 -0.499
ENSG00000196843 E004 2.8995633 0.0488066799 0.013704922 0.09864691 2 96537345 96538321 977 + 0.230 0.662 2.362
ENSG00000196843 E005 1.5243198 0.1152864037 0.011646305 0.08884467 2 96540402 96540677 276 + 0.000 0.485 10.841
ENSG00000196843 E006 0.2441403 0.0163295797 0.568467282   2 96547390 96547401 12 + 0.130 0.069 -1.030
ENSG00000196843 E007 14.0418053 0.0018085919 0.031776477 0.16845218 2 96547402 96547517 116 + 1.250 1.090 -0.571
ENSG00000196843 E008 10.3795570 0.0014152352 0.391233409 0.67637217 2 96549321 96549459 139 + 1.073 1.003 -0.256
ENSG00000196843 E009 12.3786976 0.0025891215 0.748597062 0.90074143 2 96549753 96549805 53 + 1.110 1.090 -0.073
ENSG00000196843 E010 4.7974873 0.1040812359 0.005445627 0.05265408 2 96549806 96550187 382 + 0.312 0.845 2.515
ENSG00000196843 E011 19.9826528 0.0007898830 0.689916678 0.87259271 2 96550188 96550285 98 + 1.267 1.301 0.121
ENSG00000196843 E012 30.6615378 0.0004797508 0.110157727 0.34829695 2 96550574 96550733 160 + 1.521 1.443 -0.268
ENSG00000196843 E013 42.1640289 0.0004393819 0.757220711 0.90447903 2 96551099 96551326 228 + 1.608 1.601 -0.024
ENSG00000196843 E014 106.5553468 0.0001695753 0.781215639 0.91579908 2 96551327 96552210 884 + 1.989 2.004 0.049
ENSG00000196843 E015 52.7012652 0.0055254721 0.223023931 0.51044230 2 96552211 96552634 424 + 1.651 1.718 0.228

Help

Please Click HERE to learn more details about the results from DEXseq.