ENSG00000197948

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000518499 ENSG00000197948 No_inf pgKDN_inf FCHSD1 protein_coding protein_coding 15.75512 18.58642 13.3052 1.125948 0.7336209 -0.4819504 1.5532570 0.0000000 2.2806399 0.0000000 1.3533451 7.8396069 0.09863333 0.000000 0.167875 0.167875 0.41148589 0.02369064 FALSE FALSE
ENST00000519800 ENSG00000197948 No_inf pgKDN_inf FCHSD1 protein_coding protein_coding 15.75512 18.58642 13.3052 1.125948 0.7336209 -0.4819504 1.3404779 1.7460502 1.4532877 1.0222514 1.0281244 -0.2631206 0.08097500 0.089100 0.110475 0.021375 0.95380140 0.02369064 FALSE TRUE
ENST00000520747 ENSG00000197948 No_inf pgKDN_inf FCHSD1 protein_coding retained_intron 15.75512 18.58642 13.3052 1.125948 0.7336209 -0.4819504 1.1107769 1.7737453 0.6677790 0.2123544 0.1317257 -1.3960227 0.06880833 0.097275 0.049675 -0.047600 0.65386177 0.02369064   FALSE
ENST00000522126 ENSG00000197948 No_inf pgKDN_inf FCHSD1 protein_coding nonsense_mediated_decay 15.75512 18.58642 13.3052 1.125948 0.7336209 -0.4819504 1.2371880 0.5364427 1.9712629 0.5364427 1.1645744 1.8582782 0.08764167 0.033875 0.143250 0.109375 0.74258513 0.02369064 TRUE TRUE
ENST00000522386 ENSG00000197948 No_inf pgKDN_inf FCHSD1 protein_coding protein_coding_CDS_not_defined 15.75512 18.58642 13.3052 1.125948 0.7336209 -0.4819504 1.5894920 3.9237541 0.1942484 1.0823441 0.1942484 -4.2675099 0.09260833 0.208100 0.015525 -0.192575 0.02369064 0.02369064   FALSE
ENST00000522763 ENSG00000197948 No_inf pgKDN_inf FCHSD1 protein_coding protein_coding_CDS_not_defined 15.75512 18.58642 13.3052 1.125948 0.7336209 -0.4819504 0.6181332 0.0000000 0.8661289 0.0000000 0.8661289 6.4530713 0.04021667 0.000000 0.068125 0.068125 0.82900515 0.02369064   FALSE
ENST00000522783 ENSG00000197948 No_inf pgKDN_inf FCHSD1 protein_coding protein_coding 15.75512 18.58642 13.3052 1.125948 0.7336209 -0.4819504 2.0271266 3.6581874 1.3322783 0.5617866 0.7789466 -1.4503835 0.11707500 0.196750 0.095150 -0.101600 0.56446708 0.02369064 TRUE TRUE
ENST00000523856 ENSG00000197948 No_inf pgKDN_inf FCHSD1 protein_coding protein_coding_CDS_not_defined 15.75512 18.58642 13.3052 1.125948 0.7336209 -0.4819504 1.0137066 2.2750127 0.4028093 0.3540999 0.2355139 -2.4686549 0.06107500 0.120800 0.031900 -0.088900 0.23627438 0.02369064 FALSE TRUE
MSTRG.23688.2 ENSG00000197948 No_inf pgKDN_inf FCHSD1 protein_coding   15.75512 18.58642 13.3052 1.125948 0.7336209 -0.4819504 3.4703254 2.2765006 3.7077901 0.8011228 0.3047509 0.7013040 0.23807500 0.128875 0.283725 0.154850 0.54228739 0.02369064 FALSE TRUE
MSTRG.23688.9 ENSG00000197948 No_inf pgKDN_inf FCHSD1 protein_coding   15.75512 18.58642 13.3052 1.125948 0.7336209 -0.4819504 1.1010789 1.6708202 0.4289796 0.3159668 0.4289796 -1.9369396 0.06635000 0.091200 0.034250 -0.056950 0.37979839 0.02369064 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000197948 E001 0.8620409 0.0677135214 0.881816094 0.96028165 5 141639302 141639302 1 - 0.278 0.256 -0.156
ENSG00000197948 E002 0.8620409 0.0677135214 0.881816094 0.96028165 5 141639303 141639307 5 - 0.278 0.256 -0.156
ENSG00000197948 E003 12.1122820 0.0013372188 0.480042246 0.74550372 5 141639308 141640981 1674 - 1.070 1.129 0.214
ENSG00000197948 E004 0.0000000       5 141640982 141640986 5 -      
ENSG00000197948 E005 7.3819298 0.0071280787 0.634407232 0.84377293 5 141640987 141641208 222 - 0.942 0.894 -0.183
ENSG00000197948 E006 22.7757502 0.0006206696 0.162259876 0.43068077 5 141641209 141641505 297 - 1.309 1.396 0.302
ENSG00000197948 E007 8.9431960 0.0016384415 0.088894711 0.30937642 5 141641506 141641563 58 - 0.879 1.043 0.614
