ENSG00000198912

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000361605 ENSG00000198912 No_inf pgKDN_inf C1orf174 protein_coding protein_coding 13.89003 13.23891 14.86864 1.153578 0.7948022 0.1673688 9.2461045 5.580979 12.3850927 1.8732649 1.2553762 1.148596 0.65375833 0.412825 0.831775 0.418950 0.231790950 0.005967776 FALSE TRUE
ENST00000474140 ENSG00000198912 No_inf pgKDN_inf C1orf174 protein_coding retained_intron 13.89003 13.23891 14.86864 1.153578 0.7948022 0.1673688 1.0497525 1.462981 0.6415388 0.3487021 0.2288402 -1.176816 0.07800833 0.115350 0.042900 -0.072450 0.538144883 0.005967776 TRUE FALSE
ENST00000680054 ENSG00000198912 No_inf pgKDN_inf C1orf174 protein_coding nonsense_mediated_decay 13.89003 13.23891 14.86864 1.153578 0.7948022 0.1673688 0.5803635 1.067272 0.1259956 1.0672722 0.1259956 -2.985751 0.04750000 0.092075 0.007475 -0.084600 0.998106344 0.005967776 TRUE FALSE
ENST00000681823 ENSG00000198912 No_inf pgKDN_inf C1orf174 protein_coding nonsense_mediated_decay 13.89003 13.23891 14.86864 1.153578 0.7948022 0.1673688 0.6036142 1.810843 0.0000000 1.0859510 0.0000000 -7.508462 0.04317500 0.129525 0.000000 -0.129525 0.467628334 0.005967776 TRUE FALSE
MSTRG.121.1 ENSG00000198912 No_inf pgKDN_inf C1orf174 protein_coding   13.89003 13.23891 14.86864 1.153578 0.7948022 0.1673688 1.3036525 2.921409 0.2344730 0.2690031 0.2344730 -3.583847 0.09720833 0.221375 0.015350 -0.206025 0.005967776 0.005967776 TRUE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000198912 E001 0.3714026 0.0169064173 6.358758e-01   1 3889114 3889124 11 - 0.098 0.168 0.889
ENSG00000198912 E002 0.2442663 0.0163386760 9.478236e-01   1 3889125 3889132 8 - 0.098 0.092 -0.111
ENSG00000198912 E003 0.7244581 0.0141609151 3.575240e-01 6.471408e-01 1 3889133 3889152 20 - 0.305 0.168 -1.111
ENSG00000198912 E004 31.4356431 0.0009370323 5.218295e-01 7.755615e-01 1 3889153 3889746 594 - 1.492 1.525 0.115
ENSG00000198912 E005 35.1089589 0.0004841165 2.070366e-01 4.906759e-01 1 3889747 3890073 327 - 1.584 1.531 -0.181
ENSG00000198912 E006 1.2517907 0.0105111949 6.800707e-02 2.632099e-01 1 3890074 3890568 495 - 0.179 0.460 1.889
ENSG00000198912 E007 25.6194886 0.0007862326 2.161985e-02 1.332318e-01 1 3890569 3890818 250 - 1.484 1.364 -0.414
ENSG00000198912 E008 16.6320597 0.0010212229 3.833690e-01 6.695098e-01 1 3890819 3891057 239 - 1.274 1.219 -0.196
ENSG00000198912 E009 7.6674025 0.0027955768 5.768259e-09 4.273424e-07 1 3891058 3891534 477 - 0.482 1.130 2.617
ENSG00000198912 E010 1.9787928 0.0092695447 4.100327e-01 6.921467e-01 1 3891535 3891625 91 - 0.402 0.526 0.626
ENSG00000198912 E011 2.4690831 0.0805155711 5.602532e-01 8.008878e-01 1 3891626 3891666 41 - 0.482 0.583 0.474
ENSG00000198912 E012 2.7422446 0.0054451933 4.912448e-02 2.185625e-01 1 3891667 3891779 113 - 0.402 0.678 1.304
ENSG00000198912 E013 2.8924200 0.0360581721 1.005369e-03 1.506629e-02 1 3891780 3892740 961 - 0.246 0.757 2.626
ENSG00000198912 E014 3.1283443 0.0051423082 3.924587e-03 4.190629e-02 1 3892741 3892882 142 - 0.356 0.757 1.889
ENSG00000198912 E015 9.4840135 0.0061508041 5.588107e-02 2.355843e-01 1 3892883 3892989 107 - 1.104 0.931 -0.634
ENSG00000198912 E016 3.6217375 0.0756175919 5.674455e-02 2.378165e-01 1 3892990 3892996 7 - 0.802 0.494 -1.334
ENSG00000198912 E017 0.7368846 0.3443052211 9.654889e-01 9.927682e-01 1 3895295 3896183 889 - 0.246 0.232 -0.112
ENSG00000198912 E018 3.8743734 0.0589333397 1.005398e-01 3.311055e-01 1 3900172 3900293 122 - 0.802 0.555 -1.044

Help

Please Click HERE to learn more details about the results from DEXseq.