ENSG00000198258

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000358666 ENSG00000198258 No_inf pgKDN_inf UBL5 protein_coding protein_coding 666.0925 513.2793 746.4648 12.21622 16.57803 0.5403213 74.23864 48.19620 88.65992 2.917758 3.615659 0.8792261 0.1097833 0.093750 0.118975 0.025225 0.41680986 0.02103809   FALSE
ENST00000586895 ENSG00000198258 No_inf pgKDN_inf UBL5 protein_coding protein_coding 666.0925 513.2793 746.4648 12.21622 16.57803 0.5403213 430.97550 359.68874 447.36183 13.988366 11.117238 0.3146853 0.6552833 0.703700 0.600475 -0.103225 0.17890063 0.02103809   FALSE
ENST00000589960 ENSG00000198258 No_inf pgKDN_inf UBL5 protein_coding protein_coding_CDS_not_defined 666.0925 513.2793 746.4648 12.21622 16.57803 0.5403213 145.41926 77.74077 201.70800 10.524956 26.139758 1.3754109 0.2090333 0.150625 0.268575 0.117950 0.02103809 0.02103809   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000198258 E001 0.000000       19 9827892 9827893 2 +      
ENSG00000198258 E002 0.000000       19 9827894 9827895 2 +      
ENSG00000198258 E003 5.570190 0.0200618421 0.13466481 0.39014212 19 9827896 9827914 19 + 0.892 0.708 -0.730
ENSG00000198258 E004 8.611041 0.0190280801 0.16663999 0.43696815 19 9827915 9827917 3 + 1.045 0.894 -0.562
ENSG00000198258 E005 12.144292 0.0013249653 0.19047988 0.46964833 19 9827918 9827925 8 + 1.164 1.056 -0.388
ENSG00000198258 E006 63.097649 0.0002478172 0.33792375 0.62974947 19 9827926 9827943 18 + 1.822 1.786 -0.120
ENSG00000198258 E007 146.807516 0.0001118501 0.22926163 0.51797071 19 9827944 9827984 41 + 2.181 2.153 -0.094
ENSG00000198258 E008 16.885300 0.0084898278 0.17586774 0.44999320 19 9827985 9828064 80 + 1.298 1.190 -0.380
ENSG00000198258 E009 203.803780 0.0001040188 0.03037725 0.16400064 19 9828327 9828389 63 + 2.329 2.287 -0.141
ENSG00000198258 E010 87.783662 0.0006761652 0.03433088 0.17694274 19 9828390 9828393 4 + 1.978 1.909 -0.232
ENSG00000198258 E011 10.587940 0.0019197653 0.01271323 0.09386741 19 9828394 9828591 198 + 0.949 1.166 0.792
ENSG00000198258 E012 207.460741 0.0001098097 0.45717189 0.72921979 19 9828592 9828675 84 + 2.311 2.326 0.049
ENSG00000198258 E013 1.840615 0.0075350896 0.50021926 0.76035208 19 9828676 9828805 130 + 0.404 0.503 0.511
ENSG00000198258 E014 157.456921 0.0001151099 0.01894352 0.12251798 19 9828837 9828874 38 + 2.173 2.227 0.179
ENSG00000198258 E015 11.728757 0.0376104657 0.01585977 0.10913251 19 9828875 9829964 1090 + 0.960 1.227 0.966
ENSG00000198258 E016 181.066489 0.0001117731 0.01256999 0.09317621 19 9829965 9830115 151 + 2.234 2.286 0.176

Help

Please Click HERE to learn more details about the results from DEXseq.