ENSG00000198231

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000389924 ENSG00000198231 No_inf pgKDN_inf DDX42 protein_coding protein_coding 54.32556 59.64175 50.03411 1.749602 1.690496 -0.2533641 31.654929 28.384536 34.5766451 0.5319954 1.8146749 0.2846017 0.59097500 0.476800 0.694200 0.217400 0.02288048 0.021274 FALSE TRUE
ENST00000578593 ENSG00000198231 No_inf pgKDN_inf DDX42 protein_coding retained_intron 54.32556 59.64175 50.03411 1.749602 1.690496 -0.2533641 1.736315 3.616130 0.4029408 0.5402098 0.1493794 -3.1344238 0.03038333 0.060450 0.008275 -0.052175 0.02127400 0.021274 FALSE TRUE
ENST00000579539 ENSG00000198231 No_inf pgKDN_inf DDX42 protein_coding retained_intron 54.32556 59.64175 50.03411 1.749602 1.690496 -0.2533641 6.886452 7.382069 4.8819082 1.1686171 2.0272349 -0.5955810 0.12452500 0.122575 0.093950 -0.028625 0.83244464 0.021274 FALSE TRUE
MSTRG.13138.6 ENSG00000198231 No_inf pgKDN_inf DDX42 protein_coding   54.32556 59.64175 50.03411 1.749602 1.690496 -0.2533641 7.013565 9.230543 5.3972097 0.4192452 0.3479980 -0.7730934 0.12787500 0.155025 0.107900 -0.047125 0.62998610 0.021274 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000198231 E001 0.1176306 1.172290e-02 0.4345912943   17 63773603 63773861 259 + 0.104 0.000 -10.108
ENSG00000198231 E002 0.2346346 1.558445e-02 0.1782148613   17 63773863 63773883 21 + 0.188 0.000 -13.359
ENSG00000198231 E003 0.3618970 1.643751e-02 0.4611316741   17 63773884 63774091 208 + 0.188 0.087 -1.299
ENSG00000198231 E004 0.0000000       17 63774092 63774169 78 +      
ENSG00000198231 E005 0.0000000       17 63774170 63774188 19 +      
ENSG00000198231 E006 0.0000000       17 63774189 63774189 1 +      
ENSG00000198231 E007 0.9725583 1.213769e-02 0.3186304064 0.61126173 17 63774190 63774265 76 + 0.372 0.221 -1.036
ENSG00000198231 E008 11.9118163 1.153213e-03 0.0023462715 0.02876590 17 63774266 63774376 111 + 1.231 0.983 -0.896
ENSG00000198231 E009 2.1797242 6.841977e-03 0.0648373022 0.25658046 17 63775108 63775178 71 + 0.629 0.366 -1.299
ENSG00000198231 E010 5.9834351 1.912338e-02 0.2956456401 0.58869829 17 63787034 63787035 2 + 0.906 0.784 -0.476
ENSG00000198231 E011 6.2174430 3.716163e-02 0.2429107721 0.53258871 17 63787036 63787037 2 + 0.934 0.784 -0.582
ENSG00000198231 E012 32.8877799 5.168219e-04 0.3852650481 0.67132609 17 63787038 63787270 233 + 1.550 1.507 -0.148
ENSG00000198231 E013 19.3801364 7.065065e-04 0.1870871368 0.46495055 17 63792412 63792485 74 + 1.251 1.342 0.316
ENSG00000198231 E014 15.1362358 1.023304e-03 0.8544600947 0.94868870 17 63792486 63792528 43 + 1.195 1.210 0.054
ENSG00000198231 E015 11.7824723 3.512822e-03 0.5437943527 0.79053921 17 63792529 63792562 34 + 1.130 1.080 -0.179
ENSG00000198231 E016 18.8532919 1.444387e-02 0.1838101384 0.46079836 17 63798038 63798099 62 + 1.351 1.244 -0.375
ENSG00000198231 E017 16.9739016 2.631011e-03 0.0102768638 0.08171493 17 63798100 63798574 475 + 1.130 1.324 0.685
ENSG00000198231 E018 34.0452327 7.342638e-03 0.2127123866 0.49793532 17 63798575 63799479 905 + 1.493 1.573 0.273
ENSG00000198231 E019 5.0820802 3.386563e-03 0.1744119380 0.44813175 17 63799480 63799523 44 + 0.681 0.842 0.648
ENSG00000198231 E020 4.8450887 2.058194e-02 0.1004218924 0.33089897 17 63799524 63799588 65 + 0.629 0.842 0.871
ENSG00000198231 E021 20.1873433 1.690590e-02 0.1296902544 0.38201884 17 63799589 63799625 37 + 1.387 1.266 -0.422
