ENSG00000198125

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000359787 ENSG00000198125 No_inf pgKDN_inf MB protein_coding protein_coding 39.84178 57.17955 25.26898 1.397672 0.5836208 -1.177813 3.601680 4.483085 4.166661 1.990097 2.0821432 -0.1053563 0.10122500 0.079450 0.165475 0.086025 8.380412e-01 2.741975e-07 FALSE TRUE
ENST00000406324 ENSG00000198125 No_inf pgKDN_inf MB protein_coding protein_coding 39.84178 57.17955 25.26898 1.397672 0.5836208 -1.177813 4.771941 12.830963 1.144842 1.980782 1.1448422 -3.4749857 0.09143333 0.222825 0.042850 -0.179975 3.432659e-02 2.741975e-07 FALSE TRUE
MSTRG.19315.1 ENSG00000198125 No_inf pgKDN_inf MB protein_coding   39.84178 57.17955 25.26898 1.397672 0.5836208 -1.177813 19.489601 14.048874 16.036910 1.832032 0.8914206 0.1908144 0.55013333 0.246300 0.634525 0.388225 1.839658e-05 2.741975e-07 FALSE FALSE
MSTRG.19315.2 ENSG00000198125 No_inf pgKDN_inf MB protein_coding   39.84178 57.17955 25.26898 1.397672 0.5836208 -1.177813 5.087046 15.261139 0.000000 5.240656 0.0000000 -10.5765920 0.08710000 0.261300 0.000000 -0.261300 2.741975e-07 2.741975e-07 FALSE TRUE
MSTRG.19315.3 ENSG00000198125 No_inf pgKDN_inf MB protein_coding   39.84178 57.17955 25.26898 1.397672 0.5836208 -1.177813 6.398810 9.789595 3.515225 5.677034 2.1249038 -1.4750068 0.15798333 0.177550 0.141150 -0.036400 1.000000e+00 2.741975e-07 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000198125 E001 85.7926958 0.0003071335 0.0911412256 0.31357558 22 35606764 35607271 508 - 1.931 1.882 -0.166
ENSG00000198125 E002 18.5237455 0.0009735759 0.7917149773 0.92032579 22 35607272 35607332 61 - 1.237 1.255 0.064
ENSG00000198125 E003 16.8337561 0.0009644664 0.1635516966 0.43244297 22 35607333 35607374 42 - 1.133 1.240 0.379
ENSG00000198125 E004 26.9790681 0.0006259698 0.6238266118 0.83809850 22 35607375 35607443 69 - 1.386 1.414 0.098
ENSG00000198125 E005 34.1597576 0.0004988424 0.9047481670 0.96949630 22 35610884 35610969 86 - 1.501 1.506 0.019
ENSG00000198125 E006 39.8388242 0.0004073717 0.2065752473 0.49020721 22 35610970 35611106 137 - 1.526 1.586 0.207
ENSG00000198125 E007 12.9077611 0.0013854739 0.0009265698 0.01416505 22 35611570 35611819 250 - 1.273 1.010 -0.943
ENSG00000198125 E008 0.0000000       22 35615574 35615713 140 -      
ENSG00000198125 E009 0.1186381 0.0118071318 0.2171473447   22 35617077 35617162 86 - 0.137 0.000 -11.849
ENSG00000198125 E010 13.1198093 0.0011589819 0.0765996590 0.28300569 22 35617163 35617265 103 - 0.995 1.150 0.564
ENSG00000198125 E011 0.1176306 0.0117477112 0.2171604467   22 35617266 35617329 64 - 0.137 0.000 -11.849
ENSG00000198125 E012 0.1268540 0.0123193140 1.0000000000   22 35617362 35617586 225 - 0.000 0.065 8.997
ENSG00000198125 E013 0.7460776 0.3681876353 0.8942077544 0.96500387 22 35620209 35620261 53 - 0.241 0.217 -0.192
ENSG00000198125 E014 0.0000000       22 35621966 35622096 131 -      
ENSG00000198125 E015 3.9060536 0.0173647337 0.0072127591 0.06435345 22 35622478 35622561 84 - 0.324 0.743 2.031
ENSG00000198125 E016 2.2108135 0.0070155870 0.2177289726 0.50423723 22 35623191 35623401 211 - 0.598 0.418 -0.869
ENSG00000198125 E017 0.0000000       22 35637106 35637208 103 -      
ENSG00000198125 E018 0.0000000       22 35637866 35637951 86 -      

Help

Please Click HERE to learn more details about the results from DEXseq.