ENSG00000198399

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000361999 ENSG00000198399 No_inf pgKDN_inf ITSN2 protein_coding protein_coding 43.05764 63.63195 29.14387 13.38313 1.596298 -1.12629 2.089447 0.000000 3.770041 0.0000000 2.1804256 8.562258199 0.06713333 0.000000 0.118625 0.118625 3.181529e-01 3.820375e-05 FALSE TRUE
ENST00000416160 ENSG00000198399 No_inf pgKDN_inf ITSN2 protein_coding protein_coding 43.05764 63.63195 29.14387 13.38313 1.596298 -1.12629 7.736282 10.395511 8.161643 0.6107619 0.7621149 -0.348649702 0.20972500 0.191575 0.283150 0.091575 6.303899e-01 3.820375e-05 FALSE FALSE
ENST00000449392 ENSG00000198399 No_inf pgKDN_inf ITSN2 protein_coding nonsense_mediated_decay 43.05764 63.63195 29.14387 13.38313 1.596298 -1.12629 12.528565 23.000141 0.000000 13.3489807 0.0000000 -11.168054095 0.18119167 0.265200 0.000000 -0.265200 8.171573e-01 3.820375e-05   FALSE
MSTRG.15923.1 ENSG00000198399 No_inf pgKDN_inf ITSN2 protein_coding   43.05764 63.63195 29.14387 13.38313 1.596298 -1.12629 3.895634 3.900127 3.886573 1.5029624 2.4156691 -0.005009514 0.10807500 0.061350 0.148725 0.087375 9.971058e-01 3.820375e-05 FALSE TRUE
MSTRG.15923.16 ENSG00000198399 No_inf pgKDN_inf ITSN2 protein_coding   43.05764 63.63195 29.14387 13.38313 1.596298 -1.12629 4.681711 3.359542 5.993535 1.3290283 0.9288131 0.833259961 0.14105833 0.063375 0.203100 0.139725 3.828867e-01 3.820375e-05 FALSE TRUE
MSTRG.15923.18 ENSG00000198399 No_inf pgKDN_inf ITSN2 protein_coding   43.05764 63.63195 29.14387 13.38313 1.596298 -1.12629 3.550060 7.738845 2.212074 1.2620754 0.6816390 -1.802074173 0.07968333 0.136350 0.075425 -0.060925 6.835463e-01 3.820375e-05   FALSE
MSTRG.15923.5 ENSG00000198399 No_inf pgKDN_inf ITSN2 protein_coding   43.05764 63.63195 29.14387 13.38313 1.596298 -1.12629 2.224317 5.921676 0.000000 1.0130821 0.0000000 -9.212296020 0.04709167 0.111000 0.000000 -0.111000 3.820375e-05 3.820375e-05 TRUE TRUE
MSTRG.15923.7 ENSG00000198399 No_inf pgKDN_inf ITSN2 protein_coding   43.05764 63.63195 29.14387 13.38313 1.596298 -1.12629 2.551785 3.163165 1.916919 1.0847086 1.2897171 -0.719626718 0.07290833 0.067000 0.066800 -0.000200 8.734559e-01 3.820375e-05 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000198399 E001 0.0000000       2 24202864 24202865 2 -      
ENSG00000198399 E002 1.1060203 0.0673567902 9.713625e-01 9.945061e-01 2 24202866 24202883 18 - 0.323 0.319 -0.027
ENSG00000198399 E003 7.1437654 0.0019437766 9.061149e-01 9.700390e-01 2 24202884 24202975 92 - 0.898 0.912 0.051
ENSG00000198399 E004 28.9923618 0.0147326282 3.965884e-01 6.812624e-01 2 24202976 24203281 306 - 1.435 1.496 0.210
ENSG00000198399 E005 47.8776094 0.0004304778 2.718575e-03 3.203487e-02 2 24203282 24203783 502 - 1.602 1.735 0.454
ENSG00000198399 E006 2.2506010 0.0098153705 5.904563e-02 2.438226e-01 2 24203784 24204244 461 - 0.323 0.606 1.458
ENSG00000198399 E007 13.1810205 0.0011229310 7.050615e-01 8.801566e-01 2 24204245 24204362 118 - 1.128 1.160 0.113
ENSG00000198399 E008 10.8225464 0.0013631004 9.348818e-01 9.812575e-01 2 24204363 24204418 56 - 1.071 1.065 -0.020
ENSG00000198399 E009 10.9534821 0.0012943411 8.229091e-01 9.356232e-01 2 24205214 24205265 52 - 1.061 1.081 0.075
