ENSG00000197530

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000378712 ENSG00000197530 No_inf pgKDN_inf MIB2 protein_coding protein_coding 22.46641 31.94881 12.22364 1.570414 2.162432 -1.38536 0.1567332 0.0000000 0.4701996 0.0000000 0.4701996 5.5855622 0.01690000 0.000000 0.050700 0.050700 0.751351209 0.000383394 FALSE TRUE
ENST00000464570 ENSG00000197530 No_inf pgKDN_inf MIB2 protein_coding retained_intron 22.46641 31.94881 12.22364 1.570414 2.162432 -1.38536 1.4334363 1.9649939 1.0020156 1.9649939 1.0020156 -0.9646167 0.05718333 0.054300 0.057675 0.003375 0.887505145 0.000383394   FALSE
ENST00000470373 ENSG00000197530 No_inf pgKDN_inf MIB2 protein_coding retained_intron 22.46641 31.94881 12.22364 1.570414 2.162432 -1.38536 1.4206649 0.0000000 1.3175248 0.0000000 1.3175248 7.0525950 0.06667500 0.000000 0.075825 0.075825 0.698786924 0.000383394 FALSE FALSE
ENST00000473511 ENSG00000197530 No_inf pgKDN_inf MIB2 protein_coding retained_intron 22.46641 31.94881 12.22364 1.570414 2.162432 -1.38536 1.6658945 3.1043752 0.4510028 1.0437981 0.4510028 -2.7560954 0.06456667 0.102000 0.031850 -0.070150 0.571487849 0.000383394 TRUE FALSE
ENST00000479659 ENSG00000197530 No_inf pgKDN_inf MIB2 protein_coding retained_intron 22.46641 31.94881 12.22364 1.570414 2.162432 -1.38536 1.5737914 3.1665494 0.7555124 0.2513367 0.2983540 -2.0529627 0.06909167 0.100075 0.073100 -0.026975 0.808380401 0.000383394 FALSE TRUE
ENST00000489635 ENSG00000197530 No_inf pgKDN_inf MIB2 protein_coding nonsense_mediated_decay 22.46641 31.94881 12.22364 1.570414 2.162432 -1.38536 1.4636889 0.0000000 2.6988771 0.0000000 1.6133023 8.0815511 0.10140833 0.000000 0.231250 0.231250 0.315175184 0.000383394 FALSE TRUE
ENST00000505370 ENSG00000197530 No_inf pgKDN_inf MIB2 protein_coding retained_intron 22.46641 31.94881 12.22364 1.570414 2.162432 -1.38536 2.1658598 4.1043350 0.0000000 0.7470661 0.0000000 -8.6845154 0.07772500 0.127650 0.000000 -0.127650 0.000383394 0.000383394 FALSE FALSE
ENST00000512004 ENSG00000197530 No_inf pgKDN_inf MIB2 protein_coding protein_coding_CDS_not_defined 22.46641 31.94881 12.22364 1.570414 2.162432 -1.38536 1.4275662 2.6542921 0.2160337 1.0220276 0.2160337 -3.5591424 0.05304167 0.084175 0.012425 -0.071750 0.332749365 0.000383394   FALSE
MSTRG.85.10 ENSG00000197530 No_inf pgKDN_inf MIB2 protein_coding   22.46641 31.94881 12.22364 1.570414 2.162432 -1.38536 3.5047277 5.6980640 1.2740850 1.0173289 1.2740850 -2.1522609 0.13566667 0.179925 0.073325 -0.106600 0.271064202 0.000383394 FALSE TRUE
MSTRG.85.20 ENSG00000197530 No_inf pgKDN_inf MIB2 protein_coding   22.46641 31.94881 12.22364 1.570414 2.162432 -1.38536 0.3836045 0.2346246 0.5637851 0.2346246 0.4241808 1.2299411 0.02985000 0.006475 0.067900 0.061425 0.699041012 0.000383394 FALSE TRUE
MSTRG.85.33 ENSG00000197530 No_inf pgKDN_inf MIB2 protein_coding   22.46641 31.94881 12.22364 1.570414 2.162432 -1.38536 0.2788651 0.2050809 0.4942321 0.2050809 0.4942321 1.2292086 0.02448333 0.006525 0.061150 0.054625 0.878716266 0.000383394 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000197530 E001 0.0000000       1 1615454 1615495 42 +      
ENSG00000197530 E002 0.0000000       1 1615496 1615499 4 +      
ENSG00000197530 E003 0.0000000       1 1615500 1615513 14 +      
ENSG00000197530 E004 0.0000000       1 1615514 1615515 2 +      
ENSG00000197530 E005 0.0000000       1 1615516 1615529 14 +      
ENSG00000197530 E006 0.0000000       1 1615530 1615633 104 +      
ENSG00000197530 E007 0.5080420 0.0158984294 0.28476530 0.57849756 1 1615873 1615878 6 + 0.000 0.208 11.099
