ENSG00000197818

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000361573 ENSG00000197818 No_inf pgKDN_inf SLC9A8 protein_coding protein_coding 7.759221 6.598819 7.633219 0.2501577 0.49925 0.2097878 4.102464 1.8798016 5.4920954 0.8997360 0.9660826 1.5417463 0.5274500 0.291500 0.74945 0.457950 0.35495010 0.02091583 FALSE TRUE
ENST00000417961 ENSG00000197818 No_inf pgKDN_inf SLC9A8 protein_coding protein_coding 7.759221 6.598819 7.633219 0.2501577 0.49925 0.2097878 1.162667 0.9089073 1.4979207 0.9089073 0.9422922 0.7145693 0.1472667 0.144425 0.17590 0.031475 0.82736423 0.02091583 FALSE TRUE
ENST00000490250 ENSG00000197818 No_inf pgKDN_inf SLC9A8 protein_coding protein_coding_CDS_not_defined 7.759221 6.598819 7.633219 0.2501577 0.49925 0.2097878 1.162830 2.1683813 0.2666363 0.1799525 0.2666363 -2.9771944 0.1587667 0.329900 0.03045 -0.299450 0.02091583 0.02091583   FALSE
MSTRG.18386.3 ENSG00000197818 No_inf pgKDN_inf SLC9A8 protein_coding   7.759221 6.598819 7.633219 0.2501577 0.49925 0.2097878 1.205739 1.6417291 0.0000000 0.9571864 0.0000000 -7.3678333 0.1517667 0.234150 0.00000 -0.234150 0.47422181 0.02091583 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000197818 E001 0.3621152 0.158193770 0.6840005588   20 49812713 49812827 115 + 0.161 0.103 -0.754
ENSG00000197818 E002 0.7262454 0.284155064 0.5571966608 0.7992522295 20 49812828 49812892 65 + 0.279 0.186 -0.755
ENSG00000197818 E003 0.4817608 0.036281167 0.3767085896   20 49812893 49812893 1 + 0.224 0.103 -1.340
ENSG00000197818 E004 1.7148574 0.008233762 0.8471744467 0.9457833993 20 49812894 49812948 55 + 0.411 0.457 0.245
ENSG00000197818 E005 5.6398110 0.030173785 0.7393924936 0.8967545124 20 49815008 49815189 182 + 0.790 0.853 0.245
ENSG00000197818 E006 0.0000000       20 49815190 49815444 255 +      
ENSG00000197818 E007 2.0951391 0.007330689 0.3500743975 0.6402696787 20 49823061 49823072 12 + 0.411 0.564 0.760
ENSG00000197818 E008 4.4824942 0.004006174 0.1346063444 0.3901052434 20 49823073 49823141 69 + 0.806 0.650 -0.639
ENSG00000197818 E009 5.2029819 0.003902725 0.0504989496 0.2220738977 20 49839541 49839599 59 + 0.876 0.675 -0.805
ENSG00000197818 E010 5.2163903 0.002842029 0.1801735895 0.4556208917 20 49845036 49845119 84 + 0.849 0.721 -0.510
ENSG00000197818 E011 5.1857670 0.016192679 0.0318745614 0.1687126606 20 49849579 49849680 102 + 0.889 0.650 -0.961
ENSG00000197818 E012 0.8426856 0.023146873 0.3170087466 0.6097235712 20 49850762 49850809 48 + 0.327 0.186 -1.077
ENSG00000197818 E013 2.7575981 0.005441091 0.0114815629 0.0880696520 20 49850810 49850844 35 + 0.703 0.368 -1.603
ENSG00000197818 E014 5.2695372 0.002577554 0.0002090293 0.0043391764 20 49855438 49855581 144 + 0.948 0.531 -1.714
ENSG00000197818 E015 1.0718783 0.011156942 0.0206796194 0.1295594207 20 49862929 49862933 5 + 0.447 0.103 -2.755
ENSG00000197818 E016 4.7335824 0.003076369 0.2630569425 0.5559448722 20 49862934 49863067 134 + 0.806 0.699 -0.433
ENSG00000197818 E017 3.4037826 0.023095857 0.4225562433 0.7018797698 20 49864739 49864844 106 + 0.683 0.595 -0.383
ENSG00000197818 E018 5.8821717 0.077094215 0.7794654652 0.9150053868 20 49874705 49874821 117 + 0.806 0.869 0.245
ENSG00000197818 E019 5.5110930 0.077974282 0.9133180709 0.9725157812 20 49877981 49878063 83 + 0.791 0.836 0.180
ENSG00000197818 E020 6.6914245 0.076648625 0.4370568783 0.7134666810 20 49880924 49881035 112 + 0.925 0.836 -0.341
ENSG00000197818 E021 10.9942038 0.002283747 0.9395064521 0.9827836263 20 49883846 49884066 221 + 1.063 1.095 0.117
ENSG00000197818 E022 2.6478693 0.005793452 0.0000295855 0.0008565027 20 49886371 49886751 381 + 0.161 0.783 3.493
ENSG00000197818 E023 8.5943823 0.001614675 0.2464107548 0.5370603348 20 49886752 49886898 147 + 0.914 1.046 0.493
ENSG00000197818 E024 159.0955414 0.008451528 0.0136826294 0.0985522081 20 49887829 49892242 4414 + 2.165 2.243 0.261

Help

Please Click HERE to learn more details about the results from DEXseq.