ENSG00000196961

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000354293 ENSG00000196961 No_inf pgKDN_inf AP2A1 protein_coding protein_coding 66.23697 59.59412 70.66565 1.725153 3.281411 0.2458013 36.213465 25.704520 44.489196 0.7069986 0.7538362 0.79119606 0.54205833 0.43155 0.63270 0.20115 0.002553986 0.002553986 FALSE TRUE
ENST00000594838 ENSG00000196961 No_inf pgKDN_inf AP2A1 protein_coding retained_intron 66.23697 59.59412 70.66565 1.725153 3.281411 0.2458013 21.944755 21.097376 21.962250 2.1560240 2.7921242 0.05793539 0.33069167 0.35185 0.30745 -0.04440 0.834289373 0.002553986 FALSE FALSE
MSTRG.15473.6 ENSG00000196961 No_inf pgKDN_inf AP2A1 protein_coding   66.23697 59.59412 70.66565 1.725153 3.281411 0.2458013 3.197445 5.457958 1.615984 0.9459840 0.6434306 -1.74968929 0.05098333 0.09230 0.02395 -0.06835 0.241896323 0.002553986 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000196961 E001 0.4812268 0.0270089733 4.363444e-01   19 49767001 49767006 6 + 0.220 0.105 -1.267
ENSG00000196961 E002 8.3960073 0.0119124326 6.934922e-01 8.747995e-01 19 49767007 49767135 129 + 0.990 0.951 -0.146
ENSG00000196961 E003 10.1404796 0.0433429416 5.267914e-02 2.280803e-01 19 49767136 49767200 65 + 1.137 0.909 -0.839
ENSG00000196961 E004 17.6999557 0.0008218797 4.203700e-02 1.995171e-01 19 49781757 49781825 69 + 1.330 1.190 -0.494
ENSG00000196961 E005 13.6630408 0.0009511461 9.993360e-01 1.000000e+00 19 49781947 49781970 24 + 1.164 1.166 0.007
ENSG00000196961 E006 28.7576695 0.0045103947 8.025322e-02 2.908074e-01 19 49781971 49782089 119 + 1.519 1.413 -0.364
ENSG00000196961 E007 42.6783706 0.0004122428 1.391175e-01 3.965979e-01 19 49782531 49782724 194 + 1.668 1.603 -0.223
ENSG00000196961 E008 33.3578122 0.0004731985 1.117540e-02 8.651274e-02 19 49791935 49792064 130 + 1.590 1.460 -0.444
ENSG00000196961 E009 19.1451921 0.0007520645 2.969061e-02 1.620291e-01 19 49792991 49793035 45 + 1.364 1.219 -0.508
ENSG00000196961 E010 21.9560649 0.0006542743 3.824971e-02 1.888293e-01 19 49793036 49793092 57 + 1.415 1.286 -0.449
ENSG00000196961 E011 25.7536196 0.0011708331 9.155752e-01 9.735314e-01 19 49795630 49795718 89 + 1.422 1.431 0.030
ENSG00000196961 E012 13.7514144 0.0010095637 5.159186e-01 7.717788e-01 19 49795719 49795738 20 + 1.189 1.141 -0.172
ENSG00000196961 E013 4.6147108 0.0141881370 2.904491e-04 5.657306e-03 19 49796103 49797562 1460 + 0.473 0.937 1.955
ENSG00000196961 E014 0.8628877 0.1493726015 5.768921e-01 8.108331e-01 19 49798669 49798801 133 + 0.220 0.321 0.733
ENSG00000196961 E015 38.6948069 0.0017391948 2.811428e-01 5.744055e-01 19 49798802 49798952 151 + 1.621 1.569 -0.177
ENSG00000196961 E016 43.5589268 0.0033995427 6.676395e-03 6.103131e-02 19 49799327 49799495 169 + 1.706 1.569 -0.465
ENSG00000196961 E017 40.0234688 0.0004579314 9.598914e-01 9.907448e-01 19 49799629 49799766 138 + 1.612 1.612 0.000
ENSG00000196961 E018 29.2382430 0.0005386498 2.290311e-01 5.177102e-01 19 49799968 49800017 50 + 1.447 1.515 0.233
ENSG00000196961 E019 36.6105179 0.0003736407 9.021783e-01 9.686671e-01 19 49800018 49800096 79 + 1.570 1.579 0.028
ENSG00000196961 E020 29.8836604 0.0129298899 9.168971e-01 9.738849e-01 19 49800097 49800150 54 + 1.492 1.484 -0.026
ENSG00000196961 E021 1.2415328 0.1131113267 1.594887e-01 4.268719e-01 19 49800692 49800960 269 + 0.219 0.464 1.541
