ENSG00000198551

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000361113 ENSG00000198551 No_inf pgKDN_inf ZNF627 protein_coding protein_coding 13.84664 11.80778 24.53856 5.288406 18.53211 1.054679 4.0184342 2.8005210 4.392667 1.654302 1.561291 0.6475403 0.5696917 0.264775 0.504900 0.240125 0.84241900 0.04051534 FALSE TRUE
ENST00000588174 ENSG00000198551 No_inf pgKDN_inf ZNF627 protein_coding protein_coding 13.84664 11.80778 24.53856 5.288406 18.53211 1.054679 1.2504644 2.4454032 1.305990 1.415227 1.305990 -0.8998115 0.2071583 0.398550 0.222925 -0.175625 0.85803818 0.04051534 FALSE TRUE
ENST00000593279 ENSG00000198551 No_inf pgKDN_inf ZNF627 protein_coding protein_coding_CDS_not_defined 13.84664 11.80778 24.53856 5.288406 18.53211 1.054679 0.2662416 0.7987247 0.000000 0.150143 0.000000 -6.3375768 0.0371500 0.111450 0.000000 -0.111450 0.04051534 0.04051534   FALSE
MSTRG.14583.7 ENSG00000198551 No_inf pgKDN_inf ZNF627 protein_coding   13.84664 11.80778 24.53856 5.288406 18.53211 1.054679 8.0338454 5.5203446 18.581192 5.520345 18.581192 1.7491780 0.1438750 0.199650 0.231975 0.032325 1.00000000 0.04051534   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000198551 E001 0.0000000       19 11559374 11559447 74 +      
ENSG00000198551 E002 0.0000000       19 11559448 11559460 13 +      
ENSG00000198551 E003 0.7618113 0.014474928 0.01146206 0.08799925 19 11559461 11559616 156 + 0.000 0.392 12.634
ENSG00000198551 E004 0.1186381 0.011796846 0.50356890   19 11562126 11562224 99 + 0.095 0.000 -12.060
ENSG00000198551 E005 0.0000000       19 11564061 11564184 124 +      
ENSG00000198551 E006 0.0000000       19 11564445 11564492 48 +      
ENSG00000198551 E007 0.0000000       19 11575250 11575353 104 +      
ENSG00000198551 E008 0.0000000       19 11575354 11575567 214 +      
ENSG00000198551 E009 0.1272623 0.012620037 0.57579866   19 11597462 11597482 21 + 0.000 0.095 11.869
ENSG00000198551 E010 2.1048905 0.006800564 0.27216559 0.56599108 19 11597483 11597630 148 + 0.393 0.567 0.869
ENSG00000198551 E011 0.6249846 0.027396536 0.19796177 0.47934228 19 11604210 11604364 155 + 0.095 0.296 1.994
ENSG00000198551 E012 0.2454921 0.016254388 0.96495211   19 11611814 11611876 63 + 0.095 0.095 -0.006
ENSG00000198551 E013 3.4213394 0.005079818 0.58971672 0.81834358 19 11614527 11614653 127 + 0.670 0.621 -0.212
ENSG00000198551 E014 0.4814165 0.016927636 0.29243741   19 11614827 11614844 18 + 0.239 0.095 -1.591
ENSG00000198551 E015 1.5712279 0.010861911 0.13523726 0.39090491 19 11614845 11614887 43 + 0.506 0.296 -1.176
ENSG00000198551 E016 1.3355858 0.012720065 0.31978214 0.61257788 19 11616695 11616705 11 + 0.434 0.296 -0.813
ENSG00000198551 E017 74.9000367 0.055389246 0.95001429 0.98707489 19 11616706 11619214 2509 + 1.867 1.892 0.084

Help

Please Click HERE to learn more details about the results from DEXseq.