ENSG00000197548

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000354449 ENSG00000197548 No_inf pgKDN_inf ATG7 protein_coding protein_coding 49.34711 39.3429 63.47059 6.173448 10.48422 0.6898456 8.480048 10.309598 7.373987 0.9163916 0.7358595 -0.4829148 0.19854167 0.289700 0.124525 -0.165175 2.463181e-01 1.835953e-10 FALSE TRUE
ENST00000424071 ENSG00000197548 No_inf pgKDN_inf ATG7 protein_coding nonsense_mediated_decay 49.34711 39.3429 63.47059 6.173448 10.48422 0.6898456 3.745387 3.517550 5.366599 2.0377874 3.9624350 0.6080274 0.05788333 0.070700 0.064050 -0.006650 9.897267e-01 1.835953e-10 FALSE FALSE
ENST00000427759 ENSG00000197548 No_inf pgKDN_inf ATG7 protein_coding protein_coding 49.34711 39.3429 63.47059 6.173448 10.48422 0.6898456 6.208400 4.579852 8.510311 1.5505971 2.9969274 0.8924586 0.12255833 0.131925 0.140875 0.008950 1.000000e+00 1.835953e-10   FALSE
ENST00000446110 ENSG00000197548 No_inf pgKDN_inf ATG7 protein_coding protein_coding 49.34711 39.3429 63.47059 6.173448 10.48422 0.6898456 5.653839 5.096716 8.501429 2.2406940 3.7382685 0.7370055 0.10530833 0.112725 0.128075 0.015350 1.000000e+00 1.835953e-10 FALSE TRUE
ENST00000451830 ENSG00000197548 No_inf pgKDN_inf ATG7 protein_coding protein_coding 49.34711 39.3429 63.47059 6.173448 10.48422 0.6898456 2.892670 1.316335 2.382449 1.3163345 1.7246286 0.8510437 0.05329167 0.024800 0.045700 0.020900 8.477234e-01 1.835953e-10 FALSE FALSE
ENST00000467121 ENSG00000197548 No_inf pgKDN_inf ATG7 protein_coding retained_intron 49.34711 39.3429 63.47059 6.173448 10.48422 0.6898456 5.003728 4.704360 8.622186 3.1255991 4.1229474 0.8726641 0.08420000 0.097450 0.115500 0.018050 8.370945e-01 1.835953e-10 FALSE FALSE
MSTRG.19732.18 ENSG00000197548 No_inf pgKDN_inf ATG7 protein_coding   49.34711 39.3429 63.47059 6.173448 10.48422 0.6898456 4.693426 0.000000 8.299472 0.0000000 0.8053512 9.6986129 0.09533333 0.000000 0.135925 0.135925 1.835953e-10 1.835953e-10 FALSE TRUE
MSTRG.19732.4 ENSG00000197548 No_inf pgKDN_inf ATG7 protein_coding   49.34711 39.3429 63.47059 6.173448 10.48422 0.6898456 4.909381 2.718723 4.700276 1.0510640 0.3022077 0.7875857 0.10926667 0.073275 0.081975 0.008700 8.556445e-01 1.835953e-10 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000197548 E001 0.0000000       3 11272309 11272347 39 +      
ENSG00000197548 E002 0.1187032 0.0118607424 6.266560e-01   3 11272348 11272371 24 + 0.089 0.000 -11.008
ENSG00000197548 E003 0.2373413 0.0157328984 2.997250e-01   3 11272372 11272374 3 + 0.162 0.000 -14.057
ENSG00000197548 E004 0.2373413 0.0157328984 2.997250e-01   3 11272375 11272381 7 + 0.162 0.000 -14.057
ENSG00000197548 E005 0.7173147 0.0146505040 1.338521e-01 0.388770806 3 11272382 11272396 15 + 0.329 0.102 -2.101
ENSG00000197548 E006 0.9513227 0.1109593442 6.592271e-02 0.258580029 3 11272397 11272402 6 + 0.413 0.102 -2.585
