ENSG00000198625

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000367179 ENSG00000198625 No_inf pgKDN_inf MDM4 protein_coding protein_coding 18.24443 22.20167 15.26818 2.705165 2.903069 -0.5398451 1.6715342 3.0369102 1.2310894 0.8994966 1.2310894 -1.2957400 0.08764167 0.132700 0.082825 -0.049875 3.742544e-01 9.930644e-10 FALSE TRUE
ENST00000367180 ENSG00000198625 No_inf pgKDN_inf MDM4 protein_coding protein_coding 18.24443 22.20167 15.26818 2.705165 2.903069 -0.5398451 1.0773324 0.8659658 0.4996274 0.8659658 0.4996274 -0.7814318 0.05164167 0.028625 0.021275 -0.007350 9.826355e-01 9.930644e-10 FALSE TRUE
ENST00000367182 ENSG00000198625 No_inf pgKDN_inf MDM4 protein_coding protein_coding 18.24443 22.20167 15.26818 2.705165 2.903069 -0.5398451 4.6731585 4.5353472 6.0077672 1.8732606 1.3794683 0.4048378 0.29498333 0.218475 0.459950 0.241475 6.538618e-01 9.930644e-10 FALSE TRUE
ENST00000391947 ENSG00000198625 No_inf pgKDN_inf MDM4 protein_coding protein_coding 18.24443 22.20167 15.26818 2.705165 2.903069 -0.5398451 0.9872700 1.3674397 0.0000000 1.3674397 0.0000000 -7.1058453 0.05436667 0.070950 0.000000 -0.070950 9.166463e-01 9.930644e-10 TRUE FALSE
ENST00000444261 ENSG00000198625 No_inf pgKDN_inf MDM4 protein_coding protein_coding 18.24443 22.20167 15.26818 2.705165 2.903069 -0.5398451 2.4445959 6.6065737 0.0000000 1.2112323 0.0000000 -9.3699405 0.11041667 0.292375 0.000000 -0.292375 9.930644e-10 9.930644e-10 FALSE FALSE
ENST00000462012 ENSG00000198625 No_inf pgKDN_inf MDM4 protein_coding protein_coding_CDS_not_defined 18.24443 22.20167 15.26818 2.705165 2.903069 -0.5398451 2.9383701 3.6983873 1.7158827 0.6938761 0.6444689 -1.1034575 0.15465000 0.164525 0.106425 -0.058100 7.760545e-01 9.930644e-10 FALSE FALSE
ENST00000470797 ENSG00000198625 No_inf pgKDN_inf MDM4 protein_coding protein_coding_CDS_not_defined 18.24443 22.20167 15.26818 2.705165 2.903069 -0.5398451 1.1965833 1.4401578 0.9391175 0.6862888 0.5607165 -0.6115514 0.06658333 0.058625 0.069825 0.011200 9.545508e-01 9.930644e-10 FALSE TRUE
MSTRG.2563.10 ENSG00000198625 No_inf pgKDN_inf MDM4 protein_coding   18.24443 22.20167 15.26818 2.705165 2.903069 -0.5398451 0.7315762 0.0000000 2.1947285 0.0000000 2.1947285 7.7844572 0.03116667 0.000000 0.093500 0.093500 8.087856e-01 9.930644e-10   FALSE
MSTRG.2563.11 ENSG00000198625 No_inf pgKDN_inf MDM4 protein_coding   18.24443 22.20167 15.26818 2.705165 2.903069 -0.5398451 0.4905686 0.2075470 1.2641589 0.2075470 1.2641589 2.5501462 0.03194167 0.010775 0.085050 0.074275 9.503563e-01 9.930644e-10 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000198625 E001 0.0000000       1 204516379 204516382 4 +      
ENSG00000198625 E002 0.1176306 0.0117617807 3.319588e-01   1 204516383 204516405 23 + 0.114 0.000 -10.317
ENSG00000198625 E003 0.2363338 0.0157273604 1.202997e-01   1 204516406 204516412 7 + 0.204 0.000 -13.107
ENSG00000198625 E004 0.5985480 0.0148982970 6.228282e-02 2.506500e-01 1 204516413 204516419 7 + 0.342 0.079 -2.587
ENSG00000198625 E005 2.4297831 0.0059536679 5.716300e-02 2.389945e-01 1 204516420 204516450 31 + 0.663 0.415 -1.172