ENSG00000198399 E010 9.8522382 0.0014159830 8.049657e-01 9.278227e-01 2 24205266 24205297 32 - 1.017 1.040 0.087
ENSG00000198399 E011 5.0345382 0.0029916968 2.025983e-05 6.247534e-04 2 24205298 24205693 396 - 0.377 0.934 2.458
ENSG00000198399 E012 4.0445432 0.0040082608 2.093752e-06 8.836026e-05 2 24206244 24206275 32 - 0.191 0.875 3.558
ENSG00000198399 E013 11.4422268 0.0013441255 8.664208e-01 9.539942e-01 2 24208237 24208319 83 - 1.081 1.097 0.057
ENSG00000198399 E014 14.5095058 0.0022379172 9.716234e-01 9.945632e-01 2 24209100 24209221 122 - 1.187 1.185 -0.005
ENSG00000198399 E015 13.7861324 0.0026982912 8.319147e-01 9.392783e-01 2 24209818 24210033 216 - 1.154 1.173 0.066
ENSG00000198399 E016 1.0155193 0.0110148205 5.689697e-03 5.431693e-02 2 24210034 24210329 296 - 0.000 0.437 13.804
ENSG00000198399 E017 0.0000000       2 24210780 24210947 168 -      
ENSG00000198399 E018 0.0000000       2 24212650 24212748 99 -      
ENSG00000198399 E019 0.0000000       2 24216049 24216232 184 -      
ENSG00000198399 E020 1.1161873 0.0122285324 5.231853e-01 7.766349e-01 2 24217907 24218013 107 - 0.262 0.362 0.651
ENSG00000198399 E021 0.0000000       2 24220319 24220944 626 -      
ENSG00000198399 E022 4.7547141 0.0029125953 3.445626e-03 3.829956e-02 2 24220945 24221066 122 - 0.506 0.875 1.558
ENSG00000198399 E023 0.1271363 0.0123522060 6.867173e-01   2 24238933 24238936 4 - 0.000 0.085 10.982
ENSG00000198399 E024 0.7606477 0.0258008238 2.143249e-02 1.325512e-01 2 24238937 24238942 6 - 0.000 0.362 13.364
ENSG00000198399 E025 2.3235693 0.1556355472 6.794891e-01 8.676012e-01 2 24238943 24238968 26 - 0.576 0.470 -0.502
ENSG00000198399 E026 241.9807886 0.0002064397 5.060479e-02 2.223463e-01 2 24238969 24242206 3238 - 2.399 2.366 -0.108
ENSG00000198399 E027 25.6456665 0.0005596101 3.128934e-03 3.561002e-02 2 24246129 24246287 159 - 1.308 1.487 0.620
ENSG00000198399 E028 10.3967605 0.0379295976 1.752936e-01 4.493268e-01 2 24246288 24246320 33 - 0.955 1.112 0.575
ENSG00000198399 E029 22.9222431 0.0006485233 4.950108e-01 7.563474e-01 2 24246797 24246893 97 - 1.348 1.392 0.152
ENSG00000198399 E030 20.3680746 0.0039196457 2.912769e-01 5.848308e-01 2 24248629 24248750 122 - 1.364 1.293 -0.245
ENSG00000198399 E031 14.3427560 0.0013340809 2.978789e-01 5.909369e-01 2 24248837 24248882 46 - 1.224 1.147 -0.275
ENSG00000198399 E032 27.3919975 0.0007850453 5.782916e-01 8.115331e-01 2 24252345 24252511 167 - 1.465 1.435 -0.103
ENSG00000198399 E033 17.3410663 0.0008341784 8.499500e-01 9.467998e-01 2 24254367 24254431 65 - 1.265 1.253 -0.041
ENSG00000198399 E034 23.8079208 0.0006239430 2.631245e-01 5.560224e-01 2 24257888 24258093 206 - 1.348 1.418 0.242
ENSG00000198399 E035 18.4553762 0.0316880325 8.489306e-01 9.464293e-01 2 24261106 24261250 145 - 1.271 1.293 0.078
ENSG00000198399 E036 6.2202359 0.0949786527 2.671882e-01 5.604197e-01 2 24261561 24261564 4 - 0.941 0.777 -0.633
ENSG00000198399 E037 24.8480296 0.0006160173 6.903011e-02 2.654595e-01 2 24261565 24261742 178 - 1.465 1.360 -0.363
ENSG00000198399 E038 5.3772060 0.0068492217 2.143985e-03 2.691660e-02 2 24263284 24263582 299 - 0.542 0.923 1.569
ENSG00000198399 E039 23.9535990 0.0005757593 6.218451e-01 8.369955e-01 2 24270671 24270768 98 - 1.408 1.380 -0.097