ENSG00000197948 E008 8.1670304 0.0132551415 0.415206709 0.69532807 5 141641702 141641757 56 - 0.895 0.984 0.332
ENSG00000197948 E009 7.2262246 0.0023943409 0.022524359 0.13651295 5 141641758 141642396 639 - 0.738 0.984 0.949
ENSG00000197948 E010 2.1169731 0.0206528449 0.371630840 0.65963068 5 141642397 141642503 107 - 0.396 0.533 0.693
ENSG00000197948 E011 4.2546260 0.0034045597 0.015327760 0.10669688 5 141642504 141643000 497 - 0.490 0.808 1.377
ENSG00000197948 E012 8.7623936 0.0073564175 0.899571316 0.96725410 5 141643001 141643088 88 - 0.971 0.984 0.049
ENSG00000197948 E013 20.3567762 0.0007180689 0.962121175 0.99173616 5 141644218 141644438 221 - 1.316 1.320 0.015
ENSG00000197948 E014 10.8492566 0.0012420947 0.889053166 0.96300183 5 141644573 141644629 57 - 1.070 1.059 -0.040
ENSG00000197948 E015 11.8477159 0.0011210588 0.903556492 0.96904248 5 141644630 141644690 61 - 1.091 1.102 0.040
ENSG00000197948 E016 9.3476845 0.0016794906 0.417620745 0.69734672 5 141644859 141644938 80 - 1.047 0.975 -0.266
ENSG00000197948 E017 3.3398737 0.0042678458 0.740409175 0.89704147 5 141644939 141644942 4 - 0.600 0.645 0.195
ENSG00000197948 E018 12.1411594 0.0011947586 0.091383096 0.31396712 5 141645020 141645148 129 - 1.185 1.051 -0.483
ENSG00000197948 E019 7.1108858 0.0019593648 0.212356624 0.49759926 5 141645771 141645821 51 - 0.971 0.847 -0.471
ENSG00000197948 E020 9.8779486 0.0013805302 0.005010147 0.04969970 5 141645822 141645932 111 - 1.159 0.915 -0.892
ENSG00000197948 E021 9.2653055 0.0015476130 0.003811255 0.04107838 5 141646087 141646191 105 - 1.141 0.882 -0.952
ENSG00000197948 E022 6.2251184 0.0023649971 0.073002340 0.27454226 5 141646192 141646507 316 - 0.714 0.915 0.792
ENSG00000197948 E023 0.9868789 0.0120943527 0.877954340 0.95851479 5 141646508 141646602 95 - 0.278 0.302 0.167
ENSG00000197948 E024 5.8530250 0.0034907806 0.052775769 0.22831542 5 141646603 141646671 69 - 0.942 0.734 -0.811
ENSG00000197948 E025 6.0167587 0.0026081831 0.504443384 0.76358825 5 141646672 141646722 51 - 0.879 0.808 -0.275
ENSG00000197948 E026 6.6684950 0.0022547258 0.847660811 0.94600820 5 141647135 141647230 96 - 0.861 0.882 0.082
ENSG00000197948 E027 6.5867686 0.0022465535 0.131276734 0.38435912 5 141647398 141647520 123 - 0.761 0.926 0.639
ENSG00000197948 E028 4.1018900 0.1058784419 0.237649131 0.52657525 5 141647521 141647831 311 - 0.566 0.765 0.846
ENSG00000197948 E029 1.1158368 0.0237047846 0.680964984 0.86816715 5 141647884 141647967 84 - 0.278 0.343 0.430
ENSG00000197948 E030 8.3281570 0.0189587261 0.112976233 0.35365392 5 141647968 141648096 129 - 0.843 1.019 0.662
ENSG00000197948 E031 6.6406058 0.0023495450 0.524323950 0.77749060 5 141648957 141649020 64 - 0.912 0.847 -0.248
ENSG00000197948 E032 10.3184269 0.0014178636 0.344911437 0.63595957 5 141649172 141649308 137 - 1.091 1.010 -0.295
ENSG00000197948 E033 4.7583203 0.0031270758 0.087301286 0.30628424 5 141649395 141649530 136 - 0.861 0.664 -0.793
ENSG00000197948 E034 0.0000000       5 141649531 141649536 6 -      
ENSG00000197948 E035 3.1104957 0.0066802058 0.210058464 0.49447595 5 141649887 141649954 68 - 0.490 0.664 0.792
ENSG00000197948 E036 3.3384577 0.0232834877 0.763311064 0.90772940 5 141650359 141650404 46 - 0.600 0.645 0.195
ENSG00000197948 E037 5.1657797 0.1253427013 0.593034924 0.82056352 5 141651020 141651117 98 - 0.824 0.750 -0.295
ENSG00000197948 E038 3.1865474 0.0235788253 0.341085803 0.63266918 5 141651348 141651418 71 - 0.688 0.558 -0.570

Help

Please Click HERE to learn more details about the results from DEXseq.