ENSG00000197548 E007 0.9513227 0.1109593442 6.592271e-02 0.258580029 3 11272403 11272405 3 + 0.413 0.102 -2.585
ENSG00000197548 E008 3.1451395 0.0089745598 2.443852e-01 0.534582686 3 11272406 11272415 10 + 0.686 0.529 -0.696
ENSG00000197548 E009 3.7617497 0.0052825327 4.108283e-01 0.692615577 3 11272416 11272422 7 + 0.725 0.620 -0.442
ENSG00000197548 E010 4.2432286 0.0067563924 2.924223e-01 0.585952721 3 11272423 11272430 8 + 0.777 0.647 -0.538
ENSG00000197548 E011 0.0000000       3 11272431 11272442 12 +      
ENSG00000197548 E012 0.2441403 0.0161670661 9.041599e-01   3 11272443 11272709 267 + 0.089 0.102 0.221
ENSG00000197548 E013 0.1272623 0.0123902942 4.607075e-01   3 11274244 11274273 30 + 0.000 0.102 12.959
ENSG00000197548 E014 0.2363338 0.0156301321 2.999846e-01   3 11277219 11277419 201 + 0.162 0.000 -14.057
ENSG00000197548 E015 0.8631399 0.0128864160 5.630628e-01 0.802606634 3 11280994 11281036 43 + 0.225 0.313 0.636
ENSG00000197548 E016 1.2276825 0.0262187579 8.112025e-01 0.930524525 3 11281037 11281102 66 + 0.329 0.366 0.221
ENSG00000197548 E017 0.7358776 0.0134859734 8.504497e-01 0.946982055 3 11282193 11282211 19 + 0.225 0.254 0.221
ENSG00000197548 E018 1.4814519 0.0327602510 4.179690e-01 0.697690608 3 11282212 11282274 63 + 0.329 0.455 0.707
ENSG00000197548 E019 2.9398947 0.0048311412 7.066590e-01 0.881020435 3 11282275 11282438 164 + 0.571 0.620 0.221
ENSG00000197548 E020 0.3726934 0.0165487303 4.923681e-01   3 11288646 11288648 3 + 0.089 0.184 1.221
ENSG00000197548 E021 0.5082629 0.2138516479 5.701484e-02 0.238652551 3 11288649 11288740 92 + 0.000 0.313 14.534
ENSG00000197548 E022 21.4115236 0.0070283812 2.619827e-01 0.554713342 3 11298686 11298855 170 + 1.386 1.307 -0.275
ENSG00000197548 E023 0.2533610 0.0159607989 1.940253e-01   3 11298856 11299170 315 + 0.000 0.184 13.908
ENSG00000197548 E024 12.4095638 0.0013955764 3.150746e-01 0.607899843 3 11299362 11299416 55 + 1.164 1.083 -0.293
ENSG00000197548 E025 0.7339611 0.0134609113 8.508371e-01 0.947214621 3 11304504 11304667 164 + 0.225 0.254 0.221
ENSG00000197548 E026 19.8000470 0.0007062357 7.192364e-01 0.886807486 3 11306943 11307060 118 + 1.307 1.329 0.079
ENSG00000197548 E027 0.0000000       3 11308442 11308474 33 +      
ENSG00000197548 E028 0.0000000       3 11308475 11308612 138 +      
ENSG00000197548 E029 0.3809057 0.0159088550 7.651784e-02   3 11308613 11308861 249 + 0.000 0.254 14.457
ENSG00000197548 E030 9.9736481 0.0014445303 3.968587e-01 0.681336205 3 11308984 11309008 25 + 1.075 0.999 -0.276
ENSG00000197548 E031 13.3897421 0.0011735639 3.631833e-01 0.652179395 3 11309009 11309061 53 + 1.191 1.119 -0.255
ENSG00000197548 E032 7.4453952 0.0334289251 8.127170e-01 0.931205697 3 11313304 11313342 39 + 0.940 0.910 -0.112
ENSG00000197548 E033 13.7156654 0.0010902355 8.331075e-02 0.297474349 3 11313343 11313420 78 + 1.227 1.092 -0.482
