ENSG00000198837

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000477746 ENSG00000198837 No_inf pgKDN_inf DENND4B protein_coding retained_intron 74.49353 90.56913 62.74974 2.855014 3.257881 -0.5293394 4.188224 5.944304 3.321100 1.3111628 1.5898455 -0.8379343 0.05428333 0.065700 0.052075 -0.013625 0.84495250 0.02796743 FALSE TRUE
ENST00000480340 ENSG00000198837 No_inf pgKDN_inf DENND4B protein_coding retained_intron 74.49353 90.56913 62.74974 2.855014 3.257881 -0.5293394 9.630226 15.956419 5.243687 1.6561949 1.4980768 -1.6036386 0.12245833 0.176925 0.081075 -0.095850 0.27342808 0.02796743 TRUE FALSE
ENST00000492898 ENSG00000198837 No_inf pgKDN_inf DENND4B protein_coding retained_intron 74.49353 90.56913 62.74974 2.855014 3.257881 -0.5293394 7.943211 10.630481 8.620751 2.2989022 0.5429630 -0.3020053 0.10567500 0.116050 0.138350 0.022300 0.84312732 0.02796743 TRUE TRUE
MSTRG.1913.1 ENSG00000198837 No_inf pgKDN_inf DENND4B protein_coding   74.49353 90.56913 62.74974 2.855014 3.257881 -0.5293394 9.061016 1.898405 8.995739 1.8984053 3.5069962 2.2384771 0.13691667 0.019300 0.150200 0.130900 0.02796743 0.02796743 FALSE TRUE
MSTRG.1913.3 ENSG00000198837 No_inf pgKDN_inf DENND4B protein_coding   74.49353 90.56913 62.74974 2.855014 3.257881 -0.5293394 11.796101 16.025891 8.372597 0.8772965 0.5527956 -0.9358353 0.15739167 0.177475 0.134525 -0.042950 0.69384263 0.02796743 FALSE TRUE
MSTRG.1913.5 ENSG00000198837 No_inf pgKDN_inf DENND4B protein_coding   74.49353 90.56913 62.74974 2.855014 3.257881 -0.5293394 6.062204 5.690181 7.205447 1.1027254 1.0332204 0.3400811 0.08535833 0.064100 0.114975 0.050875 0.49813056 0.02796743 TRUE TRUE
MSTRG.1913.6 ENSG00000198837 No_inf pgKDN_inf DENND4B protein_coding   74.49353 90.56913 62.74974 2.855014 3.257881 -0.5293394 8.696662 14.406665 8.861852 0.9902114 3.1389272 -0.7004302 0.11242500 0.160325 0.138625 -0.021700 0.85457208 0.02796743 FALSE TRUE
MSTRG.1913.7 ENSG00000198837 No_inf pgKDN_inf DENND4B protein_coding   74.49353 90.56913 62.74974 2.855014 3.257881 -0.5293394 6.128206 7.157706 4.772944 0.6117154 0.5677117 -0.5836126 0.08324167 0.078725 0.077900 -0.000825 1.00000000 0.02796743 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000198837 E001 352.8736412 0.0001816199 1.371703e-01 0.3942626637 1 153929501 153930245 745 - 2.524 2.548 0.079
ENSG00000198837 E002 110.8533352 0.0012129022 4.322806e-01 0.7097080972 1 153930246 153930442 197 - 2.023 2.048 0.084
ENSG00000198837 E003 56.1854687 0.0002957757 3.825991e-01 0.6688414834 1 153930539 153930603 65 - 1.725 1.761 0.122
ENSG00000198837 E004 2.3833351 0.0058526184 1.905148e-02 0.1230418701 1 153930604 153930691 88 - 0.275 0.629 1.886
ENSG00000198837 E005 46.0348477 0.0048862949 8.505760e-02 0.3015709055 1 153930692 153930741 50 - 1.603 1.696 0.316
ENSG00000198837 E006 72.8597356 0.0005555340 9.837842e-01 0.9986902635 1 153930742 153930857 116 - 1.858 1.858 -0.001
