ENSG00000197885

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000412028 ENSG00000197885 No_inf pgKDN_inf NKIRAS1 protein_coding protein_coding 4.360507 3.540272 4.520723 0.3805421 0.3287479 0.3518117 0.3075764 0.1018566 0.8208726 0.1018566 0.82087264 2.892977 0.07241667 0.037650 0.179600 0.141950 1.00000000 0.02672045 FALSE TRUE
ENST00000416026 ENSG00000197885 No_inf pgKDN_inf NKIRAS1 protein_coding protein_coding 4.360507 3.540272 4.520723 0.3805421 0.3287479 0.3518117 0.8396845 0.0000000 0.3917817 0.0000000 0.39178173 5.328340 0.15470000 0.000000 0.073000 0.073000 0.84979417 0.02672045 FALSE TRUE
ENST00000425478 ENSG00000197885 No_inf pgKDN_inf NKIRAS1 protein_coding protein_coding 4.360507 3.540272 4.520723 0.3805421 0.3287479 0.3518117 2.0818788 3.0151405 1.4864371 0.2771301 0.07674381 -1.015470 0.52060000 0.869375 0.334400 -0.534975 0.02672045 0.02672045 FALSE TRUE
ENST00000614374 ENSG00000197885 No_inf pgKDN_inf NKIRAS1 protein_coding protein_coding 4.360507 3.540272 4.520723 0.3805421 0.3287479 0.3518117 0.5927181 0.0000000 1.7781543 0.0000000 0.59558645 7.482327 0.13434167 0.000000 0.403025 0.403025 0.05422691 0.02672045 FALSE TRUE
MSTRG.19831.7 ENSG00000197885 No_inf pgKDN_inf NKIRAS1 protein_coding   4.360507 3.540272 4.520723 0.3805421 0.3287479 0.3518117 0.1993950 0.4232746 0.0000000 0.4232746 0.00000000 -5.437210 0.04096667 0.092975 0.000000 -0.092975 0.83139082 0.02672045   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000197885 E001 12.0618809 0.001484440 0.0003320561 0.00631492 3 23889951 23891659 1709 - 0.936 1.209 0.994
ENSG00000197885 E002 1.2409004 0.010879958 0.3416390601 0.63309983 3 23891660 23892060 401 - 0.259 0.405 0.915
ENSG00000197885 E003 0.2438580 0.016753293 0.8687303906   3 23892061 23892063 3 - 0.105 0.086 -0.307
ENSG00000197885 E004 0.2438580 0.016753293 0.8687303906   3 23892064 23892082 19 - 0.105 0.086 -0.307
ENSG00000197885 E005 0.2438580 0.016753293 0.8687303906   3 23892083 23892096 14 - 0.105 0.086 -0.307
ENSG00000197885 E006 0.3611417 0.017396441 0.4589641084   3 23892097 23892147 51 - 0.189 0.086 -1.307
ENSG00000197885 E007 2.3200111 0.012908051 0.4806334873 0.74596235 3 23892148 23892306 159 - 0.571 0.474 -0.460
ENSG00000197885 E008 0.8789076 0.014074907 0.0887492833 0.30909303 3 23892307 23892309 3 - 0.105 0.366 2.277
ENSG00000197885 E009 16.7836064 0.001051482 0.1558123133 0.42185369 3 23892310 23893064 755 - 1.290 1.209 -0.286
ENSG00000197885 E010 7.7304173 0.074878667 0.7141614173 0.88487425 3 23893065 23893333 269 - 0.962 0.917 -0.169
ENSG00000197885 E011 0.4814165 0.017602375 0.2267214383   3 23893334 23893337 4 - 0.259 0.086 -1.892
ENSG00000197885 E012 0.0000000       3 23898340 23898362 23 -      
ENSG00000197885 E013 0.1271363 0.012505422 0.6593678511   3 23900804 23900807 4 - 0.000 0.086 10.991
ENSG00000197885 E014 3.0336768 0.005258410 0.0483025818 0.21630284 3 23900808 23901049 242 - 0.729 0.474 -1.138
ENSG00000197885 E015 2.4236093 0.006211656 0.0649009114 0.25670836 3 23910811 23910921 111 - 0.657 0.405 -1.201
ENSG00000197885 E016 0.0000000       3 23910922 23910925 4 -      
ENSG00000197885 E017 2.1068382 0.008233215 0.4317474347 0.70934577 3 23911329 23911446 118 - 0.421 0.534 0.567
ENSG00000197885 E018 0.1271363 0.012505422 0.6593678511   3 23911447 23911450 4 - 0.000 0.086 10.991
ENSG00000197885 E019 0.1176306 0.012114743 0.4349098346   3 23915955 23916783 829 - 0.105 0.000 -11.823
ENSG00000197885 E020 0.1271363 0.012505422 0.6593678511   3 23916784 23916860 77 - 0.000 0.086 10.991
ENSG00000197885 E021 0.0000000       3 23916861 23916990 130 -      
ENSG00000197885 E022 0.0000000       3 23946323 23946591 269 -      

Help

Please Click HERE to learn more details about the results from DEXseq.