ENSG00000197622

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000357235 ENSG00000197622 No_inf pgKDN_inf CDC42SE1 protein_coding protein_coding 164.8022 118.3664 185.1391 3.318194 2.024419 0.6453059 122.20120 79.657651 146.100938 3.116841 1.7682681 0.8749982 0.73320000 0.672450 0.789350 0.116900 0.0009627006 0.0009627006   FALSE
ENST00000483763 ENSG00000197622 No_inf pgKDN_inf CDC42SE1 protein_coding retained_intron 164.8022 118.3664 185.1391 3.318194 2.024419 0.6453059 17.13230 13.334325 16.707314 2.159178 0.2789073 0.3251168 0.10470000 0.111925 0.090250 -0.021675 0.8345017664 0.0009627006 TRUE FALSE
MSTRG.1842.3 ENSG00000197622 No_inf pgKDN_inf CDC42SE1 protein_coding   164.8022 118.3664 185.1391 3.318194 2.024419 0.6453059 13.26357 16.516001 9.014472 1.157561 0.8299833 -0.8728232 0.08805833 0.140650 0.048800 -0.091850 0.0022346934 0.0009627006 TRUE FALSE
MSTRG.1842.7 ENSG00000197622 No_inf pgKDN_inf CDC42SE1 protein_coding   164.8022 118.3664 185.1391 3.318194 2.024419 0.6453059 10.20097 6.687417 10.967310 2.283397 2.0315591 0.7128478 0.06066667 0.055250 0.058925 0.003675 0.8984952151 0.0009627006   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000197622 E001 0.0000000       1 151050971 151050972 2 -      
ENSG00000197622 E002 0.0000000       1 151050973 151050984 12 -      
ENSG00000197622 E003 458.1183772 1.210747e-04 5.782755e-02 2.406536e-01 1 151050985 151052113 1129 - 2.646 2.676 0.099
ENSG00000197622 E004 741.0935591 4.953010e-05 8.435894e-03 7.169580e-02 1 151052114 151052945 832 - 2.878 2.857 -0.070
ENSG00000197622 E005 317.0424849 7.508722e-05 1.161180e-05 3.892298e-04 1 151052946 151053327 382 - 2.529 2.462 -0.226
ENSG00000197622 E006 55.0699097 2.625506e-04 9.761675e-01 9.960011e-01 1 151054231 151054236 6 - 1.745 1.748 0.010
ENSG00000197622 E007 118.3164453 1.346372e-04 3.206221e-01 6.135333e-01 1 151054237 151054321 85 - 2.085 2.062 -0.078
ENSG00000197622 E008 123.1360893 3.326245e-03 4.657323e-12 5.569581e-10 1 151054322 151055015 694 - 1.961 2.211 0.838
ENSG00000197622 E009 145.3293441 4.157825e-04 1.564446e-04 3.411963e-03 1 151055016 151055126 111 - 2.203 2.109 -0.315
ENSG00000197622 E010 112.0900828 1.660850e-04 1.025616e-26 4.768584e-24 1 151055127 151055582 456 - 1.884 2.195 1.042
ENSG00000197622 E011 25.4285096 5.306231e-04 4.010235e-07 2.029905e-05 1 151055583 151055676 94 - 1.257 1.561 1.051
ENSG00000197622 E012 210.6437535 9.150465e-05 1.948295e-13 2.772542e-11 1 151055677 151055993 317 - 2.384 2.235 -0.496
ENSG00000197622 E013 16.4349233 5.821473e-03 5.926027e-02 2.443386e-01 1 151055994 151056650 657 - 1.166 1.315 0.525
ENSG00000197622 E014 3.7874308 4.729651e-02 6.300230e-01 8.413306e-01 1 151056651 151056655 5 - 0.645 0.717 0.303
ENSG00000197622 E015 12.8950892 1.688356e-03 2.852407e-02 1.581059e-01 1 151056656 151056786 131 - 1.051 1.230 0.643
ENSG00000197622 E016 15.6271630 1.119589e-02 5.867412e-06 2.154366e-04 1 151056787 151057295 509 - 0.998 1.391 1.395
ENSG00000197622 E017 51.6808706 3.113783e-04 8.079146e-03 6.957379e-02 1 151059479 151059773 295 - 1.765 1.657 -0.367
ENSG00000197622 E018 0.0000000       1 151067132 151067334 203 -      
ENSG00000197622 E019 0.0000000       1 151068319 151068380 62 -      
ENSG00000197622 E020 0.3711203 1.651315e-02 4.326852e-01   1 151070264 151070325 62 - 0.084 0.194 1.393

Help

Please Click HERE to learn more details about the results from DEXseq.