ENSG00000197586

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000360031 ENSG00000197586 No_inf pgKDN_inf ENTPD6 protein_coding protein_coding 47.64171 33.67021 53.2312 1.807204 3.109368 0.6606421 6.3524796 5.4729116 6.702979 2.2392801 0.9075774 0.2920110 0.13670000 0.163875 0.125700 -0.038175 1.00000000 0.01900113 FALSE TRUE
ENST00000376652 ENSG00000197586 No_inf pgKDN_inf ENTPD6 protein_coding protein_coding 47.64171 33.67021 53.2312 1.807204 3.109368 0.6606421 8.5051065 4.4067153 13.249135 1.7636382 1.6594568 1.5859409 0.17466667 0.133925 0.246750 0.112825 0.61274069 0.01900113 FALSE TRUE
ENST00000425813 ENSG00000197586 No_inf pgKDN_inf ENTPD6 protein_coding protein_coding 47.64171 33.67021 53.2312 1.807204 3.109368 0.6606421 2.4340780 1.8929555 0.000000 0.8418129 0.0000000 -7.5720980 0.04949167 0.054150 0.000000 -0.054150 0.03584797 0.01900113 FALSE TRUE
ENST00000433259 ENSG00000197586 No_inf pgKDN_inf ENTPD6 protein_coding protein_coding 47.64171 33.67021 53.2312 1.807204 3.109368 0.6606421 4.1670054 0.5764125 5.616902 0.5764125 1.9836454 3.2623530 0.08056667 0.015675 0.112725 0.097050 0.33246649 0.01900113 FALSE TRUE
ENST00000433417 ENSG00000197586 No_inf pgKDN_inf ENTPD6 protein_coding protein_coding 47.64171 33.67021 53.2312 1.807204 3.109368 0.6606421 6.4267397 3.8907498 4.789360 2.3725430 2.9964147 0.2990904 0.12808333 0.107675 0.092525 -0.015150 1.00000000 0.01900113 FALSE FALSE
ENST00000439162 ENSG00000197586 No_inf pgKDN_inf ENTPD6 protein_coding protein_coding 47.64171 33.67021 53.2312 1.807204 3.109368 0.6606421 4.1036529 2.2292379 6.431138 1.3837504 2.4642557 1.5243079 0.08630833 0.071925 0.117900 0.045975 0.81640979 0.01900113 FALSE FALSE
ENST00000447877 ENSG00000197586 No_inf pgKDN_inf ENTPD6 protein_coding protein_coding 47.64171 33.67021 53.2312 1.807204 3.109368 0.6606421 5.7093004 2.7737182 9.316137 1.7537519 5.5850332 1.7442665 0.11385833 0.080200 0.169150 0.088950 1.00000000 0.01900113 FALSE FALSE
ENST00000485936 ENSG00000197586 No_inf pgKDN_inf ENTPD6 protein_coding protein_coding_CDS_not_defined 47.64171 33.67021 53.2312 1.807204 3.109368 0.6606421 3.9684722 5.4548475 2.261713 0.3059835 0.5949898 -1.2664004 0.09434167 0.163200 0.044400 -0.118800 0.04784606 0.01900113 TRUE TRUE
MSTRG.18092.14 ENSG00000197586 No_inf pgKDN_inf ENTPD6 protein_coding   47.64171 33.67021 53.2312 1.807204 3.109368 0.6606421 0.8052122 2.4156366 0.000000 0.8210429 0.0000000 -7.9222196 0.02451667 0.073550 0.000000 -0.073550 0.01900113 0.01900113 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000197586 E001 0.2373413 0.0157111979 4.026963e-01   20 25195693 25195700 8 + 0.147 0.000 -9.767
ENSG00000197586 E002 0.2373413 0.0157111979 4.026963e-01   20 25195701 25195701 1 + 0.147 0.000 -12.122
ENSG00000197586 E003 0.3560444 0.0354961131 2.034808e-01   20 25195702 25195711 10 + 0.206 0.000 -12.552
ENSG00000197586 E004 1.4559912 0.0571924507 6.338368e-01 8.434788e-01 20 25195712 25195725 14 + 0.418 0.340 -0.445
ENSG00000197586 E005 1.4559912 0.0571924507 6.338368e-01 8.434788e-01 20 25195726 25195729 4 + 0.418 0.340 -0.445
ENSG00000197586 E006 1.5828452 0.0534007394 8.866475e-01 9.621239e-01 20 25195730 25195734 5 + 0.418 0.395 -0.123
ENSG00000197586 E007 1.6998492 0.0117595058 7.109825e-01 8.831851e-01 20 25195735 25195735 1 + 0.450 0.395 -0.293
ENSG00000197586 E008 5.6081883 0.0025376949 6.964539e-01 8.760534e-01 20 25195736 25195756 21 + 0.796 0.841 0.177
ENSG00000197586 E009 7.4199742 0.0020734336 9.539778e-01 9.886732e-01 20 25195757 25195774 18 + 0.917 0.925 0.030
ENSG00000197586 E010 8.5105105 0.0016758300 9.160236e-01 9.737050e-01 20 25195775 25195791 17 + 0.977 0.969 -0.029