ENSG00000197548 E034 21.7238235 0.0010072072 2.794849e-02 0.156156021 3 11315344 11315493 150 + 1.418 1.278 -0.486
ENSG00000197548 E035 14.6052353 0.0009487466 3.248199e-01 0.617229842 3 11331340 11331401 62 + 1.227 1.153 -0.264
ENSG00000197548 E036 9.6379867 0.0014230234 9.212172e-01 0.975438365 3 11331402 11331428 27 + 1.031 1.022 -0.035
ENSG00000197548 E037 0.2539903 0.0160190703 1.939160e-01   3 11331429 11331440 12 + 0.000 0.184 13.908
ENSG00000197548 E038 0.2352613 0.2092297475 3.501083e-01   3 11332713 11332971 259 + 0.162 0.000 -13.939
ENSG00000197548 E039 16.7450223 0.0008046386 7.565658e-01 0.904164728 3 11332972 11333093 122 + 1.239 1.260 0.074
ENSG00000197548 E040 17.5420385 0.0027002943 4.731032e-01 0.740162011 3 11340645 11340735 91 + 1.292 1.240 -0.182
ENSG00000197548 E041 15.9888647 0.0009896706 9.414675e-01 0.983537798 3 11342135 11342199 65 + 1.233 1.227 -0.021
ENSG00000197548 E042 22.2135143 0.0172848558 9.177997e-01 0.974114604 3 11342200 11342279 80 + 1.366 1.365 -0.001
ENSG00000197548 E043 0.2356421 0.0156765526 2.997985e-01   3 11346526 11346565 40 + 0.162 0.000 -14.056
ENSG00000197548 E044 35.4412428 0.0004766550 2.685249e-01 0.562039110 3 11347877 11348035 159 + 1.587 1.532 -0.188
ENSG00000197548 E045 3.9632215 0.0034519137 2.800145e-02 0.156322361 3 11348036 11348747 712 + 0.543 0.816 1.154
ENSG00000197548 E046 42.8677210 0.0004039611 9.931265e-01 1.000000000 3 11358418 11358612 195 + 1.642 1.642 -0.001
ENSG00000197548 E047 40.3886292 0.0005263826 2.709294e-01 0.564630390 3 11360581 11360784 204 + 1.592 1.642 0.169
ENSG00000197548 E048 30.9984157 0.0018875962 7.018171e-01 0.878680611 3 11362813 11362928 116 + 1.515 1.493 -0.075
ENSG00000197548 E049 0.2346346 0.0155734751 3.000565e-01   3 11362929 11363096 168 + 0.162 0.000 -14.056
ENSG00000197548 E050 0.0000000       3 11364657 11364657 1 +      
ENSG00000197548 E051 0.0000000       3 11364658 11364658 1 +      
ENSG00000197548 E052 25.5278415 0.0005605917 9.539431e-01 0.988661943 3 11364659 11364734 76 + 1.425 1.421 -0.014
ENSG00000197548 E053 28.5057919 0.0005219842 4.631964e-01 0.733201974 3 11379972 11380052 81 + 1.450 1.489 0.135
ENSG00000197548 E054 33.3505596 0.0003938139 5.459721e-02 0.232796256 3 11426804 11426926 123 + 1.487 1.583 0.328
ENSG00000197548 E055 1.9667784 0.0075215750 4.242228e-01 0.703416570 3 11446509 11446936 428 + 0.413 0.529 0.584
ENSG00000197548 E056 11.6207189 0.0012482559 6.546022e-01 0.855024940 3 11467398 11468503 1106 + 1.083 1.119 0.130
ENSG00000197548 E057 2.1913355 0.0109375880 8.908150e-01 0.963657304 3 11477134 11477307 174 + 0.514 0.493 -0.100
ENSG00000197548 E058 1.8337106 0.1132558947 9.684196e-01 0.993641226 3 11510185 11510339 155 + 0.449 0.455 0.028
ENSG00000197548 E059 41.9560506 0.0003750498 7.216395e-05 0.001803564 3 11554811 11557665 2855 + 1.538 1.716 0.604

Help

Please Click HERE to learn more details about the results from DEXseq.