ENSG00000198162

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000356554 ENSG00000198162 No_inf pgKDN_inf MAN1A2 protein_coding protein_coding 10.57375 9.919162 11.66787 0.346351 0.386767 0.234033 7.7327599 4.789461 9.7061504 0.4185525 1.1434245 1.017512 0.72835000 0.484400 0.84120 0.356800 0.14840333 0.03497284 FALSE TRUE
ENST00000421535 ENSG00000198162 No_inf pgKDN_inf MAN1A2 protein_coding protein_coding 10.57375 9.919162 11.66787 0.346351 0.386767 0.234033 0.5494523 0.000000 0.8046628 0.0000000 0.4676554 6.348131 0.04805833 0.000000 0.06550 0.065500 0.49635916 0.03497284 FALSE TRUE
MSTRG.1622.2 ENSG00000198162 No_inf pgKDN_inf MAN1A2 protein_coding   10.57375 9.919162 11.66787 0.346351 0.386767 0.234033 1.9413388 4.471991 1.0479493 0.3925665 1.0479493 -2.082869 0.19061667 0.453875 0.08435 -0.369525 0.03497284 0.03497284 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000198162 E001 2.3973294 0.2271847769 9.274007e-02 0.3162512485 1 117367449 117367642 194 + 0.683 0.302 -1.928
ENSG00000198162 E002 6.3324813 0.0025598320 3.761531e-01 0.6633784197 1 117367643 117367942 300 + 0.912 0.814 -0.376
ENSG00000198162 E003 17.5072941 0.0054436982 6.387338e-02 0.2545213866 1 117367943 117368485 543 + 1.333 1.192 -0.497
ENSG00000198162 E004 27.6838086 0.0005147767 5.517901e-01 0.7955374935 1 117402186 117402441 256 + 1.443 1.471 0.097
ENSG00000198162 E005 17.0638262 0.0010318972 3.412917e-01 0.6328886498 1 117405549 117405645 97 + 1.224 1.286 0.217
ENSG00000198162 E006 16.1541379 0.0157063024 9.758306e-01 0.9958834490 1 117414713 117414831 119 + 1.237 1.232 -0.016
ENSG00000198162 E007 6.6047632 0.0083194021 9.598803e-01 0.9907447801 1 117420569 117420596 28 + 0.886 0.876 -0.035
ENSG00000198162 E008 9.8086889 0.0014600172 6.231588e-01 0.8377491634 1 117420597 117420649 53 + 1.013 1.053 0.144
ENSG00000198162 E009 10.8679282 0.0040577209 6.553597e-01 0.8554447871 1 117442231 117442325 95 + 1.096 1.053 -0.156
ENSG00000198162 E010 8.9340555 0.0015850546 8.884537e-01 0.9627473362 1 117460489 117460612 124 + 0.993 1.001 0.032
ENSG00000198162 E011 5.4055866 0.0030187256 4.263446e-01 0.7049626577 1 117466334 117466427 94 + 0.762 0.846 0.335
ENSG00000198162 E012 6.8181136 0.0030254219 2.723316e-01 0.5660679019 1 117493147 117493262 116 + 0.948 0.831 -0.449
ENSG00000198162 E013 2.0410320 0.0070727196 3.632074e-02 0.1831453685 1 117496763 117496779 17 + 0.613 0.302 -1.629
ENSG00000198162 E014 10.1627108 0.0013369209 8.692313e-01 0.9550423678 1 117496780 117496982 203 + 1.043 1.053 0.037
ENSG00000198162 E015 11.2466083 0.0012358616 8.985754e-01 0.9666554457 1 117499382 117499554 173 + 1.096 1.081 -0.054
ENSG00000198162 E016 3.0510140 0.0312279960 6.678379e-01 0.8618078481 1 117502855 117502860 6 + 0.638 0.575 -0.276
ENSG00000198162 E017 6.5650088 0.0030816949 1.611556e-01 0.4292865452 1 117502861 117502970 110 + 0.948 0.797 -0.581
ENSG00000198162 E018 0.9854969 0.0160935566 4.327421e-01 0.7101885893 1 117514849 117515939 1091 + 0.235 0.353 0.809
ENSG00000198162 E019 7.9358556 0.0019673471 7.084554e-01 0.8818163307 1 117522825 117522937 113 + 0.971 0.931 -0.151
ENSG00000198162 E020 16.2924479 0.0008974993 5.627099e-02 0.2365307340 1 117522938 117523249 312 + 1.303 1.163 -0.495
ENSG00000198162 E021 111.5863202 0.0026339330 2.005429e-02 0.1271732262 1 117523250 117525088 1839 + 2.088 2.012 -0.255
ENSG00000198162 E022 204.7139029 0.0001349976 9.402340e-06 0.0003236157 1 117525089 117528872 3784 + 2.277 2.346 0.231

Help

Please Click HERE to learn more details about the results from DEXseq.