ENSG00000197586 E011 8.0284023 0.0017640365 9.623848e-01 9.918351e-01 20 25195792 25195792 1 + 0.948 0.955 0.025
ENSG00000197586 E012 11.3966224 0.0012172230 3.795055e-01 6.662160e-01 20 25195793 25195838 46 + 1.118 1.045 -0.264
ENSG00000197586 E013 8.7217240 0.0016783573 3.079801e-01 6.012775e-01 20 25195839 25195867 29 + 1.021 0.925 -0.355
ENSG00000197586 E014 1.3450308 0.0104813160 7.486582e-01 9.007748e-01 20 25196154 25196254 101 + 0.345 0.395 0.292
ENSG00000197586 E015 0.3731018 0.0164944626 3.753091e-01   20 25197105 25197201 97 + 0.080 0.202 1.556
ENSG00000197586 E016 0.1271363 0.0122737743 3.637159e-01   20 25197202 25197226 25 + 0.000 0.113 11.092
ENSG00000197586 E017 14.0766151 0.0198274129 6.633263e-01 8.597841e-01 20 25206522 25206590 69 + 1.191 1.148 -0.155
ENSG00000197586 E018 5.0700546 0.0036023454 2.021661e-01 4.846130e-01 20 25207076 25207078 3 + 0.836 0.686 -0.602
ENSG00000197586 E019 44.6222454 0.0004065348 9.472042e-02 3.202244e-01 20 25207079 25207343 265 + 1.683 1.610 -0.249
ENSG00000197586 E020 22.2321668 0.0006289954 1.651590e-02 1.119197e-01 20 25207344 25207397 54 + 1.419 1.267 -0.528
ENSG00000197586 E021 26.5116052 0.0005391750 7.128599e-02 2.705467e-01 20 25209849 25209925 77 + 1.475 1.372 -0.356
ENSG00000197586 E022 26.7568714 0.0059582473 9.381345e-01 9.821929e-01 20 25213263 25213339 77 + 1.439 1.438 -0.002
ENSG00000197586 E023 20.8551261 0.0086286298 3.428538e-01 6.342472e-01 20 25213340 25213406 67 + 1.362 1.294 -0.235
ENSG00000197586 E024 21.7662567 0.0051585695 9.000903e-02 3.116284e-01 20 25214867 25214942 76 + 1.398 1.281 -0.408
ENSG00000197586 E025 18.3062944 0.0101541428 4.522254e-01 7.254275e-01 20 25215676 25215697 22 + 1.305 1.246 -0.207
ENSG00000197586 E026 13.4211837 0.0013039085 7.786428e-02 2.854688e-01 20 25215698 25215711 14 + 1.208 1.068 -0.503
ENSG00000197586 E027 27.4865156 0.0005265192 5.190932e-02 2.262000e-01 20 25216648 25216736 89 + 1.493 1.383 -0.378
ENSG00000197586 E028 27.6415249 0.0154114725 2.877647e-01 5.812713e-01 20 25217502 25217581 80 + 1.484 1.404 -0.277
ENSG00000197586 E029 22.7440487 0.0014099509 4.766764e-02 2.147254e-01 20 25218550 25218614 65 + 1.419 1.294 -0.433
ENSG00000197586 E030 21.6748304 0.0071815206 6.101398e-01 8.305161e-01 20 25221232 25221333 102 + 1.334 1.372 0.131
ENSG00000197586 E031 8.9307238 0.0475784066 9.780562e-04 1.475951e-02 20 25221792 25222058 267 + 0.767 1.183 1.555
ENSG00000197586 E032 10.3915752 0.0047880471 3.016229e-12 3.714093e-10 20 25222059 25222426 368 + 0.647 1.314 2.512
ENSG00000197586 E033 10.3546905 0.0034718307 8.420537e-10 7.300093e-08 20 25222427 25222837 411 + 0.719 1.288 2.117
ENSG00000197586 E034 36.7480858 0.0004263872 1.515708e-01 4.149232e-01 20 25222838 25222978 141 + 1.599 1.531 -0.235
ENSG00000197586 E035 1.3869845 0.0524355969 1.002010e-03 1.503266e-02 20 25223867 25224100 234 + 0.080 0.598 3.877
ENSG00000197586 E036 31.0062894 0.0005380915 9.416553e-01 9.835583e-01 20 25224101 25224157 57 + 1.501 1.499 -0.006
ENSG00000197586 E037 5.7900826 0.0073013696 1.152849e-02 8.834574e-02 20 25224158 25224630 473 + 0.684 0.969 1.115
ENSG00000197586 E038 5.4386545 0.0064632311 7.176800e-03 6.410625e-02 20 25224631 25225161 531 + 0.647 0.955 1.223
ENSG00000197586 E039 8.4596236 0.0016645354 9.306630e-02 3.169437e-01 20 25225162 25225204 43 + 0.896 1.056 0.597
ENSG00000197586 E040 39.8879586 0.0003947450 9.804820e-01 9.978172e-01 20 25225205 25225317 113 + 1.606 1.607 0.004
ENSG00000197586 E041 236.8580019 0.0001338950 7.211187e-02 2.723213e-01 20 25225499 25228075 2577 + 2.357 2.390 0.108

Help

Please Click HERE to learn more details about the results from DEXseq.