ENSG00000197170

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000356126 ENSG00000197170 No_inf pgKDN_inf PSMD12 protein_coding protein_coding 42.95958 34.11481 49.06086 1.324641 1.734712 0.5240453 11.786807 14.035840 11.017717 0.1561015 0.326312 -0.3490088 0.2884917 0.413250 0.226225 -0.187025 0.02688467 0.02688467 FALSE TRUE
ENST00000357146 ENSG00000197170 No_inf pgKDN_inf PSMD12 protein_coding protein_coding 42.95958 34.11481 49.06086 1.324641 1.734712 0.5240453 6.281107 1.974510 9.461602 1.1423653 2.300231 2.2548255 0.1384167 0.059750 0.188825 0.129075 0.37646899 0.02688467 FALSE TRUE
ENST00000584008 ENSG00000197170 No_inf pgKDN_inf PSMD12 protein_coding nonsense_mediated_decay 42.95958 34.11481 49.06086 1.324641 1.734712 0.5240453 11.357745 11.906646 13.332104 2.1083819 1.400461 0.1630080 0.2704417 0.344525 0.275225 -0.069300 0.82503655 0.02688467 FALSE TRUE
ENST00000584289 ENSG00000197170 No_inf pgKDN_inf PSMD12 protein_coding retained_intron 42.95958 34.11481 49.06086 1.324641 1.734712 0.5240453 12.076780 5.201053 15.249436 0.9255792 1.176816 1.5500549 0.2691917 0.153625 0.309725 0.156100 0.10334717 0.02688467 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000197170 E001 116.9568683 0.0002373566 6.976414e-12 8.091740e-10 17 67337916 67339802 1887 - 1.972 2.153 0.608
ENSG00000197170 E002 57.5905637 0.0028791305 3.480348e-01 6.385528e-01 17 67339803 67340773 971 - 1.747 1.788 0.138
ENSG00000197170 E003 57.4174716 0.0003531118 5.087277e-01 7.669094e-01 17 67340774 67340974 201 - 1.779 1.754 -0.084
ENSG00000197170 E004 42.6311240 0.0005935637 4.775758e-01 7.438366e-01 17 67340975 67341052 78 - 1.655 1.624 -0.106
ENSG00000197170 E005 42.2932827 0.0003488679 2.569339e-01 5.492024e-01 17 67342186 67342263 78 - 1.610 1.661 0.176
ENSG00000197170 E006 0.2539903 0.0159904255 2.202691e-01   17 67342264 67342484 221 - 0.000 0.178 11.305
ENSG00000197170 E007 58.2428870 0.0002645427 9.180943e-01 9.742548e-01 17 67344606 67344780 175 - 1.770 1.775 0.016
ENSG00000197170 E008 0.1187032 0.0117855723 5.754630e-01   17 67345612 67345744 133 - 0.092 0.000 -10.281
ENSG00000197170 E009 36.0648365 0.0003992540 7.716694e-02 2.841523e-01 17 67345745 67345857 113 - 1.610 1.524 -0.291
ENSG00000197170 E010 44.3706264 0.0008026531 9.575813e-02 3.222851e-01 17 67347116 67347250 135 - 1.692 1.619 -0.250
ENSG00000197170 E011 54.9020671 0.0002731907 1.359721e-01 3.920519e-01 17 67347336 67347485 150 - 1.775 1.718 -0.195
ENSG00000197170 E012 37.9888018 0.0003578817 4.732471e-01 7.403013e-01 17 67348550 67348654 105 - 1.607 1.574 -0.113
ENSG00000197170 E013 19.2454763 0.0007479204 1.371340e-01 3.941900e-01 17 67350229 67350257 29 - 1.352 1.255 -0.341
ENSG00000197170 E014 27.0286349 0.0005075450 5.381494e-02 2.307604e-01 17 67350258 67350298 41 - 1.498 1.390 -0.371
ENSG00000197170 E015 23.1644158 0.0006570836 2.013132e-01 4.836409e-01 17 67350299 67350336 38 - 1.420 1.343 -0.266
ENSG00000197170 E016 0.1176306 0.0117687505 5.753964e-01   17 67355341 67355422 82 - 0.092 0.000 -10.280
ENSG00000197170 E017 0.2459004 0.0165061914 9.583515e-01   17 67357152 67357302 151 - 0.092 0.098 0.101
ENSG00000197170 E018 39.3254341 0.0003568431 3.935854e-01 6.784593e-01 17 67357303 67357431 129 - 1.625 1.586 -0.133
ENSG00000197170 E019 0.2459004 0.0165061914 9.583515e-01   17 67357432 67357518 87 - 0.092 0.098 0.101
ENSG00000197170 E020 17.0216183 0.0013473667 7.531105e-01 9.028207e-01 17 67357519 67357578 60 - 1.244 1.267 0.080
ENSG00000197170 E021 0.4991354 0.0153050948 2.879297e-01   17 67361095 67361261 167 - 0.092 0.246 1.686
ENSG00000197170 E022 0.4900408 0.0158277217 9.469609e-01   17 67362776 67362892 117 - 0.168 0.178 0.101
ENSG00000197170 E023 26.0051341 0.0007847966 1.176349e-02 8.944902e-02 17 67366412 67366605 194 - 1.498 1.353 -0.501

Help

Please Click HERE to learn more details about the results from DEXseq.