ENSG00000198408

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000361464 ENSG00000198408 No_inf pgKDN_inf OGA protein_coding protein_coding 42.82899 72.68203 31.19111 2.217706 1.160432 -1.2202 12.622235 11.032039 15.328462 3.8345961 0.6836731 0.4741472 0.37092500 0.149925 0.495225 0.345300 2.044101e-01 3.512143e-07 FALSE TRUE
ENST00000439817 ENSG00000198408 No_inf pgKDN_inf OGA protein_coding protein_coding 42.82899 72.68203 31.19111 2.217706 1.160432 -1.2202 3.829014 11.025159 0.000000 2.4752218 0.0000000 -10.1078917 0.05750833 0.152350 0.000000 -0.152350 3.512143e-07 3.512143e-07 FALSE TRUE
ENST00000462994 ENSG00000198408 No_inf pgKDN_inf OGA protein_coding protein_coding_CDS_not_defined 42.82899 72.68203 31.19111 2.217706 1.160432 -1.2202 3.242481 6.062422 1.730181 0.3166416 0.5947225 -1.8030347 0.07300833 0.083275 0.057375 -0.025900 8.101762e-01 3.512143e-07   FALSE
ENST00000482611 ENSG00000198408 No_inf pgKDN_inf OGA protein_coding protein_coding_CDS_not_defined 42.82899 72.68203 31.19111 2.217706 1.160432 -1.2202 1.912379 0.000000 4.421542 0.0000000 2.2847541 8.7916651 0.06147500 0.000000 0.135275 0.135275 5.646507e-03 3.512143e-07 TRUE TRUE
ENST00000492204 ENSG00000198408 No_inf pgKDN_inf OGA protein_coding protein_coding_CDS_not_defined 42.82899 72.68203 31.19111 2.217706 1.160432 -1.2202 6.534040 12.617652 3.805893 0.3525868 0.2705890 -1.7264936 0.14230833 0.173850 0.122575 -0.051275 6.248360e-01 3.512143e-07   FALSE
MSTRG.3907.2 ENSG00000198408 No_inf pgKDN_inf OGA protein_coding   42.82899 72.68203 31.19111 2.217706 1.160432 -1.2202 2.260427 6.781282 0.000000 2.4467062 0.0000000 -9.4075400 0.03130833 0.093925 0.000000 -0.093925 5.032673e-02 3.512143e-07 TRUE TRUE
MSTRG.3907.7 ENSG00000198408 No_inf pgKDN_inf OGA protein_coding   42.82899 72.68203 31.19111 2.217706 1.160432 -1.2202 3.994472 8.488205 1.952621 1.2659489 0.4079334 -2.1143769 0.08208333 0.118600 0.062075 -0.056525 5.131050e-01 3.512143e-07 TRUE TRUE
MSTRG.3907.8 ENSG00000198408 No_inf pgKDN_inf OGA protein_coding   42.82899 72.68203 31.19111 2.217706 1.160432 -1.2202 2.853651 5.581793 1.597394 0.5880416 0.5390877 -1.7985873 0.06205833 0.076975 0.052775 -0.024200 8.204609e-01 3.512143e-07 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000198408 E001 0.0000000       10 101784443 101784449 7 -      
ENSG00000198408 E002 0.8706000 0.0287007765 9.961033e-01 1.000000e+00 10 101784450 101784453 4 - 0.249 0.249 0.000
ENSG00000198408 E003 425.4793713 0.0000689669 6.227274e-11 6.446483e-09 10 101784454 101786101 1648 - 2.511 2.602 0.305
ENSG00000198408 E004 25.8709746 0.0030355360 9.562952e-01 9.896398e-01 10 101786102 101786133 32 - 1.384 1.379 -0.018
ENSG00000198408 E005 19.4333921 0.0012706787 6.327063e-01 8.427347e-01 10 101786134 101786143 10 - 1.237 1.271 0.120
ENSG00000198408 E006 111.0640156 0.0006358974 3.119995e-01 6.053669e-01 10 101786144 101786533 390 - 1.976 2.007 0.105
ENSG00000198408 E007 18.5267070 0.0007722448 9.568029e-01 9.897505e-01 10 101786534 101786562 29 - 1.246 1.241 -0.019
ENSG00000198408 E008 18.1968990 0.0008074146 4.797337e-01 7.453235e-01 10 101786563 101786587 25 - 1.196 1.249 0.187
ENSG00000198408 E009 51.0409361 0.0003075816 5.419774e-01 7.894086e-01 10 101787364 101787523 160 - 1.647 1.674 0.091
