ENSG00000198961

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000361189 ENSG00000198961 No_inf pgKDN_inf PJA2 protein_coding protein_coding 42.36606 34.68799 50.40966 0.5582062 1.567111 0.5391345 24.75026 11.82560 32.59251 2.297549 2.891979 1.461850 0.5685333 0.341800 0.651300 0.30950 0.04865756 0.04744665 FALSE TRUE
ENST00000361557 ENSG00000198961 No_inf pgKDN_inf PJA2 protein_coding protein_coding 42.36606 34.68799 50.40966 0.5582062 1.567111 0.5391345 16.50630 22.18066 16.55219 2.682289 3.474857 -0.422059 0.4064667 0.638975 0.324925 -0.31405 0.04744665 0.04744665 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000198961 E001 0.3717172 2.075584e-01 4.846195e-01   5 109334713 109334721 9 - 0.084 0.193 1.389
ENSG00000198961 E002 685.5003517 7.069689e-05 2.158485e-11 2.351833e-09 5 109334722 109337356 2635 - 2.812 2.860 0.160
ENSG00000198961 E003 32.0130105 4.303735e-03 8.717432e-02 3.059696e-01 5 109344190 109344311 122 - 1.560 1.458 -0.347
ENSG00000198961 E004 30.6693850 6.656105e-04 6.031792e-01 8.269487e-01 5 109344705 109344819 115 - 1.511 1.483 -0.095
ENSG00000198961 E005 30.7792662 4.735407e-04 4.065421e-01 6.892043e-01 5 109355915 109356026 112 - 1.519 1.475 -0.152
ENSG00000198961 E006 47.9820705 2.870149e-04 8.007569e-02 2.904763e-01 5 109362840 109363022 183 - 1.720 1.645 -0.256
ENSG00000198961 E007 49.6907760 2.250017e-03 1.322937e-01 3.860198e-01 5 109368561 109368746 186 - 1.733 1.664 -0.233
ENSG00000198961 E008 141.2187710 2.718008e-04 4.851947e-04 8.529496e-03 5 109378204 109379166 963 - 2.188 2.101 -0.290
ENSG00000198961 E009 17.9150192 7.653833e-04 2.914175e-02 1.602009e-01 5 109379167 109379254 88 - 1.337 1.184 -0.537
ENSG00000198961 E010 27.4755206 9.339827e-04 3.634431e-01 6.523355e-01 5 109381503 109381703 201 - 1.475 1.423 -0.179
ENSG00000198961 E011 0.0000000       5 109383396 109383402 7 -      
ENSG00000198961 E012 15.4867748 9.777101e-04 2.613050e-02 1.494985e-01 5 109383403 109383520 118 - 1.283 1.116 -0.593
ENSG00000198961 E013 0.6148496 2.073624e-02 4.589027e-01 7.306965e-01 5 109390638 109390758 121 - 0.155 0.265 0.975
ENSG00000198961 E014 0.0000000       5 109409117 109409143 27 -      
ENSG00000198961 E015 0.1265070 1.229270e-02 4.090798e-01   5 109409144 109409316 173 - 0.000 0.107 9.080
ENSG00000198961 E016 7.2432987 3.334035e-03 3.788989e-02 1.878093e-01 5 109409842 109409974 133 - 0.999 0.781 -0.832

Help

Please Click HERE to learn more details about the results from DEXseq.