ENSG00000198252

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000354586 ENSG00000198252 No_inf pgKDN_inf STYX protein_coding protein_coding 11.29409 10.39919 12.83772 0.5004964 0.2895424 0.3036543 9.8673947 6.899077 12.68529 0.6034241 0.4111647 0.8777284 0.86660833 0.669725 0.987525 0.317800 4.225393e-05 3.844118e-07 FALSE TRUE
ENST00000556861 ENSG00000198252 No_inf pgKDN_inf STYX protein_coding protein_coding_CDS_not_defined 11.29409 10.39919 12.83772 0.5004964 0.2895424 0.3036543 0.9611464 2.883439 0.00000 0.2742170 0.0000000 -8.1766415 0.09205833 0.276175 0.000000 -0.276175 3.844118e-07 3.844118e-07   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000198252 E001 0.4719109 0.0157036361 1.022374e-01   14 52730166 52730179 14 + 0.259 0.000 -9.624
ENSG00000198252 E002 2.1401270 0.0065963561 5.728509e-03 0.054586817 14 52730180 52730210 31 + 0.629 0.201 -2.468
ENSG00000198252 E003 15.6454259 0.0009195159 4.280635e-04 0.007726633 14 52730211 52730458 248 + 1.313 1.042 -0.965
ENSG00000198252 E004 7.4238351 0.0019356936 9.655498e-01 0.992776674 14 52730459 52730531 73 + 0.920 0.922 0.006
ENSG00000198252 E005 0.0000000       14 52731594 52731712 119 +      
ENSG00000198252 E006 6.3195138 0.0023839532 9.617203e-01 0.991684772 14 52744852 52744884 33 + 0.864 0.856 -0.030
ENSG00000198252 E007 7.6732694 0.0129532359 5.758765e-01 0.810235521 14 52746426 52746479 54 + 0.910 0.966 0.211
ENSG00000198252 E008 10.0387639 0.0501405202 4.704625e-01 0.738121093 14 52750683 52750780 98 + 1.079 0.979 -0.364
ENSG00000198252 E009 5.6763076 0.0027764079 2.150457e-01 0.500681008 14 52756551 52756611 61 + 0.876 0.734 -0.561
ENSG00000198252 E010 5.9360889 0.0168795694 4.317241e-01 0.709334270 14 52757319 52757355 37 + 0.876 0.778 -0.380
ENSG00000198252 E011 6.0392454 0.0024475199 2.051174e-01 0.488359168 14 52757743 52757782 40 + 0.899 0.757 -0.555
ENSG00000198252 E012 6.1826447 0.0122773951 4.638007e-01 0.733531354 14 52757874 52757924 51 + 0.887 0.799 -0.342
ENSG00000198252 E013 8.8733891 0.0127597137 8.876260e-01 0.962400736 14 52759682 52759754 73 + 0.998 0.979 -0.069
ENSG00000198252 E014 11.6230660 0.0012196891 1.976998e-01 0.479073475 14 52768840 52768933 94 + 1.141 1.030 -0.401
ENSG00000198252 E015 118.7760519 0.0003110349 6.524617e-01 0.853577682 14 52771033 52773615 2583 + 2.070 2.078 0.025
ENSG00000198252 E016 82.2522208 0.0002207488 6.771441e-05 0.001708989 14 52773616 52774989 1374 + 1.865 1.976 0.374

Help

Please Click HERE to learn more details about the results from DEXseq.