ENSG00000198467

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000329305 ENSG00000198467 No_inf pgKDN_inf TPM2 protein_coding protein_coding 115.3293 112.6382 71.78112 1.096665 1.837809 -0.6499474 3.867384 0.5362595 3.923920 0.3202997 2.266512 2.84830935 0.03544167 0.004675 0.056850 0.052175 0.83269072 0.02063546 FALSE TRUE
ENST00000378292 ENSG00000198467 No_inf pgKDN_inf TPM2 protein_coding protein_coding 115.3293 112.6382 71.78112 1.096665 1.837809 -0.6499474 22.100790 13.4268532 12.330247 1.2549769 1.858946 -0.12282401 0.18061667 0.118975 0.171750 0.052775 0.68005062 0.02063546 FALSE TRUE
ENST00000607559 ENSG00000198467 No_inf pgKDN_inf TPM2 protein_coding protein_coding 115.3293 112.6382 71.78112 1.096665 1.837809 -0.6499474 6.973969 3.6686616 3.482216 1.3435729 1.774195 -0.07503825 0.05512500 0.032725 0.047525 0.014800 1.00000000 0.02063546 FALSE TRUE
MSTRG.28682.4 ENSG00000198467 No_inf pgKDN_inf TPM2 protein_coding   115.3293 112.6382 71.78112 1.096665 1.837809 -0.6499474 21.734278 36.0264861 9.981757 2.8224033 2.184939 -1.85064807 0.19286667 0.320475 0.139325 -0.181150 0.02063546 0.02063546 TRUE TRUE
MSTRG.28682.8 ENSG00000198467 No_inf pgKDN_inf TPM2 protein_coding   115.3293 112.6382 71.78112 1.096665 1.837809 -0.6499474 43.918331 42.5247338 30.792615 2.8354451 1.176366 -0.46558860 0.38913333 0.377050 0.428625 0.051575 0.74205251 0.02063546 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000198467 E001 0.0000000       9 35681992 35681992 1 -      
ENSG00000198467 E002 0.0000000       9 35681993 35682003 11 -      
ENSG00000198467 E003 0.0000000       9 35682004 35682013 10 -      
ENSG00000198467 E004 1.1425607 0.0127347896 1.298920e-02 9.530129e-02 9 35682014 35682016 3 - 0.000 0.418 10.769
ENSG00000198467 E005 1.8943346 0.0072856089 9.811365e-03 7.928771e-02 9 35682017 35682017 1 - 0.125 0.547 2.922
ENSG00000198467 E006 45.3716609 0.0036705991 5.906848e-01 8.188681e-01 9 35682018 35682163 146 - 1.659 1.633 -0.088
ENSG00000198467 E007 0.9903761 0.0647863247 9.052803e-01 9.697005e-01 9 35682164 35682213 50 - 0.301 0.279 -0.149
ENSG00000198467 E008 1.4882208 0.0089380929 9.017495e-01 9.684391e-01 9 35682214 35682268 55 - 0.368 0.387 0.114
ENSG00000198467 E009 10.7220231 0.0120151128 2.646055e-01 5.577315e-01 9 35682269 35682904 636 - 1.113 1.008 -0.383
ENSG00000198467 E010 0.6069161 0.0143733043 2.603250e-01 5.529664e-01 9 35682905 35682931 27 - 0.301 0.134 -1.471
ENSG00000198467 E011 0.4892854 0.0158354112 5.419308e-01   9 35682932 35682936 5 - 0.222 0.134 -0.886
ENSG00000198467 E012 9.9001519 0.0040553118 9.925400e-01 1.000000e+00 9 35682937 35683241 305 - 1.014 1.015 0.007
ENSG00000198467 E013 1.7234816 0.0078004910 5.500529e-01 7.946602e-01 9 35684041 35684245 205 - 0.477 0.387 -0.471
ENSG00000198467 E014 33.9504368 0.0126166969 3.431612e-01 6.344242e-01 9 35684246 35684250 5 - 1.560 1.497 -0.213
ENSG00000198467 E015 62.9356556 0.0079503498 5.651800e-01 8.041158e-01 9 35684251 35684315 65 - 1.799 1.772 -0.090
ENSG00000198467 E016 80.6388105 0.0002618483 6.673771e-01 8.615299e-01 9 35684488 35684550 63 - 1.876 1.892 0.055
ENSG00000198467 E017 4.8534647 0.0050931307 3.721960e-01 6.600642e-01 9 35684551 35684731 181 - 0.668 0.781 0.462
ENSG00000198467 E018 45.9613137 0.0003058103 6.595686e-01 8.579498e-01 9 35684732 35684750 19 - 1.633 1.654 0.074
ENSG00000198467 E019 63.4694982 0.0002364319 3.255734e-01 6.180956e-01 9 35684751 35684807 57 - 1.758 1.798 0.135
ENSG00000198467 E020 12.3542306 0.0020897336 2.244671e-02 1.362186e-01 9 35684808 35685063 256 - 0.954 1.162 0.758
ENSG00000198467 E021 78.8248935 0.0001822096 4.379104e-02 2.044040e-01 9 35685064 35685139 76 - 1.827 1.900 0.246
ENSG00000198467 E022 1.5987655 0.0420922204 4.330244e-01 7.105399e-01 9 35685140 35685144 5 - 0.477 0.354 -0.664
ENSG00000198467 E023 2.3239736 0.0241905045 1.369829e-01 3.939654e-01 9 35685145 35685268 124 - 0.636 0.418 -1.038
ENSG00000198467 E024 86.0758631 0.0025994651 4.853321e-01 7.491887e-01 9 35685269 35685339 71 - 1.932 1.906 -0.086
ENSG00000198467 E025 91.1531893 0.0002382182 8.792195e-01 9.591777e-01 9 35685434 35685505 72 - 1.935 1.942 0.021
ENSG00000198467 E026 77.4208550 0.0007895686 3.375384e-01 6.293412e-01 9 35685506 35685551 46 - 1.891 1.858 -0.112
ENSG00000198467 E027 47.4793108 0.0003613475 1.887022e-02 1.221784e-01 9 35685647 35685666 20 - 1.726 1.624 -0.348
ENSG00000198467 E028 42.3743869 0.0003620982 6.114667e-03 5.727483e-02 9 35685667 35685684 18 - 1.692 1.566 -0.429
ENSG00000198467 E029 79.1645310 0.0002032598 3.393725e-03 3.789589e-02 9 35685685 35685780 96 - 1.942 1.844 -0.331
ENSG00000198467 E030 0.0000000       9 35686351 35686425 75 -      
ENSG00000198467 E031 90.7219593 0.0001879429 2.054276e-02 1.291012e-01 9 35689146 35689271 126 - 1.984 1.912 -0.243
ENSG00000198467 E032 54.7068852 0.0003239532 9.918314e-01 1.000000e+00 9 35689704 35689819 116 - 1.721 1.722 0.003
ENSG00000198467 E033 128.1355663 0.0014609259 2.189567e-07 1.176216e-05 9 35689820 35690432 613 - 1.969 2.135 0.555
ENSG00000198467 E034 30.0169011 0.0028314887 1.120742e-02 8.668595e-02 9 35690433 35690722 290 - 1.355 1.514 0.551

Help

Please Click HERE to learn more details about the results from DEXseq.