ENSG00000197448

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000358406 ENSG00000197448 No_inf pgKDN_inf GSTK1 protein_coding protein_coding 97.59325 107.5296 95.63351 1.489991 0.7674203 -0.169129 61.10274 56.57631 67.20321 2.248138 2.252249 0.2482917 0.6313583 0.525975 0.703425 0.17745 0.007297103 0.007297103 FALSE TRUE
ENST00000479303 ENSG00000197448 No_inf pgKDN_inf GSTK1 protein_coding protein_coding 97.59325 107.5296 95.63351 1.489991 0.7674203 -0.169129 22.91896 34.29659 15.44874 2.034517 2.315811 -1.1500629 0.2305250 0.318725 0.161075 -0.15765 0.019055387 0.007297103 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000197448 E001 0.000000       7 143244093 143244276 184 +      
ENSG00000197448 E002 0.000000       7 143263148 143263207 60 +      
ENSG00000197448 E003 1.088526 0.0282462027 1.691209e-01 4.407309e-01 7 143263429 143263440 12 + 0.429 0.215 -1.395
ENSG00000197448 E004 1.215789 0.0411738588 3.103483e-01 6.035036e-01 7 143263441 143263450 10 + 0.429 0.268 -0.980
ENSG00000197448 E005 1.461346 0.0101625768 2.990114e-01 5.918772e-01 7 143263451 143263455 5 + 0.472 0.315 -0.881
ENSG00000197448 E006 5.837790 0.0029089035 3.749082e-02 1.866374e-01 7 143263456 143263470 15 + 0.947 0.722 -0.881
ENSG00000197448 E007 8.505159 0.0016635577 5.077932e-03 5.021510e-02 7 143263471 143263486 16 + 1.107 0.844 -0.980
ENSG00000197448 E008 11.205077 0.0015266339 1.094850e-02 8.533187e-02 7 143263487 143263495 9 + 1.193 0.979 -0.774
ENSG00000197448 E009 38.949176 0.0003900390 1.823614e-02 1.192758e-01 7 143263496 143263585 90 + 1.657 1.546 -0.377
ENSG00000197448 E010 7.498904 0.0070970043 7.862930e-04 1.244512e-02 7 143263586 143264085 500 + 0.667 1.043 1.459
ENSG00000197448 E011 46.202518 0.0003126164 3.060774e-01 5.992617e-01 7 143264086 143264167 82 + 1.693 1.649 -0.149
ENSG00000197448 E012 7.125430 0.0019645369 4.920646e-04 8.624963e-03 7 143264168 143264547 380 + 0.640 1.025 1.511
ENSG00000197448 E013 83.489983 0.0002532817 4.267133e-01 7.053128e-01 7 143264548 143264676 129 + 1.935 1.910 -0.084
ENSG00000197448 E014 11.567542 0.0011894551 9.293462e-01 9.792288e-01 7 143264677 143264991 315 + 1.097 1.090 -0.025
ENSG00000197448 E015 89.184292 0.0005251608 1.350466e-01 3.907302e-01 7 143264992 143265092 101 + 1.975 1.929 -0.157
ENSG00000197448 E016 34.227128 0.0007748698 1.082137e-07 6.268955e-06 7 143265093 143265260 168 + 1.349 1.638 0.993
ENSG00000197448 E017 53.390528 0.0002868030 2.784380e-01 5.716875e-01 7 143265261 143265296 36 + 1.702 1.747 0.151
ENSG00000197448 E018 97.505948 0.0001711887 4.203397e-01 6.997484e-01 7 143267617 143267733 117 + 2.000 1.977 -0.078
ENSG00000197448 E019 72.529859 0.0002129423 3.759565e-01 6.631619e-01 7 143268091 143268184 94 + 1.877 1.847 -0.101
ENSG00000197448 E020 105.959539 0.0001813456 9.804601e-01 9.978172e-01 7 143268788 143268943 156 + 2.023 2.023 -0.001
ENSG00000197448 E021 66.465294 0.0002248718 9.219475e-01 9.757519e-01 7 143268944 143269115 172 + 1.820 1.824 0.013
ENSG00000197448 E022 56.345599 0.0003486889 1.826869e-04 3.885267e-03 7 143269292 143270854 1563 + 1.657 1.809 0.515

Help

Please Click HERE to learn more details about the results from DEXseq.