ENSG00000198408 E010 7.4874513 0.0024083280 3.571859e-01 6.468311e-01 10 101787524 101787965 442 - 0.807 0.910 0.396
ENSG00000198408 E011 51.0753868 0.0003211965 3.447404e-01 6.358616e-01 10 101790896 101791088 193 - 1.635 1.678 0.145
ENSG00000198408 E012 3.8975805 0.0079367188 4.003756e-02 1.939578e-01 10 101791089 101791353 265 - 0.406 0.714 1.434
ENSG00000198408 E013 30.0815703 0.0105363774 7.726755e-02 2.844050e-01 10 101791354 101791439 86 - 1.530 1.406 -0.426
ENSG00000198408 E014 0.8604067 0.0609911329 4.406548e-01 7.163479e-01 10 101791440 101791453 14 - 0.335 0.209 -0.905
ENSG00000198408 E015 2.6393715 0.0051836402 1.221207e-01 3.695715e-01 10 101792608 101792838 231 - 0.335 0.578 1.264
ENSG00000198408 E016 29.4235027 0.0067324127 5.110576e-01 7.683696e-01 10 101792839 101792901 63 - 1.466 1.422 -0.153
ENSG00000198408 E017 21.5590145 0.0087848293 3.979647e-01 6.820192e-01 10 101792902 101792943 42 - 1.256 1.322 0.232
ENSG00000198408 E018 28.5065489 0.0028674569 7.314381e-06 2.609086e-04 10 101792944 101793685 742 - 1.163 1.488 1.135
ENSG00000198408 E019 6.2759427 0.0046458658 3.950899e-02 1.926730e-01 10 101793686 101793744 59 - 0.612 0.875 1.072
ENSG00000198408 E020 9.1558337 0.0016254695 1.544782e-02 1.072834e-01 10 101793745 101793912 168 - 0.751 1.019 1.025
ENSG00000198408 E021 26.6979866 0.0103753372 5.785763e-01 8.116474e-01 10 101793913 101793998 86 - 1.424 1.382 -0.146
ENSG00000198408 E022 35.3782626 0.0003874096 6.386388e-03 5.911163e-02 10 101793999 101794691 693 - 1.391 1.549 0.543
ENSG00000198408 E023 20.1662272 0.0007058518 8.037087e-01 9.270952e-01 10 101797046 101797979 934 - 1.265 1.282 0.058
ENSG00000198408 E024 44.3389362 0.0034526102 2.035421e-04 4.250035e-03 10 101797980 101798154 175 - 1.739 1.545 -0.658
ENSG00000198408 E025 115.3255964 0.0001417207 6.149799e-07 2.998944e-05 10 101798842 101799451 610 - 2.116 1.971 -0.487
ENSG00000198408 E026 9.5004469 0.0016367979 3.096210e-02 1.657246e-01 10 101799452 101799455 4 - 1.114 0.910 -0.751
ENSG00000198408 E027 29.1297184 0.0004641817 3.968765e-04 7.246153e-03 10 101800242 101800400 159 - 1.568 1.365 -0.700
ENSG00000198408 E028 1.2502498 0.0151005207 5.363797e-01 7.857112e-01 10 101800401 101800533 133 - 0.249 0.350 0.680
ENSG00000198408 E029 9.4200385 0.0016664625 2.975992e-01 5.907297e-01 10 101803735 101803746 12 - 1.044 0.942 -0.377
ENSG00000198408 E030 35.3001286 0.0004258042 4.811224e-02 2.158627e-01 10 101803747 101804019 273 - 1.586 1.479 -0.366
ENSG00000198408 E031 11.4555399 0.0034680012 8.071300e-03 6.951733e-02 10 101806045 101806143 99 - 1.206 0.971 -0.851
ENSG00000198408 E032 22.4145898 0.0007638475 9.555993e-05 2.287915e-03 10 101807730 101807901 172 - 1.488 1.237 -0.873
ENSG00000198408 E033 19.5328616 0.0008286633 1.933011e-02 1.242175e-01 10 101810184 101810314 131 - 1.377 1.213 -0.574
ENSG00000198408 E034 5.1393645 0.0175429425 2.059070e-01 4.894014e-01 10 101812248 101812380 133 - 0.612 0.786 0.724
ENSG00000198408 E035 17.6020860 0.0157343478 3.243630e-01 6.167800e-01 10 101813030 101813127 98 - 1.283 1.196 -0.305
ENSG00000198408 E036 11.0169580 0.0066680778 2.289509e-01 5.177025e-01 10 101813555 101813606 52 - 1.114 0.999 -0.417
ENSG00000198408 E037 22.3558775 0.0006334019 3.899060e-03 4.169976e-02 10 101817824 101818732 909 - 1.448 1.260 -0.655

Help

Please Click HERE to learn more details about the results from DEXseq.