ENSG00000198598

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000360564 ENSG00000198598 No_inf pgKDN_inf MMP17 protein_coding protein_coding 27.38045 28.82493 25.44969 0.6130791 0.5762083 -0.1796031 9.843372 7.454828 9.599359 0.8390876 1.3336000 0.364331199 0.36163333 0.257225 0.377450 0.120225 0.580246243 0.005635124 FALSE TRUE
ENST00000535004 ENSG00000198598 No_inf pgKDN_inf MMP17 protein_coding nonsense_mediated_decay 27.38045 28.82493 25.44969 0.6130791 0.5762083 -0.1796031 1.754089 0.000000 5.262268 0.0000000 1.8352591 9.042279847 0.06734167 0.000000 0.202025 0.202025 0.009660593 0.005635124 TRUE TRUE
ENST00000535291 ENSG00000198598 No_inf pgKDN_inf MMP17 protein_coding protein_coding 27.38045 28.82493 25.44969 0.6130791 0.5762083 -0.1796031 2.665244 3.625524 1.695372 0.8970857 0.6949104 -1.092076535 0.09721667 0.127050 0.067975 -0.059075 0.754361188 0.005635124 FALSE TRUE
ENST00000537848 ENSG00000198598 No_inf pgKDN_inf MMP17 protein_coding retained_intron 27.38045 28.82493 25.44969 0.6130791 0.5762083 -0.1796031 1.510250 1.299725 1.060497 0.7688821 0.6159606 -0.290982966 0.05365000 0.043925 0.041000 -0.002925 1.000000000 0.005635124 FALSE FALSE
MSTRG.7469.11 ENSG00000198598 No_inf pgKDN_inf MMP17 protein_coding   27.38045 28.82493 25.44969 0.6130791 0.5762083 -0.1796031 1.887191 1.680752 1.679581 0.7773305 0.3047052 -0.001000064 0.06916667 0.059575 0.065775 0.006200 0.864231317 0.005635124 FALSE FALSE
MSTRG.7469.14 ENSG00000198598 No_inf pgKDN_inf MMP17 protein_coding   27.38045 28.82493 25.44969 0.6130791 0.5762083 -0.1796031 4.726832 8.224681 2.397803 0.1273291 0.1944542 -1.773995469 0.16940000 0.285675 0.094025 -0.191650 0.005635124 0.005635124 FALSE TRUE
MSTRG.7469.8 ENSG00000198598 No_inf pgKDN_inf MMP17 protein_coding   27.38045 28.82493 25.44969 0.6130791 0.5762083 -0.1796031 2.566552 3.777896 1.554071 2.3071608 1.5540714 -1.276090454 0.09345833 0.130750 0.065325 -0.065425 0.822155375 0.005635124 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000198598 E001 0.4893478 0.0794252435 7.103633e-01   12 131828393 131828405 13 + 0.201 0.148 -0.534
ENSG00000198598 E002 3.4180721 0.0096600218 1.796036e-01 4.548193e-01 12 131828406 131828494 89 + 0.734 0.562 -0.740
ENSG00000198598 E003 8.5017288 0.0017728621 1.198664e-03 1.718924e-02 12 131828495 131828653 159 + 1.126 0.826 -1.118
ENSG00000198598 E004 1.3414414 0.0097503753 3.596424e-01 6.491183e-01 12 131838056 131838152 97 + 0.442 0.305 -0.797
ENSG00000198598 E005 0.9874780 0.0152994175 8.569432e-01 9.498032e-01 12 131838153 131838194 42 + 0.275 0.305 0.203
ENSG00000198598 E006 12.9721469 0.0014171067 5.138097e-06 1.925769e-04 12 131838195 131838327 133 + 1.317 0.961 -1.278
ENSG00000198598 E007 13.0702761 0.0012209639 8.630670e-03 7.284610e-02 12 131838612 131838741 130 + 1.250 1.048 -0.723
ENSG00000198598 E008 0.1265070 0.0122562755 7.910046e-01   12 131839394 131839455 62 + 0.000 0.080 9.992
ENSG00000198598 E009 0.2541163 0.0159738137 4.014089e-01   12 131840025 131840572 548 + 0.000 0.148 10.931
ENSG00000198598 E010 29.3737521 0.0004669877 4.592657e-07 2.289282e-05 12 131840573 131840856 284 + 1.613 1.350 -0.907
ENSG00000198598 E011 17.4080270 0.0009941011 3.681204e-02 1.847418e-01 12 131841624 131841767 144 + 1.335 1.194 -0.493
ENSG00000198598 E012 9.0327811 0.0016819448 2.089078e-02 1.302871e-01 12 131841768 131841800 33 + 1.106 0.899 -0.768
ENSG00000198598 E013 14.8983244 0.0161787830 2.878536e-02 1.589659e-01 12 131843997 131844081 85 + 1.298 1.107 -0.675
ENSG00000198598 E014 1.8575742 0.0076817793 5.636852e-01 8.029422e-01 12 131844082 131844300 219 + 0.393 0.482 0.466
ENSG00000198598 E015 3.2270579 0.0044239184 3.010605e-01 5.941019e-01 12 131844301 131844535 235 + 0.526 0.669 0.636
ENSG00000198598 E016 1.7038738 0.0100066318 2.219015e-01 5.091424e-01 12 131844536 131844633 98 + 0.526 0.346 -0.948
ENSG00000198598 E017 2.1952402 0.0068232985 2.089026e-01 4.930400e-01 12 131844634 131844760 127 + 0.596 0.420 -0.855
ENSG00000198598 E018 0.4901032 0.0161622764 7.079179e-01   12 131844870 131844960 91 + 0.201 0.148 -0.534
ENSG00000198598 E019 0.4893478 0.0794252435 7.103633e-01   12 131844961 131845117 157 + 0.201 0.148 -0.534
ENSG00000198598 E020 17.0846511 0.0008319470 1.085726e-03 1.595573e-02 12 131845118 131845200 83 + 1.369 1.147 -0.781
ENSG00000198598 E021 24.4251892 0.0014386098 8.409964e-05 2.058933e-03 12 131845297 131845449 153 + 1.520 1.290 -0.794
ENSG00000198598 E022 83.9353399 0.0001941066 1.582478e-33 1.108434e-30 12 131845604 131848751 3148 + 1.619 2.039 1.416
ENSG00000198598 E023 12.6384217 0.0358726484 4.619348e-04 8.217016e-03 12 131848752 131848951 200 + 0.838 1.242 1.485
ENSG00000198598 E024 7.3938299 0.0019175432 3.068438e-04 5.910469e-03 12 131848952 131849033 82 + 0.627 1.032 1.592
ENSG00000198598 E025 4.3761681 0.0033525987 2.729330e-02 1.537054e-01 12 131849034 131849070 37 + 0.526 0.812 1.221
ENSG00000198598 E026 21.9593739 0.0009738023 8.314574e-01 9.391967e-01 12 131849802 131849938 137 + 1.341 1.357 0.058
ENSG00000198598 E027 23.3269970 0.0006023525 6.665726e-01 8.613391e-01 12 131849939 131850059 121 + 1.358 1.387 0.103
ENSG00000198598 E028 0.0000000       12 131850060 131850062 3 +      
ENSG00000198598 E029 116.2537085 0.0001522436 9.076671e-01 9.706955e-01 12 131850925 131851783 859 + 2.058 2.059 0.002

Help

Please Click HERE to learn more details about the results from DEXseq.