ENSG00000197324

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000359591 ENSG00000197324 No_inf pgKDN_inf LRP10 protein_coding protein_coding 94.30971 77.86056 101.913 0.6028343 0.7596942 0.3883292 72.38437 76.3841007 71.29523 0.4903636 1.316453 -0.09945337 0.7848417 0.981275 0.69950 -0.281775 6.336327e-12 6.336327e-12 FALSE TRUE
ENST00000553002 ENSG00000197324 No_inf pgKDN_inf LRP10 protein_coding retained_intron 94.30971 77.86056 101.913 0.6028343 0.7596942 0.3883292 21.18348 0.7885519 29.74462 0.7885519 1.116910 5.21958376 0.2071833 0.009925 0.29185 0.281925 1.668283e-05 6.336327e-12 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000197324 E001 1.2162283 2.403110e-01 4.245478e-01 7.037608e-01 14 22871740 22871773 34 + 0.404 0.288 -0.708
ENSG00000197324 E002 2.0672570 6.012275e-02 4.205839e-01 6.998573e-01 14 22871774 22871781 8 + 0.551 0.422 -0.638
ENSG00000197324 E003 186.3013303 2.668730e-04 1.315809e-11 1.469293e-09 14 22871782 22872303 522 + 2.347 2.194 -0.513
ENSG00000197324 E004 50.0653790 5.222302e-03 6.989408e-02 2.674609e-01 14 22872304 22872337 34 + 1.755 1.661 -0.321
ENSG00000197324 E005 53.5588988 2.964422e-04 3.593014e-03 3.946754e-02 14 22872738 22872782 45 + 1.796 1.676 -0.407
ENSG00000197324 E006 0.8691196 3.295270e-02 3.098679e-01 6.031403e-01 14 22873085 22873310 226 + 0.179 0.337 1.198
ENSG00000197324 E007 91.9201905 1.956413e-04 8.264643e-09 5.975138e-07 14 22873311 22873446 136 + 2.056 1.873 -0.614
ENSG00000197324 E008 67.0728564 1.934236e-03 5.697104e-06 2.103132e-04 14 22875055 22875135 81 + 1.922 1.736 -0.626
ENSG00000197324 E009 85.5419022 1.802505e-04 2.762604e-04 5.437794e-03 14 22875136 22875245 110 + 1.996 1.877 -0.400
ENSG00000197324 E010 98.6309438 1.870519e-03 2.192862e-02 1.344538e-01 14 22875355 22875465 111 + 2.039 1.958 -0.270
ENSG00000197324 E011 546.2477342 5.390270e-05 4.499666e-09 3.398949e-07 14 22875466 22876299 834 + 2.774 2.702 -0.241
ENSG00000197324 E012 122.3971945 1.288135e-04 6.992031e-03 6.299878e-02 14 22876300 22876372 73 + 2.128 2.054 -0.248
ENSG00000197324 E013 93.5322440 1.742452e-04 3.964463e-04 7.241475e-03 14 22876689 22876716 28 + 2.031 1.919 -0.373
ENSG00000197324 E014 161.0863930 3.456963e-04 4.314777e-03 4.473533e-02 14 22876717 22876818 102 + 2.245 2.174 -0.236
ENSG00000197324 E015 170.1191002 1.233258e-04 1.493006e-01 4.115499e-01 14 22876940 22877053 114 + 2.250 2.216 -0.113
ENSG00000197324 E016 331.9643783 7.334244e-04 2.121409e-01 4.973532e-01 14 22877054 22877426 373 + 2.534 2.509 -0.082
ENSG00000197324 E017 219.9091553 9.406445e-05 9.540164e-01 9.886732e-01 14 22877427 22877596 170 + 2.344 2.342 -0.006
ENSG00000197324 E018 558.1798625 1.403404e-04 1.374574e-15 2.446741e-13 14 22877597 22877983 387 + 2.689 2.790 0.335
ENSG00000197324 E019 208.1515507 1.101152e-04 1.826521e-11 1.998207e-09 14 22877984 22879198 1215 + 2.237 2.378 0.471
ENSG00000197324 E020 450.2632758 5.207344e-05 5.075712e-47 6.676913e-44 14 22879199 22881713 2515 + 2.533 2.734 0.668

Help

Please Click HERE to learn more details about the results from DEXseq.