ENSG00000197530 E008 0.7529350 0.0142443038 0.53845428 0.78712544 1 1615879 1615886 8 + 0.143 0.248 0.984
ENSG00000197530 E009 0.7529350 0.0142443038 0.53845428 0.78712544 1 1615887 1615904 18 + 0.143 0.248 0.984
ENSG00000197530 E010 1.0062960 0.0114428347 0.30176037 0.59498549 1 1615905 1615913 9 + 0.143 0.318 1.469
ENSG00000197530 E011 1.3681929 0.0097765971 0.95260468 0.98825179 1 1615914 1615967 54 + 0.336 0.349 0.077
ENSG00000197530 E012 2.8827253 0.0050510264 0.23498958 0.52414922 1 1615968 1616100 133 + 0.408 0.594 0.909
ENSG00000197530 E013 0.1187032 0.0117575323 0.18617339   1 1616274 1616309 36 + 0.143 0.000 -14.398
ENSG00000197530 E014 0.1187032 0.0117575323 0.18617339   1 1616310 1616310 1 + 0.143 0.000 -14.398
ENSG00000197530 E015 1.1275823 0.1563581790 0.72755023 0.89128456 1 1616311 1616507 197 + 0.250 0.318 0.469
ENSG00000197530 E016 2.2595674 0.0577332200 0.31069137 0.60380616 1 1616508 1616511 4 + 0.336 0.520 0.984
ENSG00000197530 E017 5.2348059 0.0205399716 0.82021983 0.93472513 1 1616512 1616614 103 + 0.723 0.761 0.156
ENSG00000197530 E018 2.1235206 0.0231462601 0.68967844 0.87243449 1 1616615 1617077 463 + 0.408 0.477 0.362
ENSG00000197530 E019 2.0156518 0.0106651987 0.13856576 0.39586212 1 1617078 1617407 330 + 0.250 0.499 1.469
ENSG00000197530 E020 0.6189413 0.1383070529 0.60348995 0.82699604 1 1617408 1617515 108 + 0.250 0.165 -0.754
ENSG00000197530 E021 0.5085150 0.0157995032 0.28499282 0.57871999 1 1617516 1617559 44 + 0.000 0.208 13.569
ENSG00000197530 E022 0.6350220 0.0143017903 0.18173147 0.45773544 1 1617560 1617576 17 + 0.000 0.248 13.837
ENSG00000197530 E023 1.1424993 0.0106444988 0.03630373 0.18309382 1 1617577 1617715 139 + 0.000 0.378 14.517
ENSG00000197530 E024 3.9099859 0.0081970404 0.01319738 0.09627854 1 1617716 1619210 1495 + 0.336 0.725 1.884
ENSG00000197530 E025 2.2777245 0.0107051999 0.01581141 0.10885903 1 1623122 1623388 267 + 0.143 0.558 2.749
ENSG00000197530 E026 0.8809224 0.0132890042 0.40467439 0.68741953 1 1623389 1623430 42 + 0.143 0.284 1.247
ENSG00000197530 E027 3.6288949 0.0039817120 0.36427166 0.65303732 1 1623431 1623482 52 + 0.523 0.657 0.600
ENSG00000197530 E028 7.6158137 0.0018711629 0.36490117 0.65335923 1 1623483 1623580 98 + 0.810 0.916 0.409
ENSG00000197530 E029 8.8588884 0.0018687143 0.43441170 0.71170804 1 1623581 1623679 99 + 0.882 0.969 0.329
ENSG00000197530 E030 3.7559392 0.0107530044 0.32564393 0.61816415 1 1623680 1623699 20 + 0.523 0.672 0.662
ENSG00000197530 E031 5.6970639 0.0239214525 0.35768261 0.64723131 1 1623774 1623801 28 + 0.859 0.750 -0.432
ENSG00000197530 E032 12.3746874 0.0090557078 0.11081900 0.34940440 1 1623802 1623945 144 + 1.176 1.035 -0.508
ENSG00000197530 E033 2.1459641 0.0765987760 0.03526104 0.17981669 1 1623946 1624209 264 + 0.143 0.539 2.661
ENSG00000197530 E034 0.6348346 0.1360042061 0.22365573 0.51121581 1 1624744 1624794 51 + 0.000 0.248 13.736
ENSG00000197530 E035 7.3731204 0.0019526314 0.29035388 0.58399949 1 1624795 1624901 107 + 0.782 0.907 0.485
ENSG00000197530 E036 0.5080420 0.0158984294 0.28476530 0.57849756 1 1624965 1624990 26 + 0.000 0.208 13.569
ENSG00000197530 E037 10.0482706 0.0016089704 0.42671154 0.70531282 1 1624991 1625086 96 + 1.046 0.976 -0.258
ENSG00000197530 E038 9.0070721 0.0017256439 0.03242923 0.17060197 1 1625087 1625185 99 + 1.089 0.891 -0.737
ENSG00000197530 E039 11.4377153 0.0012657901 0.78481088 0.91700405 1 1625286 1625428 143 + 1.061 1.042 -0.071
ENSG00000197530 E040 1.7684891 0.0076080592 0.05092838 0.22332546 1 1625429 1625545 117 + 0.143 0.477 2.362