ENSG00000198231 E022 29.1794048 2.943225e-02 0.0041302973 0.04344061 17 63799626 63800150 525 + 1.313 1.568 0.880
ENSG00000198231 E023 5.9201147 2.700085e-03 0.4767778355 0.74318092 17 63800151 63800176 26 + 0.789 0.869 0.311
ENSG00000198231 E024 15.4115094 8.863117e-04 0.0007399604 0.01188122 17 63800177 63800467 291 + 1.043 1.305 0.934
ENSG00000198231 E025 45.5177368 5.056302e-03 0.3291059881 0.62154261 17 63800468 63800617 150 + 1.691 1.642 -0.167
ENSG00000198231 E026 0.9896168 1.342688e-02 0.6835448096 0.86899646 17 63805044 63805070 27 + 0.259 0.323 0.438
ENSG00000198231 E027 34.7327085 4.103001e-04 0.5194975000 0.77418830 17 63805071 63805175 105 + 1.566 1.536 -0.105
ENSG00000198231 E028 1.7513344 4.556824e-02 0.0911026530 0.31348889 17 63805176 63805287 112 + 0.259 0.535 1.576
ENSG00000198231 E029 6.7445536 5.441087e-03 0.0022390635 0.02783809 17 63805508 63806534 1027 + 0.656 1.002 1.358
ENSG00000198231 E030 29.5540415 4.660358e-04 0.2906222279 0.58417427 17 63806535 63806654 120 + 1.512 1.456 -0.191
ENSG00000198231 E031 40.0702132 4.026288e-04 0.1285312999 0.38017882 17 63807724 63807900 177 + 1.648 1.578 -0.237
ENSG00000198231 E032 43.1874671 6.938193e-04 0.3678201977 0.65643144 17 63808820 63808948 129 + 1.663 1.624 -0.135
ENSG00000198231 E033 40.9638297 3.597667e-04 0.7440671612 0.89873493 17 63809560 63809659 100 + 1.609 1.626 0.058
ENSG00000198231 E034 0.7511446 1.425722e-02 0.1517812452 0.41535185 17 63810263 63810512 250 + 0.104 0.323 2.023
ENSG00000198231 E035 24.6148138 5.902715e-03 0.2515963447 0.54280560 17 63810513 63810560 48 + 1.445 1.371 -0.256
ENSG00000198231 E036 42.9649575 4.413782e-04 0.4264443621 0.70504341 17 63811076 63811173 98 + 1.658 1.624 -0.118
ENSG00000198231 E037 0.7612770 2.460359e-02 0.0193074832 0.12421745 17 63811174 63811271 98 + 0.000 0.366 13.676
ENSG00000198231 E038 3.0104918 4.537584e-03 0.0038709419 0.04151124 17 63811281 63811931 651 + 0.319 0.733 2.023
ENSG00000198231 E039 79.8438239 1.990431e-04 0.5568424388 0.79899809 17 63811932 63812208 277 + 1.891 1.913 0.072
ENSG00000198231 E040 23.4757787 1.461546e-03 0.0462708737 0.21095294 17 63813228 63813271 44 + 1.449 1.328 -0.419
ENSG00000198231 E041 56.9466667 2.975572e-04 0.2836748976 0.57740968 17 63813272 63813454 183 + 1.781 1.741 -0.137
ENSG00000198231 E042 47.5248383 3.031047e-04 0.6168911198 0.83407212 17 63815563 63815673 111 + 1.693 1.673 -0.068
ENSG00000198231 E043 0.4791531 2.460753e-02 0.2306158081   17 63815674 63815970 297 + 0.259 0.087 -1.884
ENSG00000198231 E044 0.3719991 1.660961e-02 0.7230359653   17 63816589 63816867 279 + 0.104 0.159 0.701
ENSG00000198231 E045 57.3368482 2.595147e-04 0.5442377039 0.79075877 17 63816868 63816966 99 + 1.747 1.773 0.087
ENSG00000198231 E046 0.4899767 5.304606e-02 0.8331823711   17 63816968 63817072 105 + 0.188 0.159 -0.299
ENSG00000198231 E047 1.1243720 1.080650e-02 0.1634059666 0.43220722 17 63817073 63817345 273 + 0.188 0.406 1.508
ENSG00000198231 E048 1.6324764 8.031573e-03 0.0254640388 0.14708253 17 63817346 63817693 348 + 0.188 0.535 2.160
ENSG00000198231 E049 433.2284556 7.609427e-05 0.7652269266 0.90875604 17 63817694 63818934 1241 + 2.630 2.636 0.018
ENSG00000198231 E050 96.8637687 1.996337e-04 0.8535474079 0.94832158 17 63818935 63819317 383 + 1.982 1.990 0.024

Help

Please Click HERE to learn more details about the results from DEXseq.