ENSG00000198837 E007 12.2268316 0.0011410371 7.178898e-04 0.0115647153 1 153930858 153930946 89 - 0.906 1.206 1.095
ENSG00000198837 E008 53.7947688 0.0057981962 6.932548e-01 0.8746998325 1 153930947 153931022 76 - 1.741 1.721 -0.069
ENSG00000198837 E009 44.1702102 0.0065897901 5.443410e-01 0.7908010701 1 153931023 153931064 42 - 1.665 1.631 -0.116
ENSG00000198837 E010 1.8597116 0.0075456461 5.508115e-01 0.7949074366 1 153932176 153932203 28 - 0.393 0.483 0.471
ENSG00000198837 E011 43.1861076 0.0003181871 3.094307e-01 0.6027860307 1 153932204 153932255 52 - 1.663 1.616 -0.157
ENSG00000198837 E012 94.6039581 0.0001957467 5.642070e-01 0.8034408876 1 153932256 153932440 185 - 1.981 1.963 -0.059
ENSG00000198837 E013 5.6386309 0.1337579413 4.055416e-02 0.1953591528 1 153932441 153932538 98 - 0.525 0.931 1.681
ENSG00000198837 E014 3.8717116 0.0036527356 3.309881e-02 0.1728290639 1 153932539 153932641 103 - 0.485 0.770 1.249
ENSG00000198837 E015 51.5300293 0.0067819619 2.854236e-01 0.5791276190 1 153932642 153932777 136 - 1.743 1.687 -0.190
ENSG00000198837 E016 5.2500072 0.0078190657 9.652869e-03 0.0785482569 1 153932778 153932860 83 - 0.562 0.888 1.345
ENSG00000198837 E017 76.6614139 0.0002038211 7.717972e-01 0.9121857626 1 153932861 153933030 170 - 1.886 1.876 -0.032
ENSG00000198837 E018 2.8652224 0.0058301397 1.431182e-01 0.4029093451 1 153933031 153933196 166 - 0.442 0.650 0.973
ENSG00000198837 E019 55.1958236 0.0054285690 1.387741e-01 0.3961594669 1 153933197 153933319 123 - 1.783 1.709 -0.252
ENSG00000198837 E020 98.2660933 0.0001786642 3.262002e-01 0.6187191644 1 153933483 153933871 389 - 2.004 1.975 -0.099
ENSG00000198837 E021 20.8236193 0.0006238406 2.207343e-05 0.0006699539 1 153933872 153934134 263 - 1.125 1.423 1.044
ENSG00000198837 E022 26.5749733 0.0006331719 3.644040e-01 0.6531442258 1 153934135 153934302 168 - 1.461 1.409 -0.180
ENSG00000198837 E023 0.0000000       1 153934760 153934964 205 -      
ENSG00000198837 E024 6.6808851 0.0255901399 6.081781e-01 0.8293463492 1 153935833 153936059 227 - 0.838 0.899 0.236
ENSG00000198837 E025 29.1399532 0.0032861943 3.247653e-01 0.6171695850 1 153936060 153936188 129 - 1.503 1.446 -0.199
ENSG00000198837 E026 54.0657856 0.0007069537 5.879959e-02 0.2431163944 1 153936542 153936748 207 - 1.777 1.698 -0.266
ENSG00000198837 E027 36.7617573 0.0004094134 2.127647e-01 0.4979713768 1 153937488 153937614 127 - 1.603 1.542 -0.209
ENSG00000198837 E028 41.9092289 0.0054915033 1.800172e-01 0.4553749640 1 153937724 153937863 140 - 1.665 1.592 -0.249
ENSG00000198837 E029 49.5198982 0.0008162265 5.824064e-01 0.8139172059 1 153938900 153939045 146 - 1.707 1.684 -0.080
ENSG00000198837 E030 0.2541163 0.0163439999 3.960830e-01   1 153939588 153939588 1 - 0.000 0.148 9.884
ENSG00000198837 E031 58.3416507 0.0002481714 3.460275e-01 0.6369286744 1 153939589 153939804 216 - 1.785 1.748 -0.125
ENSG00000198837 E032 20.7751897 0.0093944888 3.109162e-03 0.0354373525 1 153939805 153940155 351 - 1.171 1.406 0.824