ENSG00000198625 E006 2.6654903 0.0058731136 1.970015e-02 1.257262e-01 1 204516451 204516471 21 + 0.716 0.415 -1.395
ENSG00000198625 E007 3.5446202 0.0729472338 2.342122e-01 5.232141e-01 1 204516472 204516509 38 + 0.740 0.579 -0.687
ENSG00000198625 E008 2.3184483 0.0074733223 2.255648e-01 5.133215e-01 1 204525484 204525489 6 + 0.602 0.447 -0.739
ENSG00000198625 E009 2.2010661 0.0073339024 3.374139e-01 6.291907e-01 1 204525490 204525518 29 + 0.568 0.447 -0.587
ENSG00000198625 E010 4.0614730 0.0035388774 6.624793e-01 8.593112e-01 1 204525519 204525596 78 + 0.716 0.681 -0.147
ENSG00000198625 E011 5.0633683 0.0037046120 9.624406e-01 9.918462e-01 1 204526360 204526434 75 + 0.763 0.778 0.057
ENSG00000198625 E012 0.2442663 0.0163277074 7.195697e-01   1 204528095 204528154 60 + 0.114 0.079 -0.587
ENSG00000198625 E013 3.9576263 0.0573041240 9.132215e-01 9.724712e-01 1 204530684 204530734 51 + 0.663 0.698 0.150
ENSG00000198625 E014 5.8681227 0.0024096905 6.201197e-02 2.501349e-01 1 204530735 204530817 83 + 0.929 0.748 -0.707
ENSG00000198625 E015 5.8559105 0.0056040211 3.441193e-02 1.771744e-01 1 204532191 204532246 56 + 0.944 0.732 -0.828
ENSG00000198625 E016 2.7239011 0.1055327175 8.804896e-01 9.597718e-01 1 204532247 204532650 404 + 0.532 0.579 0.219
ENSG00000198625 E017 0.7350260 0.0669117657 5.891288e-01 8.178073e-01 1 204532769 204532819 51 + 0.279 0.204 -0.587
ENSG00000198625 E018 2.4540132 0.0506226825 6.169795e-01 8.341122e-01 1 204536918 204537041 124 + 0.568 0.505 -0.297
ENSG00000198625 E019 3.6679069 0.0587346865 1.553782e-01 4.213026e-01 1 204537430 204537458 29 + 0.764 0.579 -0.780
ENSG00000198625 E020 4.3862602 0.0087609327 4.757644e-02 2.144399e-01 1 204537459 204537497 39 + 0.845 0.623 -0.909
ENSG00000198625 E021 0.7430522 0.1367660134 8.368710e-01 9.415454e-01 1 204537857 204537874 18 + 0.204 0.255 0.412
ENSG00000198625 E022 3.0835207 0.0088653391 8.899672e-01 9.632796e-01 1 204537875 204537991 117 + 0.602 0.602 -0.002
ENSG00000198625 E023 3.4810572 0.0046146216 2.684060e-01 5.618993e-01 1 204537992 204538208 217 + 0.531 0.698 0.735
ENSG00000198625 E024 2.4332475 0.1587497978 4.004631e-01 6.838456e-01 1 204538209 204538220 12 + 0.633 0.447 -0.874
ENSG00000198625 E025 6.0967721 0.0564167454 8.080377e-02 2.921926e-01 1 204538221 204538308 88 + 0.959 0.748 -0.818
ENSG00000198625 E026 2.8346620 0.1013368776 9.104013e-01 9.716396e-01 1 204542784 204542788 5 + 0.568 0.579 0.050
ENSG00000198625 E027 11.9457972 0.0014292775 1.086136e-03 1.595742e-02 1 204542789 204542944 156 + 1.236 0.991 -0.883
ENSG00000198625 E028 12.2992393 0.0011707580 2.775598e-01 5.707699e-01 1 204544535 204544684 150 + 1.152 1.086 -0.239
ENSG00000198625 E029 9.8793660 0.0032310037 9.830462e-01 9.986903e-01 1 204546797 204546877 81 + 1.013 1.033 0.073
ENSG00000198625 E030 15.2580546 0.0009589073 2.659960e-01 5.594579e-01 1 204549113 204549265 153 + 1.236 1.175 -0.213
ENSG00000198625 E031 504.9059964 0.0023838920 3.762579e-07 1.916251e-05 1 204549266 204558120 8855 + 2.652 2.715 0.208

Help

Please Click HERE to learn more details about the results from DEXseq.