ENSG00000197530 E041 3.1408068 0.0079855418 0.16205102 0.43041760 1 1625546 1625557 12 + 0.408 0.627 1.054
ENSG00000197530 E042 3.5969864 0.1138491764 0.59859991 0.82404311 1 1625558 1625566 9 + 0.690 0.594 -0.414
ENSG00000197530 E043 7.3063489 0.0021353468 0.20997968 0.49441386 1 1625567 1625653 87 + 0.963 0.836 -0.483
ENSG00000197530 E044 8.6663269 0.0018343208 0.01791970 0.11799657 1 1625654 1626366 713 + 0.723 0.997 1.060
ENSG00000197530 E045 6.5322026 0.0022865039 0.03108749 0.16617173 1 1626367 1626649 283 + 0.614 0.891 1.121
ENSG00000197530 E046 11.3565472 0.0012106777 0.02169015 0.13359518 1 1626650 1626754 105 + 1.176 0.983 -0.701
ENSG00000197530 E047 5.9608657 0.0042902338 0.63699803 0.84503768 1 1626837 1626859 23 + 0.835 0.784 -0.201
ENSG00000197530 E048 16.2215601 0.0008927388 0.11268185 0.35314050 1 1626860 1626999 140 + 1.268 1.153 -0.404
ENSG00000197530 E049 0.6251694 0.0594210184 0.72549706 0.88982335 1 1627000 1627073 74 + 0.143 0.208 0.662
ENSG00000197530 E050 15.3046090 0.0008850886 0.92251358 0.97610200 1 1627074 1627207 134 + 1.165 1.163 -0.008
ENSG00000197530 E051 13.9665063 0.0010631833 0.46289542 0.73303781 1 1627296 1627444 149 + 1.075 1.144 0.247
ENSG00000197530 E052 1.5040166 0.3975530659 0.57832383 0.81155533 1 1627445 1627459 15 + 0.250 0.404 0.981
ENSG00000197530 E053 2.4948310 0.2381792704 0.86244366 0.95254379 1 1627460 1627521 62 + 0.470 0.519 0.244
ENSG00000197530 E054 4.4994639 0.0031646143 0.42682030 0.70540313 1 1627522 1627672 151 + 0.614 0.725 0.469
ENSG00000197530 E055 19.6322105 0.0007654387 0.63723174 0.84516063 1 1627673 1627829 157 + 1.285 1.257 -0.099
ENSG00000197530 E056 0.2442663 0.0167695281 0.45929887   1 1627830 1627830 1 + 0.143 0.062 -1.338
ENSG00000197530 E057 8.1484588 0.0437202140 0.21907582 0.50574386 1 1628019 1628034 16 + 1.031 0.864 -0.625
ENSG00000197530 E058 20.9721313 0.0011204319 0.34248636 0.63393710 1 1628035 1628179 145 + 1.335 1.275 -0.208
ENSG00000197530 E059 3.2720353 0.0082504138 0.04375609 0.20429555 1 1628180 1628272 93 + 0.336 0.657 1.600
ENSG00000197530 E060 16.4128513 0.0021351917 0.70585728 0.88060509 1 1628273 1628399 127 + 1.209 1.185 -0.085
ENSG00000197530 E061 0.6348960 0.0142422211 0.18183575 0.45787054 1 1628400 1628488 89 + 0.000 0.248 13.837
ENSG00000197530 E062 19.4061784 0.0007803435 0.82706134 0.93741561 1 1628489 1628722 234 + 1.268 1.257 -0.036
ENSG00000197530 E063 1.3807522 0.0095238540 0.45019420 0.72365434 1 1629034 1629105 72 + 0.250 0.378 0.831
ENSG00000197530 E064 1.0084707 0.0129106721 0.30300544 0.59614676 1 1629106 1629132 27 + 0.143 0.318 1.469
ENSG00000197530 E065 14.0454164 0.0011732779 0.62889109 0.84086004 1 1629133 1629311 179 + 1.153 1.119 -0.122
ENSG00000197530 E066 1.3671579 0.0096024954 0.95446368 0.98887944 1 1629312 1629384 73 + 0.336 0.349 0.077
ENSG00000197530 E067 4.3351240 0.0991095961 0.55937059 0.80050133 1 1629385 1629404 20 + 0.754 0.657 -0.400
ENSG00000197530 E068 6.5880149 0.0033915885 0.73123811 0.89325394 1 1629405 1629472 68 + 0.859 0.826 -0.129
ENSG00000197530 E069 3.9767809 0.0038402530 0.69493107 0.87538333 1 1629473 1629487 15 + 0.690 0.642 -0.201
ENSG00000197530 E070 8.1021077 0.0019931370 0.72911753 0.89200270 1 1629488 1629566 79 + 0.882 0.924 0.159
ENSG00000197530 E071 0.1271363 0.0123901058 1.00000000   1 1629567 1629638 72 + 0.000 0.062 11.812
ENSG00000197530 E072 9.1867641 0.0016122952 0.56781434 0.80551903 1 1629639 1629704 66 + 0.998 0.947 -0.190
ENSG00000197530 E073 19.0861498 0.0007857744 0.16360766 0.43250737 1 1630292 1630605 314 + 1.319 1.227 -0.324

Help

Please Click HERE to learn more details about the results from DEXseq.