ENSG00000198837 E033 31.2458180 0.0004741080 3.695550e-01 0.6577427306 1 153940156 153940256 101 - 1.527 1.479 -0.164
ENSG00000198837 E034 43.0164202 0.0006390933 8.951082e-01 0.9652907985 1 153940431 153940606 176 - 1.637 1.631 -0.019
ENSG00000198837 E035 11.3509826 0.0012777602 8.943411e-04 0.0137714968 1 153940607 153940894 288 - 0.873 1.178 1.120
ENSG00000198837 E036 2.3722256 0.0162932865 7.593824e-02 0.2815416016 1 153940895 153940903 9 - 0.338 0.608 1.378
ENSG00000198837 E037 33.1996573 0.0011979803 6.261646e-01 0.8393456763 1 153940904 153941048 145 - 1.507 1.534 0.092
ENSG00000198837 E038 6.9479165 0.0161548406 2.209341e-01 0.5079007857 1 153941049 153941230 182 - 0.799 0.942 0.549
ENSG00000198837 E039 11.5415494 0.0012455617 3.480835e-01 0.6385701125 1 153941231 153941233 3 - 1.135 1.057 -0.283
ENSG00000198837 E040 20.5203925 0.0006709369 2.989184e-01 0.5918387041 1 153941234 153941289 56 - 1.363 1.295 -0.234
ENSG00000198837 E041 16.2643006 0.0128116744 8.847402e-01 0.9611681891 1 153941374 153941394 21 - 1.235 1.222 -0.043
ENSG00000198837 E042 20.8335277 0.0008077210 9.830331e-01 0.9986902635 1 153941395 153941440 46 - 1.328 1.330 0.006
ENSG00000198837 E043 0.8781246 0.0123470124 1.312295e-01 0.3843251558 1 153941441 153941495 55 - 0.112 0.347 2.056
ENSG00000198837 E044 21.8216645 0.0007404412 9.288370e-01 0.9789545544 1 153941869 153941928 60 - 1.351 1.346 -0.018
ENSG00000198837 E045 32.4549574 0.0016081166 1.872205e-01 0.4651963840 1 153941929 153942113 185 - 1.556 1.485 -0.244
ENSG00000198837 E046 1.7480272 0.2654019833 2.288090e-01 0.5175117766 1 153942114 153942186 73 - 0.275 0.511 1.346
ENSG00000198837 E047 17.8723059 0.0007508888 9.093968e-01 0.9712708680 1 153942187 153942278 92 - 1.270 1.263 -0.027
ENSG00000198837 E048 17.6915068 0.0007499212 2.358287e-01 0.5251742832 1 153942279 153942356 78 - 1.310 1.228 -0.288
ENSG00000198837 E049 10.9110587 0.0021853203 1.318439e-01 0.3851832518 1 153942357 153942555 199 - 0.979 1.115 0.496
ENSG00000198837 E050 11.6177016 0.0012125888 3.812280e-02 0.1884442181 1 153942556 153942625 70 - 1.188 1.016 -0.620
ENSG00000198837 E051 2.4688946 0.0062284821 9.341000e-01 0.9810236738 1 153942626 153942802 177 - 0.525 0.537 0.056
ENSG00000198837 E052 31.8108082 0.0029046097 9.464762e-01 0.9856943807 1 153942878 153943130 253 - 1.503 1.508 0.014
ENSG00000198837 E053 39.1200163 0.0003849718 2.622448e-01 0.5550766669 1 153944058 153944397 340 - 1.625 1.571 -0.183
ENSG00000198837 E054 3.9461555 0.0051892046 9.741469e-01 0.9953877330 1 153945135 153945283 149 - 0.683 0.688 0.018
ENSG00000198837 E055 0.3804973 0.0163387722 1.959018e-01   1 153945284 153945349 66 - 0.000 0.207 10.460
ENSG00000198837 E056 0.7273794 0.0140723103 2.081775e-01 0.4918883165 1 153946297 153946300 4 - 0.338 0.148 -1.529
ENSG00000198837 E057 6.6310577 0.0400202375 4.941040e-01 0.7557343870 1 153946301 153946718 418 - 0.922 0.839 -0.315

Help

Please Click HERE to learn more details about the results from DEXseq.