ENSG00000196961 E022 25.2892671 0.0022817229 1.865145e-01 4.644941e-01 19 49800961 49800999 39 + 1.453 1.374 -0.273
ENSG00000196961 E023 28.6759463 0.0004878053 7.878639e-02 2.877346e-01 19 49801000 49801058 59 + 1.513 1.417 -0.329
ENSG00000196961 E024 18.2514023 0.0013756460 3.321110e-01 6.242447e-01 19 49801390 49801402 13 + 1.312 1.247 -0.227
ENSG00000196961 E025 50.6645621 0.0002930813 7.126722e-01 8.839404e-01 19 49801403 49801546 144 + 1.704 1.721 0.060
ENSG00000196961 E026 32.8236205 0.0008325372 2.012180e-01 4.834719e-01 19 49801547 49801621 75 + 1.557 1.492 -0.223
ENSG00000196961 E027 0.2537079 0.2423156553 2.248160e-01   19 49801622 49801721 100 + 0.000 0.189 11.955
ENSG00000196961 E028 44.0064656 0.0004083286 9.678120e-02 3.239897e-01 19 49801722 49801889 168 + 1.684 1.612 -0.247
ENSG00000196961 E029 38.1697445 0.0007941220 1.100323e-01 3.481018e-01 19 49801981 49802141 161 + 1.625 1.549 -0.260
ENSG00000196961 E030 0.7629136 0.0194501481 4.697835e-03 4.739488e-02 19 49802142 49802521 380 + 0.000 0.422 13.540
ENSG00000196961 E031 0.0000000       19 49802522 49802533 12 +      
ENSG00000196961 E032 0.1268540 0.0123101587 4.332318e-01   19 49802534 49802599 66 + 0.000 0.105 10.955
ENSG00000196961 E033 2.2198521 0.0068164770 1.669170e-01 4.373926e-01 19 49802600 49802948 349 + 0.404 0.603 0.970
ENSG00000196961 E034 23.4701920 0.0006742612 3.004949e-01 5.933330e-01 19 49802949 49803005 57 + 1.415 1.354 -0.211
ENSG00000196961 E035 0.3804973 0.0158957261 6.794481e-02   19 49803006 49803106 101 + 0.000 0.260 12.540
ENSG00000196961 E036 35.8626129 0.0003959517 1.216768e-01 3.692517e-01 19 49803107 49803189 83 + 1.527 1.606 0.268
ENSG00000196961 E037 1.1157456 0.0110412032 1.886818e-01 4.671914e-01 19 49803190 49803286 97 + 0.220 0.422 1.318
ENSG00000196961 E038 62.1452082 0.0002309305 8.319709e-02 2.972411e-01 19 49803287 49803376 90 + 1.767 1.834 0.227
ENSG00000196961 E039 18.2648290 0.0007592307 1.028992e-17 2.246869e-15 19 49803377 49804540 1164 + 0.880 1.515 2.269
ENSG00000196961 E040 8.3673026 0.0413635021 2.067320e-05 6.345978e-04 19 49804876 49805452 577 + 0.632 1.182 2.111
ENSG00000196961 E041 72.4154271 0.0002363638 4.386659e-01 7.147265e-01 19 49805453 49805576 124 + 1.851 1.880 0.098
ENSG00000196961 E042 0.8517450 0.1475138659 9.568977e-01 9.897505e-01 19 49805577 49805660 84 + 0.273 0.260 -0.097
ENSG00000196961 E043 46.0693245 0.0022159393 4.030497e-01 6.861048e-01 19 49805661 49805724 64 + 1.652 1.693 0.141
ENSG00000196961 E044 37.7196357 0.0004489006 6.440251e-01 8.492134e-01 19 49805725 49805777 53 + 1.575 1.600 0.084
ENSG00000196961 E045 0.7269737 0.0139374235 5.757777e-01 8.101746e-01 19 49805778 49805871 94 + 0.273 0.189 -0.682
ENSG00000196961 E046 35.6707462 0.0013727749 4.372402e-01 7.135284e-01 19 49805872 49805941 70 + 1.580 1.543 -0.129
ENSG00000196961 E047 0.7543544 0.0141089629 5.363533e-02 2.305699e-01 19 49805942 49806118 177 + 0.086 0.374 2.640
ENSG00000196961 E048 51.3907595 0.0002905122 7.647239e-01 9.085086e-01 19 49806119 49806253 135 + 1.711 1.726 0.050
ENSG00000196961 E049 12.8847738 0.0011487943 2.615999e-12 3.243478e-10 19 49806254 49806680 427 + 0.765 1.364 2.198
ENSG00000196961 E050 51.3014778 0.0002872175 3.024171e-02 1.635819e-01 19 49806681 49807114 434 + 1.672 1.764 0.311

Help

Please Click HERE to learn more details about the results from DEXseq.