ENSG00000198399 E040 8.1494065 0.0021058597 3.275881e-01 6.201633e-01 2 24271766 24271804 39 - 0.898 0.995 0.365
ENSG00000198399 E041 24.7576140 0.0005644884 5.494848e-01 7.941938e-01 2 24271805 24271941 137 - 1.384 1.421 0.129
ENSG00000198399 E042 17.7505392 0.0010848583 4.832144e-01 7.478771e-01 2 24275713 24275849 137 - 1.238 1.289 0.178
ENSG00000198399 E043 0.3807797 0.0343321198 1.628223e-01   2 24284763 24284843 81 - 0.000 0.218 12.400
ENSG00000198399 E044 12.4088038 0.0011148791 7.388900e-01 8.964798e-01 2 24286212 24286322 111 - 1.137 1.112 -0.091
ENSG00000198399 E045 6.5394314 0.0020599233 5.341944e-01 7.843635e-01 2 24286323 24286351 29 - 0.833 0.900 0.259
ENSG00000198399 E046 0.7264369 0.0225867032 2.697240e-01 5.633438e-01 2 24293261 24293687 427 - 0.323 0.156 -1.349
ENSG00000198399 E047 10.3097634 0.0054428311 5.169139e-01 7.725512e-01 2 24293688 24293775 88 - 1.081 1.023 -0.212
ENSG00000198399 E048 0.2340080 0.2521998899 2.169139e-01   2 24294904 24295003 100 - 0.191 0.000 -12.302
ENSG00000198399 E049 20.4250506 0.0402168246 8.635448e-01 9.527896e-01 2 24295664 24295804 141 - 1.326 1.326 0.000
ENSG00000198399 E050 27.5231798 0.0005570124 6.178758e-01 8.345971e-01 2 24298665 24298814 150 - 1.465 1.439 -0.091
ENSG00000198399 E051 30.4502530 0.0004591363 4.290090e-01 7.074378e-01 2 24299909 24300171 263 - 1.515 1.475 -0.139
ENSG00000198399 E052 6.9953867 0.0019796769 5.998606e-01 8.245853e-01 2 24301154 24301239 86 - 0.927 0.875 -0.197
ENSG00000198399 E053 11.5048919 0.0014725740 1.662685e-01 4.364397e-01 2 24301965 24302102 138 - 1.154 1.040 -0.410
ENSG00000198399 E054 8.8126876 0.0141758300 3.531729e-01 6.429713e-01 2 24303799 24303862 64 - 1.039 0.945 -0.349
ENSG00000198399 E055 13.9412980 0.0010098265 9.370442e-02 3.183129e-01 2 24308617 24308756 140 - 1.238 1.112 -0.450
ENSG00000198399 E056 0.0000000       2 24308878 24308952 75 -      
ENSG00000198399 E057 7.9623997 0.0123957546 4.307639e-01 7.085511e-01 2 24310284 24310343 60 - 0.993 0.912 -0.304
ENSG00000198399 E058 6.6189144 0.0645442389 6.578789e-01 8.569506e-01 2 24310344 24310380 37 - 0.913 0.850 -0.241
ENSG00000198399 E059 15.0702847 0.0316490506 4.470000e-01 7.211636e-01 2 24310489 24310692 204 - 1.245 1.166 -0.278
ENSG00000198399 E060 0.1272623 0.0123216943 6.868285e-01   2 24311620 24311662 43 - 0.000 0.085 10.982
ENSG00000198399 E061 10.6727756 0.0061972955 4.333276e-01 7.108212e-01 2 24312212 24312375 164 - 1.100 1.032 -0.249
ENSG00000198399 E062 6.0788017 0.0330177430 4.961227e-02 2.196870e-01 2 24313460 24313523 64 - 0.968 0.727 -0.934
ENSG00000198399 E063 6.8479466 0.0082153374 2.584170e-01 5.507933e-01 2 24315132 24315224 93 - 0.955 0.836 -0.452
ENSG00000198399 E064 0.7162422 0.0135208709 4.899184e-02 2.181937e-01 2 24321814 24321880 67 - 0.377 0.085 -2.671
ENSG00000198399 E065 0.0000000       2 24326660 24326681 22 -      
ENSG00000198399 E066 3.7915262 0.0036602671 3.930064e-01 6.779813e-01 2 24328052 24328115 64 - 0.734 0.629 -0.442
ENSG00000198399 E067 6.1142203 0.0022899679 2.543598e-01 5.460373e-01 2 24360304 24360701 398 - 0.913 0.793 -0.465

Help

Please Click HERE to learn more details about the results from DEXseq.