ENSG00000197872

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000381323 ENSG00000197872 No_inf pgKDN_inf CYRIA protein_coding protein_coding 12.62016 4.428874 17.02888 0.1511442 1.155771 1.940565 8.442695 4.132736 11.105690 0.05674196 0.2751989 1.423942 0.75443333 0.9367 0.660375 -0.276325 0.02228713 0.01281794 FALSE TRUE
ENST00000406434 ENSG00000197872 No_inf pgKDN_inf CYRIA protein_coding protein_coding 12.62016 4.428874 17.02888 0.1511442 1.155771 1.940565 1.196168 0.000000 2.513689 0.00000000 0.2907151 7.979390 0.07355833 0.0000 0.151275 0.151275 0.01281794 0.01281794 FALSE TRUE
ENST00000445605 ENSG00000197872 No_inf pgKDN_inf CYRIA protein_coding protein_coding 12.62016 4.428874 17.02888 0.1511442 1.155771 1.940565 1.474610 0.000000 0.000000 0.00000000 0.0000000 0.000000 0.07060000 0.0000 0.000000 0.000000   0.01281794   FALSE
ENST00000451689 ENSG00000197872 No_inf pgKDN_inf CYRIA protein_coding protein_coding 12.62016 4.428874 17.02888 0.1511442 1.155771 1.940565 1.001803 0.000000 2.653797 0.00000000 1.2432230 8.057340 0.05890000 0.0000 0.146200 0.146200 0.22894229 0.01281794   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000197872 E001 119.7063389 0.0001963795 6.775970e-19 1.661160e-16 2 16549459 16552935 3477 - 1.980 2.147 0.562
ENSG00000197872 E002 8.3243857 0.0015989132 8.795737e-04 1.360061e-02 2 16552936 16552999 64 - 1.005 0.591 -1.656
ENSG00000197872 E003 8.9210019 0.0015586605 1.033486e-03 1.536360e-02 2 16555069 16555139 71 - 1.030 0.634 -1.552
ENSG00000197872 E004 10.3830507 0.0059654820 3.512931e-02 1.794190e-01 2 16559460 16559586 127 - 1.063 0.832 -0.869
ENSG00000197872 E005 0.8521899 0.0137049404 3.276419e-01 6.202105e-01 2 16560657 16560989 333 - 0.198 0.350 1.099
ENSG00000197872 E006 5.9652939 0.0038886047 1.005572e-01 3.311057e-01 2 16560990 16561069 80 - 0.850 0.634 -0.878
ENSG00000197872 E007 8.9970516 0.0016957642 5.418798e-01 7.893578e-01 2 16561161 16561277 117 - 0.973 0.905 -0.257
ENSG00000197872 E008 9.2417769 0.0015863290 4.581403e-01 7.300736e-01 2 16561456 16561533 78 - 0.986 0.905 -0.306
ENSG00000197872 E009 10.4058788 0.0334903221 7.278796e-02 2.740869e-01 2 16562005 16562141 137 - 1.064 0.832 -0.870
ENSG00000197872 E010 3.3366860 0.0093384276 5.110103e-02 2.238061e-01 2 16563989 16564004 16 - 0.665 0.350 -1.545
ENSG00000197872 E011 3.8081003 0.0043139385 2.004580e-02 1.271343e-01 2 16564005 16564023 19 - 0.716 0.350 -1.759
ENSG00000197872 E012 6.5447266 0.0221006583 3.988528e-03 4.235426e-02 2 16564024 16564094 71 - 0.916 0.487 -1.809
ENSG00000197872 E013 8.8343473 0.0016474354 2.312505e-02 1.387007e-01 2 16565646 16565767 122 - 1.005 0.744 -1.004
ENSG00000197872 E014 6.7281428 0.0021189469 6.700615e-01 8.629935e-01 2 16588050 16588129 80 - 0.859 0.805 -0.212
ENSG00000197872 E015 0.4703418 0.0160657636 3.396968e-01   2 16622939 16623137 199 - 0.198 0.000 -10.394
ENSG00000197872 E016 8.8703743 0.0016134268 2.709489e-01 5.646365e-01 2 16623864 16624019 156 - 0.980 0.858 -0.462
ENSG00000197872 E017 0.1186381 0.0118346774 1.000000e+00   2 16625728 16625769 42 - 0.059 0.000 -8.497
ENSG00000197872 E018 2.5034137 0.0055886706 2.059090e-01 4.894014e-01 2 16665780 16665841 62 - 0.557 0.350 -1.071
ENSG00000197872 E019 0.0000000       2 16665991 16666086 96 -      
ENSG00000197872 E020 0.0000000       2 16666224 16666331 108 -      

Help

Please Click HERE to learn more details about the results from DEXseq.