ENSG00000198663

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000355190 ENSG00000198663 No_inf pgKDN_inf C6orf89 protein_coding protein_coding 38.7514 26.07826 45.8902 0.8019869 1.887751 0.8151 9.794241 0.7122695 15.20908 0.7122695 1.2886261 4.3972000 0.21880000 0.0253 0.329850 0.304550 1.605978e-03 9.784544e-14 FALSE TRUE
ENST00000480824 ENSG00000198663 No_inf pgKDN_inf C6orf89 protein_coding protein_coding 38.7514 26.07826 45.8902 0.8019869 1.887751 0.8151 12.335769 7.8065888 14.50338 1.1199221 1.5904348 0.8927728 0.31629167 0.3011 0.314700 0.013600 9.723920e-01 9.784544e-14 FALSE TRUE
MSTRG.24620.2 ENSG00000198663 No_inf pgKDN_inf C6orf89 protein_coding   38.7514 26.07826 45.8902 0.8019869 1.887751 0.8151 2.684725 6.9811890 0.00000 0.7513859 0.0000000 -9.4493940 0.09770833 0.2699 0.000000 -0.269900 9.784544e-14 9.784544e-14 TRUE TRUE
MSTRG.24620.7 ENSG00000198663 No_inf pgKDN_inf C6orf89 protein_coding   38.7514 26.07826 45.8902 0.8019869 1.887751 0.8151 11.661646 9.0864948 12.14402 0.1375320 0.2527841 0.4180504 0.30936667 0.3493 0.265575 -0.083725 5.505233e-01 9.784544e-14 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000198663 E001 0.0000000       6 36871870 36871967 98 +      
ENSG00000198663 E002 0.3809703 0.0346197619 7.885180e-02   6 36879008 36879132 125 + 0.000 0.254 10.664
ENSG00000198663 E003 0.2442663 0.0162928779 9.048342e-01   6 36883188 36883352 165 + 0.089 0.102 0.221
ENSG00000198663 E004 0.4901668 0.0833422091 8.873687e-01   6 36885864 36885909 46 + 0.162 0.184 0.221
ENSG00000198663 E005 1.9447381 0.0075984271 4.917507e-01 7.540252e-01 6 36885910 36885951 42 + 0.514 0.413 -0.516
ENSG00000198663 E006 1.7090960 0.0089298685 8.085606e-01 9.293597e-01 6 36885952 36885952 1 + 0.449 0.413 -0.194
ENSG00000198663 E007 11.9703846 0.0511444655 8.893678e-01 9.631574e-01 6 36885953 36886028 76 + 1.122 1.101 -0.075
ENSG00000198663 E008 0.3526461 0.0285938731 1.385065e-01   6 36892766 36892856 91 + 0.225 0.000 -13.534
ENSG00000198663 E009 4.6364716 0.0029068895 8.628621e-01 9.525989e-01 6 36894504 36894603 100 + 0.760 0.740 -0.084
ENSG00000198663 E010 44.2559850 0.0066602084 7.100989e-02 2.699928e-01 6 36899426 36899633 208 + 1.701 1.600 -0.340
ENSG00000198663 E011 22.7125090 0.0037777499 9.061317e-02 3.126659e-01 6 36902221 36902279 59 + 1.425 1.313 -0.389
ENSG00000198663 E012 41.4765675 0.0003493195 3.340582e-02 1.738263e-01 6 36902280 36902434 155 + 1.672 1.574 -0.336
ENSG00000198663 E013 40.3412936 0.0005241465 1.023725e-02 8.156829e-02 6 36914284 36914435 152 + 1.670 1.548 -0.415
ENSG00000198663 E014 40.3275433 0.0013899365 1.293915e-02 9.502453e-02 6 36914554 36914693 140 + 1.670 1.548 -0.415
ENSG00000198663 E015 42.8299351 0.0009679024 5.206419e-02 2.265454e-01 6 36916445 36916574 130 + 1.683 1.592 -0.309
ENSG00000198663 E016 20.2127371 0.0007873053 3.055987e-01 5.989157e-01 6 36919578 36919612 35 + 1.357 1.290 -0.234
ENSG00000198663 E017 26.3246671 0.0005383166 4.379843e-01 7.141808e-01 6 36919613 36919701 89 + 1.457 1.412 -0.155
ENSG00000198663 E018 34.9879847 0.0004275553 2.287044e-05 6.914205e-04 6 36923347 36923486 140 + 1.646 1.430 -0.742
ENSG00000198663 E019 41.2546122 0.0003494415 4.282502e-04 7.727416e-03 6 36923487 36923633 147 + 1.697 1.532 -0.561
ENSG00000198663 E020 156.1533234 0.0001220267 5.119212e-03 5.050640e-02 6 36923634 36924508 875 + 2.226 2.161 -0.214
ENSG00000198663 E021 26.5231828 0.0013451487 1.994657e-01 4.811222e-01 6 36924509 36924693 185 + 1.474 1.399 -0.260
ENSG00000198663 E022 31.8896057 0.0020526133 9.490795e-01 9.867620e-01 6 36924694 36925116 423 + 1.515 1.518 0.011
ENSG00000198663 E023 103.5794649 0.0010104477 4.276843e-03 4.450458e-02 6 36925117 36926653 1537 + 1.975 2.062 0.293
ENSG00000198663 E024 125.6557883 0.0001937428 1.834758e-05 5.733248e-04 6 36926654 36927696 1043 + 2.046 2.156 0.368
ENSG00000198663 E025 190.9830878 0.0001170094 3.346895e-16 6.378495e-14 6 36927697 36928964 1268 + 2.196 2.360 0.548

Help

Please Click HERE to learn more details about the results from DEXseq.