ENSG00000198909

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000361357 ENSG00000198909 No_inf pgKDN_inf MAP3K3 protein_coding protein_coding 14.14862 16.95474 12.5948 0.7766092 0.5034708 -0.4285663 1.468234 0.5323296 1.1142457 0.5323296 1.1142457 1.0517155 0.11310000 0.028800 0.098425 0.069625 0.99557274 0.04650831 FALSE TRUE
ENST00000361733 ENSG00000198909 No_inf pgKDN_inf MAP3K3 protein_coding protein_coding 14.14862 16.95474 12.5948 0.7766092 0.5034708 -0.4285663 1.463729 1.3732998 1.4965069 0.5069710 0.8935002 0.1230934 0.10569167 0.078200 0.118600 0.040400 0.98316705 0.04650831 FALSE TRUE
ENST00000577395 ENSG00000198909 No_inf pgKDN_inf MAP3K3 protein_coding protein_coding 14.14862 16.95474 12.5948 0.7766092 0.5034708 -0.4285663 3.715375 2.4413821 4.9358176 1.4649521 0.9964958 1.0126137 0.27500833 0.142675 0.395825 0.253150 0.41566927 0.04650831 FALSE TRUE
ENST00000577597 ENSG00000198909 No_inf pgKDN_inf MAP3K3 protein_coding nonsense_mediated_decay 14.14862 16.95474 12.5948 0.7766092 0.5034708 -0.4285663 1.161384 2.3184953 0.3106275 2.3184953 0.3106275 -2.8604280 0.07179167 0.125400 0.022575 -0.102825 1.00000000 0.04650831 FALSE TRUE
ENST00000578622 ENSG00000198909 No_inf pgKDN_inf MAP3K3 protein_coding retained_intron 14.14862 16.95474 12.5948 0.7766092 0.5034708 -0.4285663 1.444555 3.2214468 0.5117331 0.7095719 0.3390799 -2.6307962 0.09034167 0.186025 0.038025 -0.148000 0.17149122 0.04650831 FALSE FALSE
ENST00000579585 ENSG00000198909 No_inf pgKDN_inf MAP3K3 protein_coding protein_coding 14.14862 16.95474 12.5948 0.7766092 0.5034708 -0.4285663 2.135198 5.2517841 0.0000000 2.3047755 0.0000000 -9.0394082 0.14003333 0.328500 0.000000 -0.328500 0.04650831 0.04650831 FALSE TRUE
ENST00000584573 ENSG00000198909 No_inf pgKDN_inf MAP3K3 protein_coding protein_coding 14.14862 16.95474 12.5948 0.7766092 0.5034708 -0.4285663 1.579453 0.3039653 3.5291241 0.3039653 1.2212301 3.4947153 0.12077500 0.019200 0.271250 0.252050 0.15910186 0.04650831 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000198909 E001 0.0000000       17 63622415 63622416 2 +      
ENSG00000198909 E002 0.2536433 0.0159698553 3.033785e-01   17 63622417 63622424 8 + 0.000 0.161 10.535
ENSG00000198909 E003 0.3807797 0.0231492720 1.398899e-01   17 63622425 63622437 13 + 0.000 0.224 13.191
ENSG00000198909 E004 0.4984103 0.0226082061 4.063918e-01   17 63622438 63622441 4 + 0.103 0.224 1.336
ENSG00000198909 E005 3.7517429 0.0040992480 3.932468e-02 0.1920617132 17 63622442 63622709 268 + 0.802 0.540 -1.112
ENSG00000198909 E006 1.2986779 0.0393690174 1.488048e-04 0.0032824704 17 63622710 63622716 7 + 0.595 0.000 -15.897
ENSG00000198909 E007 2.4967460 0.0065108784 1.800177e-05 0.0005641532 17 63622717 63622763 47 + 0.783 0.161 -3.497
ENSG00000198909 E008 5.0878281 0.0066205790 8.275237e-03 0.0707316360 17 63632681 63632798 118 + 0.928 0.617 -1.249
ENSG00000198909 E009 2.8053250 0.0081917573 3.166601e-01 0.6095340131 17 63632799 63632802 4 + 0.650 0.511 -0.628
ENSG00000198909 E010 4.2833479 0.0228432561 5.563820e-01 0.7986561750 17 63634709 63634801 93 + 0.764 0.683 -0.331
ENSG00000198909 E011 5.0067064 0.0029355352 3.258891e-01 0.6183682934 17 63646034 63646074 41 + 0.837 0.721 -0.461
ENSG00000198909 E012 9.2811927 0.0016185414 1.622800e-01 0.4306807722 17 63652557 63652656 100 + 1.077 0.947 -0.477
ENSG00000198909 E013 7.5382854 0.0567798263 7.284415e-02 0.2741644513 17 63657794 63657907 114 + 1.047 0.805 -0.913
ENSG00000198909 E014 4.8848581 0.0052483664 2.586458e-01 0.5510489779 17 63666940 63666985 46 + 0.837 0.703 -0.539
ENSG00000198909 E015 8.1013841 0.0019152786 9.367170e-01 0.9819564845 17 63666986 63667060 75 + 0.954 0.958 0.014
ENSG00000198909 E016 0.2541163 0.0161413805 3.029072e-01   17 63668146 63668334 189 + 0.000 0.161 12.675
ENSG00000198909 E017 0.2533610 0.0160709019 3.030741e-01   17 63672845 63672914 70 + 0.000 0.161 12.676
ENSG00000198909 E018 10.7718190 0.0183004192 6.549703e-01 0.8552895180 17 63681766 63681899 134 + 1.096 1.045 -0.183
ENSG00000198909 E019 6.2295441 0.0066693175 3.278600e-01 0.6203839509 17 63685517 63685578 62 + 0.914 0.805 -0.419
ENSG00000198909 E020 1.8521602 0.0086893987 6.495542e-01 0.8523549627 17 63685579 63685590 12 + 0.415 0.480 0.336
ENSG00000198909 E021 3.5256455 0.0240155866 1.502273e-04 0.0033043881 17 63688199 63688526 328 + 0.255 0.820 2.810
ENSG00000198909 E022 4.0251826 0.0043662784 3.270988e-01 0.6195956967 17 63688527 63688528 2 + 0.764 0.640 -0.512
ENSG00000198909 E023 8.4394007 0.0039929508 4.346387e-01 0.7118245086 17 63688529 63688594 66 + 1.014 0.936 -0.291
ENSG00000198909 E024 0.1170040 0.0117018268 4.569804e-01   17 63688742 63688788 47 + 0.103 0.000 -12.959
ENSG00000198909 E025 9.2217619 0.0016111245 7.368913e-01 0.8956859969 17 63688789 63688881 93 + 0.991 1.018 0.099
ENSG00000198909 E026 0.1271363 0.0123395087 6.318199e-01   17 63689287 63689543 257 + 0.000 0.088 11.746
ENSG00000198909 E027 11.4036492 0.0012975046 6.346156e-01 0.8438489006 17 63689544 63689735 192 + 1.114 1.071 -0.156
ENSG00000198909 E028 0.9893022 0.0120266701 6.335076e-01 0.8432696432 17 63689736 63689997 262 + 0.255 0.327 0.488
ENSG00000198909 E029 5.8947561 0.0080697220 9.851286e-01 0.9989950641 17 63690264 63690329 66 + 0.837 0.835 -0.008
ENSG00000198909 E030 7.8457867 0.0017815519 6.885855e-01 0.8717611607 17 63690330 63690412 83 + 0.967 0.925 -0.159
ENSG00000198909 E031 0.6249819 0.0153279630 2.350433e-01 0.5241877012 17 63690993 63691101 109 + 0.103 0.278 1.751
ENSG00000198909 E032 10.2190264 0.0013391621 4.888877e-01 0.7520213853 17 63691102 63691233 132 + 1.014 1.071 0.207
ENSG00000198909 E033 11.7506626 0.0017116784 3.170147e-01 0.6097235712 17 63691733 63691862 130 + 1.148 1.063 -0.309
ENSG00000198909 E034 16.7916713 0.0009221368 4.807714e-01 0.7460464168 17 63692242 63692419 178 + 1.276 1.223 -0.186
ENSG00000198909 E035 166.0867864 0.0001213140 6.097847e-06 0.0002228193 17 63693549 63696305 2757 + 2.177 2.250 0.244

Help

Please Click HERE to learn more details about the results from DEXseq.